Alexandra Martin‐Onraët

ORCID: 0000-0002-8627-404X
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About
Contact & Profiles
Research Areas
  • COVID-19 and healthcare impacts
  • COVID-19 Clinical Research Studies
  • HIV/AIDS Research and Interventions
  • SARS-CoV-2 and COVID-19 Research
  • HIV, Drug Use, Sexual Risk
  • Pneumocystis jirovecii pneumonia detection and treatment
  • HIV/AIDS oral health manifestations
  • Viral-associated cancers and disorders
  • Respiratory viral infections research
  • Tuberculosis Research and Epidemiology
  • Antifungal resistance and susceptibility
  • Cytomegalovirus and herpesvirus research
  • Adolescent Sexual and Reproductive Health
  • Chronic Disease Management Strategies
  • Antibiotic Use and Resistance
  • Infection Control and Ventilation
  • COVID-19 Impact on Reproduction
  • Neutropenia and Cancer Infections
  • Cervical Cancer and HPV Research
  • Vaccine Coverage and Hesitancy
  • Mycobacterium research and diagnosis
  • Infection Control in Healthcare
  • Chemotherapy-related skin toxicity
  • Clostridium difficile and Clostridium perfringens research
  • Immune responses and vaccinations

Instituto Nacional de Cancerología
2015-2025

Instituto Nacional de Cancerología
2023

Universidad Panamericana
2023

Office of Infectious Diseases
2020

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2013

Anal cancer incidence is increased in people with HIV (PWH), up to 60 times higher men who have sex men, and almost 15 among women HIV. Screening treating high-grade lesions (HSIL) proven reduce the of invasive anal cancer. In 2020, we started implementing a high-resolution anoscopy (HRA) clinic at INCan, tertiary care oncologic center, as part screening program for PWH from clinic. We describe barriers difficulties an HRA Clinic January 2020 April 2021, including physician training,...

10.1186/s12981-025-00709-9 article EN cc-by-nc-nd AIDS Research and Therapy 2025-02-11

Antimicrobial resistance is an increasing worldwide concern, which poses unique challenges for the effective prevention and treatment of several infections, especially ones triggered by organisms producing extended-spectrum β-lactamases (ESBL). Here, we present surveillance results Study Monitoring Resistance Trends (SMART) Gram-negative bacilli isolated from intra-abdominal infections (IAI, n = 1,235) urinary-tract (UTI, 2,682), collected in Mexico 2009 to 2015. Susceptibility ESBL status...

10.1371/journal.pone.0198621 article EN cc-by PLoS ONE 2018-06-21

Abstract Background Necrotizing Soft Tissue Infections (NSTI) are severe clinical entities that occur in specific contexts. Although, neutropenia related to hematological malignancies (HM) has been described relation with NSTI, there is a paucity of published data describing its course and outcome this populationTable 1.Population characteristics outcomesAll values represented N(%) unless otherwise noted an asterisk. Variables marked asterisk ( * ), median(interquartile range). LRINEC score:...

10.1093/ofid/ofae631.200 article EN cc-by Open Forum Infectious Diseases 2025-01-29

Abstract Background Respiratory Syncytial Virus (RSV) infection has a high risk of complications in patients with cancer. This study aimed to describe the clinical characteristics and outcomes oncologic infected RSV tertiary care hospital. Methods A retrospective was conducted over ten years at National Cancer Institute Mexico City. Adults confirmed diagnosis cancer by polymerase chain reaction (PCR) were included. Results Fifty-seven cases included, 29 (50.9%) women, median age 48 (IQR...

10.1093/ofid/ofae631.885 article EN cc-by Open Forum Infectious Diseases 2025-01-29

Immunosupressed patients are at high risk of influenza-related complications. Influenza AH1N1 has been hypothesized to induce worse outcomes in with malignancies, but after the A(H1N1)pdm09 few publications have analyzed presentation and complications related influenza afterward.We aimed describe characteristics, factors, an oncologic center 2009 pandemic compare our case distribution National community acquired databases Mexico United States.We reviewed cases confirmed cancer from...

10.1111/irv.12704 article EN cc-by Influenza and Other Respiratory Viruses 2019-11-20

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing disease 2019 (COVID-19) is the most transmissible ß-coronavirus in history, affecting all population groups. Immunocompromised patients, particularly cancer have been highlighted as a reservoir to promote accumulation of viral mutations throughout persistent infection.We aimed describe clinical course and SARS-CoV-2 mutation profile for 102 days an immunocompromised patient with non-Hodgkin's lymphoma COVID-19. We used...

10.3390/v15020377 article EN cc-by Viruses 2023-01-28

Literature on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in cancer patients is scarce Latin America. This population seems to have a higher risk for adverse outcomes. study aims correlate clinical characteristics with outcomes cancer.

