Objectives To provide a map of Anatomical Therapeutic Chemical (ATC) Classification System codes to individual Rx-Risk comorbidities and validate the Comorbidity Index. Design The 46 in Index were mapped dispensing’s indicative each condition using ATC codes. Prescription dispensing claims 2014 used calculate Rx-Risk. A baseline logistic regression model was fitted age gender as covariates. added base an (1) unweighted score, (2) weighted score (3) comorbidity categories indicating presence...

In Brief Objective: The aim of this pilot study was to assess any trends related the timing initiation, and duration, hormone therapy (HT) use on cognitive function facilitate design power calculations for a future large cohort entitled Research into Memory, Brain Estrogen Replacement (REMEMBER). Design: A total 428 women aged older than 60 years were recruited from computer-generated random selection Adelaide households. Demographic lifestyle characteristics, HT history recorded confirmed....

Objectives To identify the association between use of multiple anticholinergic medications and risk hospitalization for confusion or dementia. Design Retrospective cohort study conducted over 2 years July 2010 June 2012, using administrative claims data from Australian Department Veterans' Affairs. Setting Australia. Participants veterans dispensed at least one moderately highly medication in year before start. Measurements Cumulative on each day period was determined. The dementia number...

Randomized controlled trials have demonstrated that collaborative medication reviews can improve outcomes for patients with heart failure. We aimed to determine whether these results translated into Australian practice, where are nationally funded.This retrospective cohort study using administrative claims data included veterans 65 years and older receiving bisoprolol, carvedilol, or metoprolol succinate which prescribing physicians indicated treatment was compared those exposed a general...

<h3>Objectives</h3> To determine the impact of comorbid chronic diseases on mortality in older people. <h3>Design</h3> Prospective cohort study (1992–2006). Associations between numbers or mutually exclusive over 14 years, by Cox proportional hazards model adjusting for sociodemographic variables Kaplan–Meier analyses, respectively. <h3>Setting</h3> Population based, Australia. <h3>Participants</h3> 2087 randomly selected participants aged ≥65 years old, living community institutions....

To determine the validity of two medication‐based co‐morbidity indices, Medicines Disease Burden Index (MDBI) and Rx‐Risk‐V in Australian elderly population. In Phase I, sensitivity specificity both indices were determined 767 respondents from wave 6 Longitudinal Study Ageing (ALSA). Medication‐defined index disease categories compared to self‐reported medical conditions. Correlation with self‐rated health was examined Cox proportional hazards models used assess predictive for mortality. II...

To identify the prevalence of potentially preventable medication-related hospitalizations amongst elderly Australian veterans by applying clinical indicators to administrative claims data. Retrospective cohort study in veteran population from 1 January 2004 31 December 2008. A total 109 044 with one or more defined indicator set, during 5-year period. The as a proportion all set. During period, there were 630 008 hospital admissions which 216 527 (13.3%) for conditions set veterans. overall...

Unintended bleeds are a common complication of warfarin therapy. We aimed to determine the impact general practitioner-pharmacist collaborative medication reviews in practice setting on hospitalization-associated patients warfarin.We undertook retrospective cohort study using administrative claims data for ambulatory veteran and war widow population, Australia. Participants were veterans, widows their dependents aged 65 years over dispensed warfarin. The exposed groups those practitioner...

A bstract Background: Diabetes is an increasing problem in Myanmar with more than three million people affected. There are no data on awareness of diabetic retinopathy among the general practitioners (GPs) or population Myanmar. This study aims to evaluate diabetes‐related eye disease GPs and patients Yangon, Design: cross‐sectional survey. Methods: From Medical Association Registry 978 practicing 200 were randomly selected a structured questionnaire was sent each. Each GP asked give...

ABSTRACT Purpose Warfarin management in the elderly population is complex as medicines prescribed for concomitant diseases may further increase risk of major bleeding associated with warfarin use. We aimed to quantify excess bleeding‐related hospitalisation when was co‐dispensed potentially interacting medicines. Methods A retrospective cohort study undertaken over a 4‐year period from July 2002 June 2006 examine medications co‐administered patients taking using an administrative claims...

Abstract Background The Australian Government Department of Veterans’ Affairs (DVA) funds an ongoing health promotion based program to improve use medicines and related services, which implements interventions that include audit feedback in the form patient-specific generated from administrative claims records. We aimed determine changes medicine as a result program. Methods provides targeted medical practitioners. is supported with educational material developed by clinical panel, subject...

