- Oral and Maxillofacial Pathology
- Bone Tumor Diagnosis and Treatments
- dental development and anomalies
- Salivary Gland Tumors Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Rheumatoid Arthritis Research and Therapies
- Sarcoma Diagnosis and Treatment
- Cancer and Skin Lesions
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory Myopathies and Dermatomyositis
- Tumors and Oncological Cases
- Drug-Induced Adverse Reactions
- Clinical practice guidelines implementation
- Immunodeficiency and Autoimmune Disorders
- Biosimilars and Bioanalytical Methods
- Cardiac, Anesthesia and Surgical Outcomes
- Breast Lesions and Carcinomas
- Cancer Diagnosis and Treatment
- Asthma and respiratory diseases
- Urologic and reproductive health conditions
- Pancreatic and Hepatic Oncology Research
- Testicular diseases and treatments
- Electronic Health Records Systems
- Oral and gingival health research
- Chronic Lymphocytic Leukemia Research
The University of Texas Southwestern Medical Center
2016-2025
Southwestern Medical Center
2024
Donaldson (United States)
2023
Dartmouth Institute for Health Policy and Clinical Practice
2023
Nationwide Children's Hospital
2023
Geisinger Health System
2019
Northwell Health
2016
Stony Brook University Hospital
2016
Lady Hardinge Medical College
1991-2015
Penn State Milton S. Hershey Medical Center
2011-2014
Objective Biological drugs have revolutionized the treatment of rheumatic diseases, but their high cost has contributed to increased prescription drug spending in United States. The US Food and Drug Administration approved use several biosimilars, medications that are like reference biologics with comparable safety effectiveness, for diseases. We describe a reduction project at large academic medical center aimed increasing biosimilars rituximab infliximab within rheumatology clinics....
We sought to demonstrate applicability of user stories, progressively elaborated by testable acceptance criteria, as lightweight requirements for agile development clinical decision support (CDS).User stories employed the template: As a [type user], I want [some goal] so that reason]. From "so that" section, CDS benefit measures were derived. Detailed criteria through ensuing conversations. estimated story size with "story points," and depicted multiple use case diagram or feature breakdown...
Dashboards can support person-centered care by helping people partner with their clinicians to coproduce based on preferences, shared decision-making, and evidence-based treatments. We engaged caregivers of children juvenile idiopathic arthritis (JIA), adults rheumatoid (RA), in a pilot study assess experiences the utility impact an electronic previsit questionnaire point-of-care dashboard coproduction rheumatology care.We employed mixed-methods design users' perceptions customized health...
Inflammatory lung diseases such as asthma and chronic obstructive pulmonary disease are common difficult to diagnose characterize. This is due in large part difficulty obtaining samples directly from the inflamed lung. The collection of secretions by traditional methods including bronchoalveolar lavage induced sputum limited their invasive nature. Exhaled breath condensate (EBC) a simple non-invasive technique collecting fluid samples, which representative airway lining fluid. Advances...
Abstract We report on the cytopathologic findings of a Leydig‐cell tumor testis in young adult male with no evidence endocrine dysfunction. The preoperative diagnosis was based fine‐needle aspiration cytology (FNAC) alone, which subsequently confirmed histopathology. present case interest account paucity literature regarding cytodiagnosis this lesion. In addition, finding intracytoplasmic lipofuscin pigment and several as well intranuclear Reinke's crystals served to clinch FNA. Therefore,...
Patient-reported outcomes (PROs) are an integral part of treat-to-target approaches in managing rheumatoid arthritis (RA). In clinical practice, however, routine collection, documentation, and discussion PROs with patients highly variable. The RISE LC (Rheumatology Informatics System for Effectiveness Learning Collaborative) was established to develop share best practices PRO collection use across adult rheumatology the United States METHODS: goals were developed through site surveys...
Fingerprint (dermatoglyphic) evidence is undoubtedly the most reliable and acceptable till date in court of law. Due to immense potential fingerprint as an effective method identification.
Diffuse erythematous rash accompanied by high-grade fever, eosinophilia, and facial edema can be caused a variety of infective, allergic, or systemic etiologies. We present case 65-year-old man with septic arthritis, who had vancomycin antibiotic spacer placed in his infected knee was also started on intravenous (i.v.) vancomycin. After 2 weeks he presented sudden onset fever generalized weakness. Physical examination significant for tachycardia hypotension, edema, diffuse rash, bilateral...
