A5075485466- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Neuroscience and Music Perception
- Neural and Behavioral Psychology Studies
- Advanced MRI Techniques and Applications
- Neural Networks and Applications
- Epilepsy research and treatment
- Advanced Neuroimaging Techniques and Applications
- Hearing Loss and Rehabilitation
- Blind Source Separation Techniques
- Electrical and Bioimpedance Tomography
- Multisensory perception and integration
- Face Recognition and Perception
- Memory and Neural Mechanisms
- Fractal and DNA sequence analysis
- Healthcare Technology and Patient Monitoring
- Fetal and Pediatric Neurological Disorders
- Music and Audio Processing
- Electrochemical Analysis and Applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Hearing Impairment and Communication
- Psychology of Moral and Emotional Judgment
- Motor Control and Adaptation
- Bipolar Disorder and Treatment
University of Oslo
2017-2025
Center for Interdisciplinary Studies
2020-2024
Consejo Nacional de Investigaciones Científicas y Técnicas
2011-2020
Hospital El Cruce
2016-2020
University of Buenos Aires
2011-2017
Hospital Ramos Mejía
2011-2017
Universidad Nacional Arturo Jauretche
2017
Favaloro University
2012-2013
Centro Científico Tecnológico - San Juan
2011-2012
Universidad Nacional de La Plata
2011-2012
Hierarchical predictive coding suggests that attention in humans emerges from increased precision probabilistic inference, whereas expectation biases favor of contextually anticipated stimuli. We test these notions within auditory perception by independently manipulating top-down and attentional alongside bottom-up stimulus predictability. Our findings support an integrative interpretation commonly observed electrophysiological signatures neurodynamics, namely mismatch negativity (MMN),...
Although it has been shown that adults with attention-deficit hyperactivity disorder (ADHD) have impaired social cognition, no previous study reported the brain correlates of face valence processing. This looked for behavioral, neuropsychological, and electrophysiological markers emotion processing faces (N170) in adult ADHD compared to controls matched by age, gender, educational level, handedness. We designed an event-related potential (ERP) based on a dual task (DVT), which words were...
Brain function can be conceived as a hierarchy of generative models that optimizes predictions sensory inputs and minimizes "surprise." Each level the makes neural events at lower in hierarchy, which returns prediction error when these expectations are violated. We tested generalization this hypothesis to multiple sequential deviations, we identified most likely organization network accommodates deviations temporal structure stimuli. Magnetoencephalography healthy human participants during...
Abstract Contextual cues and prior evidence guide human goal-directed behavior. The neurophysiological mechanisms that implement contextual priors to subsequent actions in the brain remain unclear. Using intracranial electroencephalography (iEEG), we demonstrate increasing uncertainty introduces a shift from purely oscillatory mixed processing regime with an additional ramping component. Oscillatory dynamics reflect dissociable signatures, which likely differentially contribute encoding...
We propose that sensory inputs are processed in terms of optimised predictions and prediction error signals within hierarchical neurocognitive models. The combination non-invasive brain imaging generative network models has provided support for frontotemporal interactions oddball tasks, including recent identification a temporal expectancy signal acting on prefrontal cortex. However, these studies limited by the need to invert magnetoencephalographic or electroencephalographic sensor...
Background Adults with bipolar disorder (BD) have cognitive impairments that affect face processing and social cognition. However, it remains unknown whether these deficits in euthymic BD impaired brain markers of emotional processing. Methodology/Principal Findings We recruited twenty six participants, 13 controls subjects an equal number participants. used event-related potential (ERP) assessment a dual valence task (DVT), which faces (angry happy), words (pleasant unpleasant), face-word...
The localization of intracranial electrodes is a fundamental step in the analysis invasive electroencephalography (EEG) recordings research and clinical practice. conclusions reached from these rely on accuracy electrode relationship to brain anatomy. However, currently available techniques for localizing magnetic resonance (MR) and/or computerized tomography (CT) images are time consuming limited particular types or shapes. Here we present iElectrodes, an open-source toolbox that provides...
