Leonardo Simões

ORCID: 0000-0002-8676-4479
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About
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Research Areas
  • Spine and Intervertebral Disc Pathology
  • Scoliosis diagnosis and treatment
  • Spinal Fractures and Fixation Techniques
  • Advanced machining processes and optimization
  • Musculoskeletal pain and rehabilitation
  • Medical Imaging and Analysis
  • Advanced Machining and Optimization Techniques
  • Mineral Processing and Grinding
  • Research on Leishmaniasis Studies
  • Case Reports on Hematomas
  • Microwave Dielectric Ceramics Synthesis
  • Advanced Surface Polishing Techniques
  • Reproductive System and Pregnancy
  • Computational Drug Discovery Methods
  • Biotechnology and Related Fields
  • Advanced ceramic materials synthesis
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Ferroelectric and Piezoelectric Materials
  • Pelvic and Acetabular Injuries
  • Reproductive tract infections research
  • Spinal Hematomas and Complications
  • Cholinesterase and Neurodegenerative Diseases

Universidade Estadual Paulista (Unesp)
2017-2023

McGill University
2016-2020

McGill University Health Centre
2020

Montreal General Hospital
2015

Spontaneous spinal epidural hematoma (SSEH) manifests from blood accumulating in the space, compressing cord and leading to acute neurological deficits. Standard therapy is decompressive laminectomy, although spontaneous recoveries have been reported. Sub-optimal therapeutic principles contribute SSEH's 5.7% mortality-which patient will benefit surgery remains unclear. This study aims investigate parameters that affect progression, outlining a best-practice approach.Literature review yielded...

10.1038/scsandc.2016.43 article EN cc-by Spinal Cord Series and Cases 2017-02-02

Grinding is a finish process of parts that require high precision and tight dimensional tolerance, which owe value-added. As the grinding takes place, cutting surface wheel undergoes wear then its capacity reduced. On other hand, dressing operation responsible for restoring and, therefore, plays key role in process. This work aims at obtaining acoustic images to identify conditions during operation. Experimental tests were conducted with single-point diamond dresser machine, was equipped an...

10.1016/j.procir.2019.02.070 article EN Procedia CIRP 2019-01-01

Study Design. Retrospective radiographic reliability study. Objective. The aim of this study was to assess the validity EOS 3D imaging technology in determination vertebral rotations spine patients with previous instrumentation. Summary Background Data. There is a lack evidence on accuracy rotational measurement using morphological analysis instrumented spine. Methods. A retrospective review 31 adolescent idiopathic scoliosis (AIS) who underwent fusion and postoperative computed tomography...

10.1097/brs.0000000000003739 article EN Spine 2020-10-08

CONSTRUCTION, OPTIMIZATION AND MOLECULAR DOCKING OF BIOACTIVE SUBSTANCES IN BIOMACROMOLECULES: A PRACTICAL TUTORIAL. In the last two decades, increasing advances in molecular biology and instrumental analysis for solving macromolecular structures have amplified applicability of cheminformatics drug discovery. particular, docking, an silico structural-based method, has prospered as efficient tool understanding interactions that drives formation stable receptor-ligand systems. Brazil affords...

10.21577/0100-4042.20170821 article EN cc-by-nc Química Nova 2021-01-01

Introduction Adolescent Idiopathic Scoliosis (AIS) has been thought to be a relatively painless three dimensional (3D) deformity of the spine, but some studies shown that incidence mild moderate pain in AIS ranges from 25 50%. With arrival new low dose radiation EOS technology, it is now possible quantify intersegmental changes scoliotic spine an upright position could related pain. Hypothesis 3D morphological analysis patients will better correlate with presence than Lenke classification....

10.1055/s-0036-1582667 article EN cc-by-nc-nd Global Spine Journal 2016-04-01

Introduction Current surgical treatment modalities available for the of early onset scoliosis, either spine based Duel Growing Rods, or rib VEPTR construct, require repetitive lengthening surgeries with no apical control deformity. The overall results these techniques have shown to provide some benefits. However they remain a high rate complications, in part related frequent surgeries. A new gliding spinal anchor know as Trolley Gliding Vehicle (TGV) and technique has been developed hope...

10.1055/s-0036-1582743 article EN cc-by-nc-nd Global Spine Journal 2016-04-01

Grinding is a high-precision, high-value-added finishing process as it usually the last stage of manufacturing chain. However, unsatisfactory results may occur, mainly due to changes in microstructure ground workpiece. Such are caused by high temperatures involved grinding conditions which part was subjected. In this way, main objective work monitoring order detect signal and relate them with damage occurred The tests were carried out on surface machine, aluminum oxide wheel ABNT 1045 steel...

10.18502/keg.v3i1.1446 article EN KnE Engineering 2018-02-11
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