Little is known about the impact of taking multiple psychoactive medicines on risk hospitalization for falls.To identify association between medicine use and falls.A retrospective cohort study was conducted July 2011 June 2012 in Australian veteran population who had been dispensed at least one within previous year. Psychoactive with sedative properties included antipsychotics, anxiolytics, hypnotics, antidepressants, opioids, anti-epileptics, anti-Parkinson migraine. The associations falls...

To evaluate the impact of national multifaceted initiatives to improve use proton pump inhibitors (PPIs) on PPIs among older Australians.Interrupted time series analysis using administrative health claims data from Australian Government Department Veterans' Affairs (DVA).Australia.All veterans and dependents who received between January 2003 December 2013.National, interventions PPI were conducted by MATES programme Australia's NPS MedicineWise in April 2004, June 2006, May 2009 August...

Enhanced communication and transfer of information between healthcare providers settings can reduce medication errors post-hospital discharge. The timeframes within which patients access community discharge are not well studied. This study aimed to determine length time from hospital until a general practice, pharmacy or specialist visit, care planning service. We conducted retrospective analysis Department Veterans' Affairs health claims data. All 109 860 veterans hospitalized in 2006 were...

Background This study assessed whether the number of comorbid conditions unrelated to diabetes was associated with a delay in therapeutic progression treatment Australian veterans. Methodology/Principal Findings A retrospective cohort undertaken using data from Department Veterans' Affairs (DVA) claims database between July 2000 and June 2008. The included new users metformin or sulfonylurea medicines. outcome time addition switch another antidiabetic treatment. total identified...

Objective To determine time to opioid cessation post discharge from hospital in persons who had been admitted for a surgical procedure and were previously naïve opioids. Design, setting participants Retrospective cohort study using administrative health claims database the Australian Government Department of Veterans’ Affairs (DVA). DVA gold card holders aged between 18 100 years admission 1 January 2014 30 December 2015 therapy prior included study. Gold are eligible all services that...

We investigated the quality of primary care asthma management in a sample Australian general practices.247 practitioners (GPs) from 97 practices completed structured interview about asthma, diabetes and hypertension/heart disease. A further with senior practice principal manager was used to collect information capacity for chronic disease management.Just under half GPs (47%) had access an register majority (76%) spirometry their practice. In terms routine 12% reported using routinely, 13%...

The Patient Participation Program (PPP) was a patient satisfaction survey endorsed by the Royal Australian College of General Practitioners and designed to assist general practitioners in continuous quality improvement (CQI). been undertaken 3500 practices over million patients between 1994 2003. This study aimed use pooled questionnaire data investigate changes with primary care time. results 10 years PPP surveys were analyzed respect variables including year completion, age, gender,...

Objective: To determine whether proton-pump inhibitor (PPI) use is associated with hospitalisations for pneumonia and antibiotic use. Design setting: Historical cohort study in the Australian veteran population, conducted from 1 January 2002 to 30 December 2006, comparing veterans exposed PPIs those not exposed. Participants: All 185 533 who were Gold Card holders (ie, eligible all health services subsidised by Department of Veterans' Affairs) aged 65 years over at had been prescribed least...

ABSTRACT Background: Depression is one of the leading contributors to burden non-fatal diseases in Australia. Although there an overall increasing trend antidepressant use, relationship between use antidepressants and depressive symptomatology not clear, particularly older population. Methods: Data for this study were obtained from Australian Longitudinal Study Ageing (ALSA), a cohort 2087 people aged over 65 years at baseline. Four waves home interviews conducted 1992 2004 collect...

To compare the results of a new-user cohort study design and self-controlled case series (SCCS) using risk hospitalisation for pneumonia in those dispensed proton pump inhibitors compared to unexposed as study. The Australian Government Department Veterans' Affairs administrative claims database was used. Exposure hospitalisations were identified over 4 year period 01 Jul 2007 -30 Jun 2011. same inclusion exclusion criteria applied both studies, however, SCCS included subjects with least one...

Introduction . Ophthalmic timolol, a topical nonselective beta-blocker, has the potential to be absorbed systemically which may cause adverse cardiovascular effects. This study was conducted determine whether initiation of ophthalmic timolol associated with an increased risk hospitalisation for bradycardia. Materials and Methods A self-controlled case-series undertaken in patients who were hospitalised bradycardia exposed timolol. Person-time after partitioned into periods: 1–30 days, 31–180...