- Cardiovascular and exercise physiology
- Sports Performance and Training
- Heart Rate Variability and Autonomic Control
- Esophageal and GI Pathology
- Sports Dynamics and Biomechanics
- Cardiovascular Effects of Exercise
- Muscle metabolism and nutrition
- Thermoregulation and physiological responses
- Tracheal and airway disorders
- Sports injuries and prevention
- Renal Transplantation Outcomes and Treatments
- Facial Rejuvenation and Surgery Techniques
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Gastroesophageal reflux and treatments
- Organ and Tissue Transplantation Research
- Transplantation: Methods and Outcomes
- Congenital Diaphragmatic Hernia Studies
- Cardiac Ischemia and Reperfusion
- Surgical Sutures and Adhesives
- High Altitude and Hypoxia
- Exercise and Physiological Responses
- Functional Brain Connectivity Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Diet and metabolism studies
University of Guelph
2017-2024
Mitacs
2023
Boston Children's Hospital
2021-2022
Boston Children's Museum
2022
Health First
2021
Harvard University
2021
University of California, Davis
2019
David Grant USAF Medical Center
2019
UC Davis Health System
2019
Primary Children's Hospital
2019
Rationale: Extracorporeal membrane oxygenation (ECMO) is increasingly used to bridge children who are wait-listed and failing conventional respiratory support for lung transplantation. Objectives: To compare in-hospital mortality a composite outcome of 1-year or retransplantation in bridged with ECMO, supported mechanical ventilation (MV), given neither support. Methods: The United Network Organ Sharing was analyze transplant recipients aged ⩽20 years from January 2004 August 2019....
To characterize and compare female ice hockey players' peak skating speed acceleration ability during linear sprints gameplay. We also sought to quantify the time spent at various speeds frequency of accelerations different thresholds games.
Abstract Aim Assess the effect of low‐ and high‐volume blood flow restriction training (BFR) on maximal aerobic capacity (VO 2 max) determine if alteration in VO max is mediated through changes hemoglobin mass (Hbmass) volume. Methods Participants' Hb (CO‐rebreathe), single, double‐leg volume regulating hormonal responses (renin copeptin) were measured before after BFR training. Training consisted treadmill walking either (1) twice‐daily for 4week (CON HV ) or (2) twice‐weekly 6week (BFR LV...
Thompson, KM, Safadie, A, Ford, J, and Burr, JF. Off-ice resisted sprints best predict all-out skating performance in varsity hockey players. J Strength Cond Res 36(9): 2597-2601, 2022-Off-ice fitness testing is commonly used to the physiological abilities of ice-hockey Although there a notable association between certain off-ice tests jump power anaerobic capacity with on-ice acceleration ( r = 0.3-0.7), it likely that which more closely resemble demands will have better predictive ability...
Ischemic preconditioning (IPC) was initially developed to protect the myocardium from ischemia through altered cardiocyte metabolism. Because of observed effects on metabolism and oxygen kinetics, IPC gained interest as a potential ergogenic aid in sports. Limited research evaluating maximal short-duration activities has been performed, existing literature, mixed outcomes resulting intrasubject variation may have clouded efficacy this technique for enhancing sprint performance. Therefore,...
Abstract Purpose The purpose of the study was to investigate whether carbohydrate utilization is altered during exercise in overreached endurance athletes and examine utility continuous glucose monitors (CGM) detect overreaching status. Methods Eleven (M:8, F:3) completed a 5‐week training block consisting 1 week reduced (PRE), 3 weeks high‐intensity overload (POST), recovery (REC). Participants Lamberts Lambert Submaximal Cycling Test (LSCT) 5 km time‐trial at PRE, POST, REC time points, 15...
This study aimed to explore the potential impact of incorporating blood flow restriction (BFR) training within a block characterized by minimal high-intensity work on 2000-m rowing ergometer time trial (TT) performance in elite/world-class rowers. Physiological markers often associated with endurance (maximal aerobic capacity, V̇O 2max ; lactate thresholds and hemoglobin mass, Hb mass ) were measured determine whether changes are related an improvement performance.
