A5062024624- Carcinogens and Genotoxicity Assessment
- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Free Radicals and Antioxidants
- Computational Drug Discovery Methods
- Smoking Behavior and Cessation
- Radiation Effects and Dosimetry
- DNA Repair Mechanisms
- Indoor Air Quality and Microbial Exposure
- Platelet Disorders and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hemophilia Treatment and Research
- Health, Environment, Cognitive Aging
- Pharmaceutical and Antibiotic Environmental Impacts
- Effects of Radiation Exposure
- Blood properties and coagulation
- Alzheimer's disease research and treatments
- Animal testing and alternatives
- Environmental Toxicology and Ecotoxicology
- Chemical Safety and Risk Management
- Pesticide Exposure and Toxicity
- Glutathione Transferases and Polymorphisms
- Healthcare cost, quality, practices
- Advanced Chemical Sensor Technologies
Brain Mapping Foundation
2020-2024
Albemarle (United States)
2011-2021
University of Mobile
2020
Florida State University-Panama
2016-2019
Florida State University
1984-2019
University of North Carolina at Chapel Hill
1986-2011
University of South Florida
2011
Institute of Environmental Protection
2011
Marine Polymer Technologies (United States)
2011
Committee on Publication Ethics
2011
Bioconcentration refers to the process of uptake and buildup chemicals in living organisms. Experimental measurement bioconcentration factor (BCF) is time-consuming expensive, not feasible for a large number regulatory concern. Quantitative structure–activity relationship (QSAR) models are used estimating BCF values help risk assessment chemical. This paper presents results QSAR study conducted address an important problem encountered prediction highly hydrophobic chemicals. A new model...
The reported risk factors for glioblastoma (GBM), i.e., ionizing radiation, Li-Fraumeni syndrome, Neurofibromatosis I, and Turcot also increase the of other brain tumor types. Risk human GBM are associated with different oncogenic mutation profiles. Pedigreed domestic dogs a shorter nose flatter face (brachycephalic dogs) display relatively high rates glioma formation. genetic profiles canine gliomas idiosyncratic. association putatively mutational patterns in humans canines suggests that...
Cigarette mainstream smoke (MS) contains a number of structurally diverse substituted phenols. Recent quantitative structure activity relationship (QSAR) studies on phenols show that with electron-releasing groups can form potentially toxic phenoxyl-free radicals. In contrast, electron-withdrawing do not radicals but exert their toxicity primarily through lipophilicity. The chemical structures 253 different reported in MS have been described sufficient detail to allow identification the...
Epidemiological evidence of an association between exposure to chemical carcinogens and increased risk for development glioblastoma (GBM) is limited weak statistical associations in cohorts firefighters, farmers, residents exposed air pollution, soldiers toxic chemicals (e.g., military burn pits, oil-well fire smoke). A history ionizing radiation therapy the head or neck associated with GBM. Ionizing induces point mutations, frameshift double-strand breaks, chromosomal insertions deletions....
It is well established that platelets and the intrinsic plasma coagulation pathway can be activated when blood contacts artificial surfaces. Experiments were performed to assess effect of hemostatic poly-N-acetyl glucosamine (pGlcNAc) nanofibers on red cells. The pGlcNAc nanofibers, isolated from a marine diatom, interact with cells (RBCs) produce stomatocytes. stomatocytes could converted echinocytes by treatment echinocytic reagents, as measured electron microscopy. Electrophoretic Western...
The immobility of plants exerted evolutionary selection pressures resulting in the production thousands chemical substances thought to function as pesticides against predation by insects and animals. More than 10,000 plant-derived compounds have been isolated with existence about 100,000 such postulated. In 1990, Ames et al. reported that 99.99% weight ingested a normal human diet are derived from natural plant-based sources. This surprising result raised question whether these plant were...