Experimental findings show the ubiquitous presence of graded responses and tuning curves in neocortex, particularly visual areas [1Tanaka K. Inferotemporal cortex object vision.Annu. Rev. Neurosci. 1996; 19: 109-139Crossref PubMed Scopus (1019) Google Scholar, 2Logothetis N.K. Sheinberg D.L. Visual recognition.Annu. 577-621Crossref (820) 3Hubel D.H. Wiesel T.N. Receptive fields single neurones cat's striate cortex.J. Physiol. 1959; 148: 574-591Crossref (2519) 4Ito M. Tamura H. Fujita I....
The human prefrontal cortex (PFC) constitutes the structural basis underlying flexible cognitive control, where mixed-selective neural populations encode multiple task features to guide subsequent behavior. mechanisms by which brain simultaneously encodes task–relevant variables while minimizing interference from task-irrelevant remain unknown. Leveraging intracranial recordings PFC, we first demonstrate that competition between coexisting representations of past and present incurs a...
Emerging research supports a role of the insula in human cognition. Here, we used intracranial EEG to investigate spatiotemporal dynamics during verbal working memory (vWM) task. We found robust effects for theta, beta, and high frequency activity (HFA) probe presentation requiring decision. Theta band showed differential involvement across left right insulae while sequential HFA modulations were observed along anteroposterior axis. anterior tracked decision making subsequent was posterior...
Depth intracranial electrodes (IEs) placement is one of the most used procedures to identify epileptogenic zone (EZ) in surgical treatment drug resistant epilepsy patients, about 20-30% this population. IEs localization therefore a critical issue defining EZ and its relation with eloquent functional areas. That information then target resective surgery has great potential affect outcome. We designed methodological procedure intended avoid need for highly specialized medical resources reduce...
Orbitofrontal cortex (OFC) is classically linked to inhibitory control, emotion regulation, and reward processing. Recent perspectives propose that the OFC also generates predictions about perceptual events, actions, their outcomes. We tested role of in detecting violations prediction at two levels abstraction (i.e., hierarchical predictive processing) by studying event-related potentials (ERPs) patients with focal lesions (n = 12) healthy controls 14) while they detected deviant sequences...
Purpose . The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates surgery. Methods Twenty were evaluated prospectively between 2007 2010 comprehensive clinical evaluation, video-electroencephalography, diffusion tensor imaging (DTI), high-resolution EEG localize equivalent current dipole (ECD). Key Findings In 11 cases white matter asymmetries DTI ECDs...
Abstract The brain responds to violations of expected rhythms, due extraction- and prediction the temporal structure in auditory input. Yet, it is unknown how probability rhythm affects overall predictability. Another unresolved question whether predictive processes are independent attention processes. In this study, EEG was recorded while subjects listened rhythmic sequences. Predictability manipulated by changing stimulus-onset-asynchrony (SOA deviants) for given tones rhythm. When SOA...
Orbitofrontal cortex (OFC) is implicated in multiple cognitive processes, including inhibitory control, context memory, recency judgment, and choice behavior. Despite an emerging understanding of the role OFC memory executive its necessity for core working (WM) operations remains undefined. Here, we assessed impact damage on interference effects WM using a Recent Probes task based Sternberg item-recognition (1966). Subjects were asked to memorize set letters then indicate whether probe...
The major goal of evoked related potential studies arise in source localization techniques to identify the loci neural activity that give rise a particular voltage distribution measured on surface scalp.In this paper we evaluate effect head model adopted order estimate N170 component attention deficit hyperactivity disorder (ADHD) patients and control subjects, considering faces words stimuli.The standardized low resolution brain electromagnetic tomography algorithm (sLORETA) is used compare...
Abstract The brain excels at processing sensory input, even in rich or chaotic environments. Mounting evidence attributes this to the creation of sophisticated internal models environment that draw on statistical structures unfolding input. Understanding how and where modeling takes place is a core question learning predictive processing. In context, we address role transitional probabilities as an implicit structure supporting encoding random auditory stream. Leveraging...
Information theory is a viable candidate to advance our understanding of how the brain processes information generated in internal or external environment. With its universal applicability, enables analysis complex data sets, free requirements about structure, and can help infer underlying mechanisms. Information-theoretical metrics such as Entropy Mutual have been highly beneficial for analyzing neurophysiological recordings. However, direct comparison performance these methods with...