A5008180015- Food Allergy and Anaphylaxis Research
- Monoclonal and Polyclonal Antibodies Research
- Mast cells and histamine
- Urticaria and Related Conditions
- Glycosylation and Glycoproteins Research
- T-cell and B-cell Immunology
- Asthma and respiratory diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Drug-Induced Adverse Reactions
Sorbonne Université
2016-2018
Institut Pasteur
2016-2018
Inserm
2016-2018
Platelets are key regulators of vascular integrity; however, their role in anaphylaxis, a life-threatening systemic allergic reaction characterized by the loss integrity and leakage, remains unknown. Anaphylaxis is consequence inappropriate cellular responses triggered antibodies to generally harmless antigens, resulting massive mediator release rapidly occurring organ dysfunction. Human platelets express receptors for immunoglobulin G (IgG) can potent mediators, yet contribution anaphylaxis...