This study sought to assess the reliability and comparability of two custom-built isokinetic dynamometers (Model A Model B) with gold-standard (Humac Norm). The consisted commercially available leg extension machines attached a robotically controlled resistance device (1080 Quantum), able measure power, force velocity outputs. Twenty subjects (14m/6f, 26±4.8yr, 176±7cm, 74.4±12.4kg) performed concentric extensions on Humac Norm. Fifteen maximal were each at 180° s-1, or linear equivalent...
ABSTRACT Purpose The purpose of this study is to characterize both the efficacy altered restriction pressures and consequences optimized blood flow (BFR) for altering cardiovascular fluid regulating response in humans. Methods This work comprised a series related trials. Phase 1: during semi-recumbent cycling (5 min, 60 W) with BFR at 0%, 50%, 75%, 100%, 125% participants’ lowest arterial occlusion pressure (LOP) echocardiographic images were collected alongside continuous heart rate (HR)...
The muscle mechanoreflex may be sensitized by metabolites during exercise. We show that cardiovascular responses to combined (passive cycling) and metaboreflex (postexercise circulatory occlusion) activation are primarily additive do not differ between males females, or across variations in sex hormones females. Our findings provide new insight into the contributions of mechanoreflex-metaboreflex interactions as a cause for prior reports females have smaller blood pressure voluntary
Abstract Thompson, K, Whinton, AK, Ferth, S, Spriet, LL, and Burr, JF. Moderate load resisted sprints do not improve subsequent sprint performance in varsity-level sprinters. J Strength Cond Res 35(1): 72–77, 2021—Resisted training (RST) is commonly used for enhancement athletics team sports to develop acceleration ability. Evidence suggests that RST may be effective as a short-term intervention successive sprints. Although these improvements have been measured sport athletes, limited...
BACKGROUND There is wide variability of transfusion practices for children with hemorrhagic injuries across trauma centers. We are planning a multicenter, randomized clinical trial evaluating tranexamic acid in hemorrhage. Standardization sites important to minimize confounding. Therefore, we sought generate consensus-based guidelines the trial. METHODS used modified Delphi process utilizing multi-site, multi-disciplinary panel experts develop our guidelines. A survey 23 categories on...
Objective: Recovery of function after early brain injury depends upon both reparative and compensatory processes that are minimally understood. Using functional magnetic resonance imaging (fMRI), this study investigated the reorganization hemispheric activity a 24 year old male who suffered right prefrontal cortex damage at 7 years age related to ruptured arteriovenous malformation. His pattern recovery has been examined tracked over past 17 evolved from initial significant impairments in...
Purpose: To provide a robust, efficient synthesis of the malaria drug piperaquine for potential use in resource-poor settings.Methods: We used in-process analytical technologies (IPAT; HPLC) and program experiments to develop that avoids presence toxic impurity API is optimized overall yield operational simplicity.Results : A green-chemical described proceeds 92 – 93 % yield. The chemistry robust provides very pure tetraphosphate salt (> 99.5 %). process utilizes modest amounts (about 8...
ABSTRACT Cardiac output (Q̇ C ) and leg blood flow LEG can be measured simultaneously with high accuracy using transpulmonary femoral vein thermodilution a single‐bolus injection. The invasive measure has offered important insight into hemodynamics distribution during exercise. Despite being the natural modality of exercise in humans, there been no direct Q̇ while running humans. We sought to determine feasibility technique for measuring conductance high‐intensity running, an exploratory...
Along with past performance, professional teams consider physical fitness and physiological potential in determining the value of prospective draft picks. The National Hockey League (NHL) Combine results have been examined for their ability to predict order, but not bona fide hockey performance. Therefore, we sought identify relationships combine test short- long-term NHL performance.During testing (1994-2007), a standardized battery tests was conducted. Player performance (1995-2020)...
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