Background: Aspirin (ASA) desensitization and continuous daily ASA therapy is the criterion standard treatment for ASA-exacerbated respiratory disease (AERD). However, optimal maintenance dosage of safety "bridging" patients with AERD alternative cyclooxygenase-1 inhibitors surgery have not been determined require further investigation. Objective: This study was designed to compare long-term effects different doses assess success bridging subjects without losing desensitization. Methods: We...
Fever of unknown origin in patients with common variable immune deficiency (CVID) can be caused by variety infectious, autoimmune, or malignancy-related etiologies. We present a 52-year-old man history CVID, who presented 3 weeks persistent high-grade fevers. During admission, he developed severe pancytopenia shock and multiorgan failure. An extensive workup was performed for typical atypical infections, autoimmune pathologies, malignancy. His peripheral blood smear showed marked...
Age estimation is an important subspecialty of forensic medicine. Dental hard tissues are highly resistant to degradation and putrefaction. Enamel translucent varies in color from light yellow grey white. The the teeth has been reported be affected by chronological age. may also depend on environmental factors viz. diet, occupational habits, vitamin deficiencies, fluoride level drinking water etc., It found that changes dentin vary white yellow. Studies have done measure for age...
Objective Rheumatoid arthritis (RA) disease activity assessment is critical for treatment decisions and treat to target (T2T) outcomes. Utilization of the electronic medical record (EMR) techniques improve routine capture measures in clinical practice are not well described. We leveraged a Lean Six Sigma (LSS) approach, data‐driven five‐step process improvement problem‐solving methodology, coupled with EMR modifications evaluate documentation patient Methods A RA registry was established,...
The cytologic appearance of epithelioid sarcoma in fine-needle aspiration biopsy cytology (FNABC) smears has not been extensively described. We report a case 55-year-old male who presented with nodular swellings the abdominal wall and scrotum. scrotal swelling was subsequently demonstrated to arise from vas deferens. highlight cytomorphologic, immunocytochemical, histopathologic features this rare lesion an unusual site, particular emphasis on dilemma encountered cytodiagnosis lesion. Diagn....
Patients with rheumatic disease are at increased risk for herpes zoster infection. Because of limited safety data in this population and concerns over vaccine-precipitated flares, there no guidelines vaccination the vaccine recombinant, adjuvanted (ZRA). We evaluated self-reported adverse events (AEs) activity after ZRA administration adults disease.In medical records review study our large academic center, patients who had received least 1 dose from January 1, 2018 to March 11, 2020 were...
A woman in her late 30s recently diagnosed with viral myopericarditis presented 1 month of worsening fatigue, diffuse myalgias and chest pain radiating to back. While undergoing work-up for wall myositis, she rapidly decompensated, developing heart failure acute hypoxaemic respiratory failure. Her clinical course was complicated by cardiac arrest severe cardiogenic shock requiring intra-aortic balloon pump support.
The American College of Rheumatology endorses 7 rheumatoid arthritis (RA) quality indicators (QIs), which we used to access care at our institution.The aim this study was assess the provided RA patients outpatient rheumatology practice based on adherence QIs.We performed a retrospective paper chart review and included 356 determine each QI. A χ test analyzed trends in assessment disease activity functional status.There excellent disease-modifying antirheumatic drug therapy (99.4%) managing...
Objective Rheumatology patients are at high risk for complications from pneumococcal infections. The goal of this study was to assess the feasibility implementing a nurse-driven vaccination protocol based on 2012 Advisory Committee Immunization Practices (ACIP) guidelines within an academic rheumatology clinic. Our aims were increase (1) conjugate vaccine (PCV13) and polysaccharide (PPSV23) monthly rates in immunosuppressed aged 19 64 years, (2) overall proportion years who have received...
Abstract Purpose To assess the impact of a clinical pharmacy specialist (CPS) embedded within rheumatology clinic at large academic medical center on prescription capture rate health-system specialty pharmacy. Methods Initially low rates for led to integration CPS in main campus clinic. Benchmarking was completed by assessing prior using electronic record analytics and Loopback Analytics (a database pharmacy). The existing workflows both were observed with regard biologic medication ordering...