A5035360902- Pharmaceutical Practices and Patient Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Failure Treatment and Management
- Obesity, Physical Activity, Diet
- Medication Adherence and Compliance
- Health Systems, Economic Evaluations, Quality of Life
- Global Health Care Issues
- Nutritional Studies and Diet
- Microbial Metabolism and Applications
- Blood Pressure and Hypertension Studies
- Patient Safety and Medication Errors
- Health disparities and outcomes
- Diabetes Management and Education
- Chronic Disease Management Strategies
- Pharmacy and Medical Practices
- Body Composition Measurement Techniques
- Healthcare Systems and Practices
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular and exercise physiology
- Cardiovascular Disease and Adiposity
- Pharmacovigilance and Adverse Drug Reactions
- Biosimilars and Bioanalytical Methods
- Antibiotic Use and Resistance
- Chemical Synthesis and Analysis
- Cardiovascular Health and Risk Factors
University College Cork
2015-2025
University College Dublin
2011-2017
St. Vincent's University Hospital
2011-2014
Trinity College Dublin
2014
St Michael’s Hospital
2013
The University of Sydney
1973-2007
Saint Luke's Hospital
1968
Angal Hospital
1968
Queen Mary University of London
1963
IMPORTANCEPrevention strategies for heart failure are needed.OBJECTIVE To determine the efficacy of a screening program using brain-type natriuretic peptide (BNP) and collaborative care in an at-risk population reducing newly diagnosed prevalence significant left ventricular (LV) systolic and/or diastolic dysfunction. DESIGN, SETTING, AND PARTICIPANTSThe St Vincent's Screening to Prevent Heart Failure Study, parallel-group randomized trial involving 1374 participants with cardiovascular risk...
Increasing numbers of biosimilar medicines are becoming available. The objective this survey was to assess awareness and attitudes biosimilars amongst physicians (medical specialists General Practitioners (GPs)) community pharmacists in Ireland. Physicians were invited complete an online questionnaire during April May 2016. Community received a postal August 2015. Responses from 102 medical specialists, 253 GPs 125 analysed. majority (85%) (77%) claimed be either very familiar or with the...
In Europe, changes to pharmacovigilance legislation, which include additional monitoring of medicines, aim optimise adverse drug reaction (ADR) reporting systems. The legislation also makes provisions related the traceability biological medicines.The objective this study was assess (i) knowledge and general experience ADR reporting, (ii) knowledge, behaviours, attitudes biologicals, (iii) awareness among healthcare professionals (HCPs) in Ireland.Hospital doctors (n = 88), practitioners...
Palatability is a key element influencing medicine's acceptability for patients. While the relationship between and taste has been widely explored, odour its received less investigation. In this study of range oral flucloxacillin formulations was assessed by human volunteers. The malodour flucloxacillin, prescribed antibiotic, related to poor palatability amongst children. parallel assessing formulations' acceptability, smell acuity volunteers also determined. commercial solution capsule...
Abstract Background Cardiovascular disease (CVD) is the leading cause of mortality and disability globally. We examined healthcare service utilization costs attributable to CVD in Ireland period before introduction a major reform 2016. Methods Secondary analysis data from 8113 participants first wave The Irish Longitudinal Study on Ageing. was defined as having self-reported doctor's diagnosis myocardial infarction, angina, heart failure, stroke, atrial fibrillation, or transient ischaemic...
Abstract Background Palatability is a key element of paediatric acceptability for medicines. Many patient and drug factors are considered when choosing an antibiotic child. Pharmacists report that they receive questions about the palatability oral liquid antibiotics children. This study aimed to explore experiences GPs pharmacists concerning Methods A questionnaire impact on choice formulation children was emailed all community in Ireland trainee Cork region posted social media. Survey items...
<i>Background/Aim:</i> Despite evidence linking type of obesity with subsequent organ malfunction, such a link renal malfunction has not been widely researched. The aim this study was to investigate percentage total body fat (%TBF), and distribution in relation the function overweight/obese subjects. <i>Methods:</i> Body mass index (BMI), waist-to-hip ratio (WHR), TBF (by bioelectric impedance), albumin excretion rate (AER) were determined 77 subjects: 48 (BMI ≧27.8...
Background- Aspirin use in heart failure (HF) is controversial. The drug has proven benefit comorbidities associated with HF; however, retrospective analysis of angiotensin-converting enzyme inhibitor trials and prospective comparisons warfarin have shown increased risk morbidity aspirin use. This study aims to evaluate the association low-dose mortality a large community-based cohort. Methods Results- was cohort patients attending an HF disease management program. at baseline its...
The investigators were invited into a boys' high school to assess the lipid risk profile of single year cohort and advise on how findings could be incorporated healthy lifestyle program. aim study was investigate relationship between measures fatness, ethnicity cardiac factors in adolescent boys.Anthropometric measurements weight, height, waist hips used calculate body mass index (BMI) hip ratio (WHR); percent total fat (%TBF) estimated by bioelectric impedance analysis. Demographic...
Uniformly labelled radioactive glucose was fed to Chlorella cells in the presence of non-radioactive carbon dioxide. The concentration dioxide varied and distribution radioactivity determined light. At low concentrations much appeared glycollate or derivatives thereform. By contrast, at higher dioxide, most sucrose. If oxygen increased above that normally present air, there relatively more activity glycollate. effect addition isoniazid these conditions also investigated. It concluded...
The addition of low concentrations streptomycin (5–10μg/ml medium) to Serratia marcescens caused significant alterations in the lipid composition this organism, but neither growth nor pigmentation was affected. acetone-soluble cyclic depsipeptides, which comprise on average 15% total lipid, were decreased almost zero and phosphorus more than doubled presence streptomycin. Most phospholipid increase due an phosphatidylethanolamine. Cyclic depsipeptides not leached from cell streptomycin,...