10.1002/cam4.4582 article EN cc-by Cancer Medicine 2022-02-14

Tuberculosis (TB) remains a global public health issue, particularly in developing countries. Hematopoietic stem cell transplant (HSCT) recipients are at elevated risk for TB due to immunosuppression. This retrospective study (2005-2022) assessed preemptive latent tuberculosis infection (LTBI) screening and treatment strategy 338 HSCT their donors. Screening included tuberculin skin test (TST) or QuantiFERON-TB Gold (QFT), pulmonary imaging, with positive cases receiving isoniazid (INH)...

10.20944/preprints202406.0458.v1 preprint EN 2024-06-07

Abstract This study aimed to describe the prevalence of high‐risk human papillomavirus (HR‐HPV) types in anal canal a cohort people living with HIV (PLWHIV) history malignancy. Setting Referral tertiary care hospital for adult patients cancer. Methods We reviewed data from AIDS Cancer Clinic on antiretroviral therapy chronic control who were consecutively referred high‐resolution anoscopy (HRA), where they underwent evaluation, collection specimens cytology and (HPV) followed by HRA directed...

10.1111/hiv.13684 article EN HIV Medicine 2024-06-20

We report two cases of adenoviral infection in kidney transplant recipients that presented with different clinical characteristics under similar demographic and posttransplant conditions. The first case fever, gross haematuria, acute graft dysfunction 15 days following renal transplantation. A biopsy, analyzed immunohistochemistry, yielded negative results. However, the diagnosis was confirmed blood urine real-time PCR for adenovirus 3 after initial manifestations. immunosuppression dose...

10.1155/2013/195753 article EN cc-by Case Reports in Nephrology 2013-01-01

Objetivo. Establecer las características y causas de muerte pacientes VIH positivos que fallecen al estar hospitalizados. Material métodos. Se incluyeron fallecieron durante la hospitalización entre 2010 2013. recabaron datos sociodemográficos clínicos, muertes prevenibles. consideraron prevenibles aquellas en con menos seis meses terapia antirretroviral altamente activa (TARAA) o sin tratamiento 350 CD4+ momento del diagnóstico internamiento, enfermedades oportunistas. Resultados....

10.21149/spm.v57s2.7605 article ES cc-by-nc-sa Salud Pública de México 2014-03-05

Invasive fungal infections (IFIs) affect >1.5 million people per year. Nevertheless, IFIs are usually neglected and underdiagnosed. should be considered as a public-health problem major actions taken to tackle them their associated costs. Aim To report the incidence of in four Mexican hospitals, describe economic cost with therapy impact adverse events such acute kidney injury (AKI), liver damage (LD), ICU stay. This was retrospective, transversal study carried-out hospitals. All occurring...

10.1016/j.bjid.2018.10.277 article EN cc-by-nc-nd The Brazilian Journal of Infectious Diseases 2018-09-01

National HIV preventive programs in Mexico focus on high-risk groups that do not consider women, apart from prenatal screening. Nonetheless, the epidemic women is growing, and there a need to better understand sociodemographic factors living with (WLH). We performed case–control study City, including HIV+ HIV− recent pregnancy compare their characteristics describe circumstances of diagnosis as well screening frequency both groups. Fifty cases 102 controls were interviewed. more frequently...

10.1097/md.0000000000007305 article EN cc-by-nc Medicine 2017-07-01

Abstract Objective To determine the prevalence of Latent Tuberculosis in patients with hematological neoplasms at Instituto Nacional de Cancerología Mexico City using Tuberculin skin test (TST). Methods This retrospective study included all a recent diagnosis who were admitted for treatment from 2017 to 2018 and screened latent tuberculosis TST. The this group, tolerance therapeutic adherence treated are described. Results files 446 malignancy had TST reviewed. was 31.2% ( n = 139)....

10.1186/s12879-021-06236-y article EN cc-by BMC Infectious Diseases 2021-05-31

The epidemiology of lymphomas has changed since the use antiretroviral therapy. incidence Non-Hodgkin Lymphomas (NHL) significantly decreased in high income countries but not low and middle-income where AIDS-related events remain high. This observational study describes characteristics, infectious complications main outcomes patients diagnosed with HIV lymphoma at Instituto Nacional de Cancerología.All adults >18 years from January 2010 to December 2017 were included. Information on was...

10.1097/md.0000000000022408 article EN cc-by-nc Medicine 2020-09-30

Vaccination is the best preventive measure for SARS-CoV-2 infection; however, efficacy lower in cancer patients. During pandemic period, Mexico was characterized by use of seven different COVID-19 vaccine platforms, and oncologic patients were not prioritized vaccination. We report outcomes after beginning national campaign Mexico.

10.3390/vaccines12101163 article EN cc-by Vaccines 2024-10-12
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