A5085791022- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Osteoarthritis Treatment and Mechanisms
- Pain Mechanisms and Treatments
- Anesthesia and Pain Management
- Shoulder Injury and Treatment
- Nausea and vomiting management
- Knee injuries and reconstruction techniques
- Musculoskeletal pain and rehabilitation
- Tendon Structure and Treatment
- Lower Extremity Biomechanics and Pathologies
- Bone and Joint Diseases
- Hip disorders and treatments
- Musculoskeletal synovial abnormalities and treatments
- Healthcare and Venom Research
- Sports injuries and prevention
- Foot and Ankle Surgery
- Pain Management and Treatment
- Neuropeptides and Animal Physiology
- Pain Management and Opioid Use
- Venous Thromboembolism Diagnosis and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Veterinary Equine Medical Research
- Sarcoidosis and Beryllium Toxicity Research
Kōchi University
2012-2024
University of Kochi
2012-2013
Abstract Background The subchondral bone of the distal femur is a source pain caused by osteoarthritis ( OA ) or spontaneous osteonecrosis knee. However, nociceptive phenotype dorsal root ganglia DRG neurons innervating in rat knee joints has not been clarified. Methods Retrograde labelling was used to identify afferents and joint rats. markers [calcitonin gene‐related peptide CGRP ), tyrosine receptor kinase A TrkA neurofilament 200 NF 200) isolectin B 4 IB 4)], segmental distribution soma...
Abstract Background Intra‐articular hyaluronic acid ( HA ) injection, known as viscosupplementation, is a widely used therapy for pain relief in knee osteoarthritis OA ). Long‐term clinical efficacy of has been reported spite relatively short residence time. Herein, we evaluated our hypothesis that intra‐articular injection could reduce the ‐associated changes joint afferents. Methods was induced by mono‐iodoacetate rats. Animals + group were given three weekly injections. Pain‐related...
To elucidate the prevalence and risk factors of chronic postsurgical pain (CPSP) after primary total knee arthroplasty (TKA) in Japanese population.Consecutive patients undergoing TKA a tertiary hospital (211 knees) were assessed. CPSP was defined as moderate to severe (VAS >30 mm), either at rest or during walking, one year surgery. Clinical radiographic data compared between non-CPSP groups multivariate logistic regression used identify predictors CPSP.The 8.8%. group showed significantly...
Although disease progression of osteoarthritis has been well documented, pain pathophysiology is largely unknown. This study was designed with two purposes: 1) to characterize patients knee predominantly originating from intra-articular structures and 2) describe the location pattern their pain.103 medial underwent an injection local anesthetics (joint block). At least 70% relief defined as positive for joint block, while less than 50% negative. Pain characteristics in block were evaluated...
Abstract Background Synovial fluid in inflamed joint shows a drop pH , which activates proton‐gated ion channels nociceptors. No studies have ever tried to develop and characterize acid‐induced pain. Methods Rats were injected intra‐articularly with 4.0 acidic saline twice, 5 days apart. Pain‐related behaviour tests including weight‐bearing asymmetry, paw withdrawal threshold knee compression conducted. To clarify the roles of channels, rats selective antagonists for ASIC1a ASIC3 TRPV1 on...
[Purpose] This study aimed to investigate the differential effects of high-intensity and low-intensity transcutaneous electrical nerve stimulation on contralateral side pain threshold in healthy subjects. [Subjects Methods] Twenty-five adults, volunteers received two intensity levels (motor-level, 1.5 times muscle motor threshold; sensory-level, sensory common peroneal nerve), for 30 s separate days. Pressure was recorded tibialis anterior deltoid before, during, after stimulation. [Results]...
Two-stage revision arthroplasty is today considered as the gold standard for control of chronic deep prosthetic infection. Although should only be when infection eliminated, diagnosis residual prior to remains a challenging problem.We evaluated triple-phase bone scintigraphy useful diagnostic test detection around antibiotic-impregnated cement spacer in patients waiting second-stage hip or knee arthroplasty. Increased uptake radioisotope all three phases was positive The final based on...
Some patients experience chronic postsurgical pain (CPSP) after total knee arthroplasty (TKA) despite the absence of clinical or radiographic abnormalities. Postoperative synovitis as a cause CPSP TKA has received limited research attention. This study aimed to investigate relationship between and CPSP.A 111 knees 85 patients, with at least 1-year post-TKA follow-up, were assessed retrospectively cross-sectionally. Power Doppler (PD) ultrasonography was used detect synovial hypervascularity...
<title>Abstract</title> Background Subchondral bone marrow lesions (BMLs) detected on MRI in knee osteoarthritis (OA) are associated with pain. However, the pain mechanisms of BMLs unknown. Increased nerve growth factor (NGF) expression at osteochondral junction and increased osteoclast density subchondral appear to be key features OA. Therefore, this study, we aimed identify association NGF osteoclasts Methods Twenty tibial plateaus were obtained from patients undergoing total arthroplasty...
Generally, painful patella partita is conservatively treated, but the usefulness of a low-intensity pulsed ultrasound (LIPUS) healing apparatus unclear. The objective this study was to investigate LIPUS for conservative treatment partita.The subjects included 17 patients diagnosed with partita. were divided into 2 groups: those without pain at 6 months (responsive group) and that persisted or longer (non-responsive group). reasons different responses between groups investigated. We evaluated...
Abstract Purpose: The cause of residual pain after total knee arthroplasty (TKA) was unknown. Little attention has been given to postoperative synovitis as a unexplained TKA. Here we preliminarily investigated the relationship between TKA and with ultrasonography. Methods: This study conducted using convenient outpatient samples followed for Synovitis accessed We originally made scores, which are summation grade in entire knee. Pain assessments including rest, moving visual analog scale...
Tocilizumab has been used to treat idiopathic multicentric Castleman disease (iMCD). As tocilizumab prevents interleukin-6 from exerting pro-inflammatory effects, there is some concern about a delayed diagnosis of severe infections during treatment. Although serious therapy have previously described in patients with rheumatoid arthritis, they not reported iMCD. We herein report case disseminated Staphylococcus aureus infection after superficial skin wound followed by psoas and mediastinal...