A5074203774- Merger and Competition Analysis
- Corporate Governance and Law
- Global trade and economics
- ICT Impact and Policies
- Local Government Finance and Decentralization
- World Trade Organization Law
- Auction Theory and Applications
- Groundwater and Isotope Geochemistry
- Crystallization and Solubility Studies
- Climate Change and Health Impacts
- Stress Responses and Cortisol
- X-ray Diffraction in Crystallography
- Fiscal Policy and Economic Growth
- Transport and Economic Policies
- Isotope Analysis in Ecology
- Membrane Separation Technologies
- Tryptophan and brain disorders
- Corporate Finance and Governance
- Air Quality and Health Impacts
- Nanofluid Flow and Heat Transfer
- Geology and Paleoclimatology Research
- Cleft Lip and Palate Research
- Public-Private Partnership Projects
- Plant Virus Research Studies
- Intellectual Property and Patents
Xuzhou Medical College
2021-2024
Nanjing Medical University
2022-2024
State Key Laboratory of Chemical Engineering
2022-2024
Tianjin University
2013-2024
Soochow University
2024
Hebei Medical University
2022-2024
Lanzhou University
2022-2024
Suzhou Guangji Hospital
2024
Soochow University
2024
Southeast University
2024
Abstract In this study, the impact of apolipoprotein B mRNA-editing catalytic subunit-like (APOBEC) enzyme APOBEC3B (A3B) on epidermal growth factor receptor (EGFR)-driven lung cancer was assessed. A3B expression in EGFR mutant (EGFRmut) non-small-cell (NSCLC) mouse models constrained tumorigenesis, while tumors treated with EGFR-targeted therapy associated treatment resistance. Analyses human NSCLC showed upregulation and revealed therapy-induced activation nuclear kappa (NF-κB) as an...
Nanofiltration (NF) has the potential to achieve precise ion–ion separation at subnanometer scale, which is necessary for resource recovery and a circular water economy. Fabricating NF membranes selective ion highly desirable but represents substantial technical challenge. Dipole–dipole interaction mechanism of intermolecular attractions between polar molecules with dipole moment due uneven charge distribution, such an not been leveraged tune membrane structure selectivity. Herein, we...
Real-time and accurate detection of ships plays a vital role in ensuring navigation safety ship supervision. Aiming at the problems large parameters, computation quantity, poor real-time performance, high requirements for memory computing power current model, this paper proposes target algorithm MC-YOLOv5s based on YOLOv5s. First, MobileNetV3-Small lightweight network is used to replace original feature extraction backbone YOLOv5s improve speed algorithm. And then, more efficient CNeB...
Stimulator of interferon genes (STING) activation induces type I interferons and pro-inflammatory cytokines which stimulate tumor antigen cross presentation the adaptive immune responses against tumor. The first-generation STING agonists, cyclic di-nucleotide (CDN), mimicked endogenous ligand guanosine monophosphate adenosine monophosphate, displayed limited clinical efficacy. Here we report discovery SHR1032, a novel small molecule non-CDN agonist. Compared to CDN agonist ADU-S100, SHR1032...
China, like a number of other antitrust jurisdictions, has law concerning unfair pricing. This article develops an economic framework for applying the pricing in China. The draws on experience courts and competition authorities jurisdictions writings various commentators, particularly economists, those jurisdictions. It shows that virtually all have decided to consider claims only exceptional circumstances, rarely, if ever, innovation-intensive industries. For cases pass this screen receive...
Rose (Rosa sp.) flowers have a rich diversity of colors resulting from the differential accumulation anthocyanins, flavonols, and carotenoids. However, genetic molecular determinants red-petal trait in roses remains poorly understood. Here we report that transposable element-like insertion (Rosa1) into RcMYB114, R2R3-MYB transcription factor's promoter region causes its transcription, red petals. In varieties, RcMYB114 is expressed specifically flower organs, but absent non-red varieties....
In plant‐virus disease epidemiology, dynamical models have invariably incorporated a bilinear inoculation rate that is directly proportional to both the abundance of healthy (susceptible) hosts and infective vectors. Similarly, acquisition usually assumed be nonviruliferous vectors infectious hosts. These assumptions been questioned for certain human diseases, infection rates incorporate power parameters variables proposed. Here, diseases are more general form than familiar terms examined....
Many virus diseases of plants are caused by a synergistic interaction between viruses within the host plant. Such synergism can induce symptoms more severe than would be additive effects. In interaction, titre both, one, or neither may enhanced and, as consequence, rate disease spread affected. An epidemiological model was developed in which transmission and loss rates were attributed to different infection possibilities. Sharing same population implies competition, this imposes an increased...
The Weishan REE deposit is located at the eastern part of North China Craton (NCC), western Shandong Province. REE-bearing carbonatite occur as veins associated with aegirine syenite. LA-ICP-MS bastnaesite Th-Pb ages (129 Ma) show that formed contemporary Based on petrographic and geochemical characteristics calcite, mainly consists Generation-1 igneous calcite (G-1 calcite) a small amount Generation-2 hydrothermal (G-2 calcite). Furthermore, apatite characterized by high Sr, LREE low Y...
Multimodal signaling is nearly ubiquitous across animal taxa. While much research has focused on male signal production contributing to female mate-choice or preferences, females often give their own multimodal signals during intersexual communication events. components are classified based whether they contain redundant information (e.g., the backup hypothesis) non-redundant multiple messages from perspective of receiver. We investigated role two different vocalizations produced by house...
BACKGROUND Accumulating evidence suggests that the inflammatory cytokine interleukin-6 (IL-6) contributes to pathophysiology of psychiatric disorders. However, there was no study concerning relationship between IL-6 concentrations and clinical features in chronic phase early-onset schizophrenia (EOS). AIM To investigate serum concentration EOS. METHODS We measured Levels from 74 patients with schizophrenia, including 33 age at onset < 21 years (EOS group) 41 ≥ [adult-onset (AOS) group],...
A chromatography-free, asymmetric synthesis of the C2-symmetric P-chiral diphosphine t-Bu-SMS-Phos was developed using a chiral auxiliary-based approach in five steps from auxiliary 36% overall yield. Separtion and recovery were achieved with good yield (97%) to enable recycling auxiliary. An air-stable crystalline form final ligand identified isolation by crystallization avoid chromatography. This synthetic route applied prepare up 4 kg ligand. The utility this material demonstrated...
This study aimed to examine the association of late bedtime and fast eating speed, both individually interactively, in predicting overweight obesity Chinese preschool-aged children.This was a crosssectional survey among children aged 3-6 years.Overweight is defined according WHO, IOTF, China criteria, respectively.Total 1123 were analyzed.After multivariable adjustment, after 11:00 pm speed increased risk significantly under WHO (odds ratio [OR]=1.92and 1.37, 95% confidence interval [CI]:...
Abstract Background X chromosome inactivation (XCI) is the mechanism by which X-linked gene dosage adjusted between sexes. Evidence shows that many sex-specific diseases have their basis in biology. While female schizophrenia patients often a delayed age of disease onset and clinical phenotypes are different from those males, it unknown whether sex differences associated with choice silencing cells. Previous studies demonstrated aneuploidies may be related to pathogeneses some psychiatric...