A5066986626- Emergency and Acute Care Studies
- Renal Diseases and Glomerulopathies
- Trauma and Emergency Care Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Disaster Response and Management
- Neonatal Respiratory Health Research
- Intensive Care Unit Cognitive Disorders
- Prostate Cancer Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Pneumonia and Respiratory Infections
- Methemoglobinemia and Tumor Lysis Syndrome
- Pediatric Urology and Nephrology Studies
- Colorectal Cancer Screening and Detection
- Family and Patient Care in Intensive Care Units
- Urinary Tract Infections Management
- Respiratory Support and Mechanisms
- COVID-19 and Mental Health
- Radiomics and Machine Learning in Medical Imaging
- Central Venous Catheters and Hemodialysis
- Creativity in Education and Neuroscience
- Chronic Lymphocytic Leukemia Research
- Bacterial Infections and Vaccines
- Malaria Research and Control
- Neuroscience, Education and Cognitive Function
- COVID-19 and healthcare impacts
Imperial College Healthcare NHS Trust
2016-2025
Hammersmith Hospital
2019-2025
Bristol Royal Hospital for Children
2020-2023
Imperial College London
2021-2023
University of the West of England
2022
National Health Service
2019
John Radcliffe Hospital
2014
University of Oxford
2009-2014
Cheltenham General Hospital
2013
Significance Statement Social distancing is an important tool in preventing the spread of SARS-CoV-2 during COVID-19 pandemic. Dialysis centers that treat patients undergoing hemodialysis typically are not conducive to social distancing, and there limited published experience available for guidance. The authors describe control measures—including universal protective equipment, a regular screening process, case isolation—implemented rapidly developing epidemic large dialysis center, as well...
Summary This guideline provides consensus opinion on the investigations required for people presenting with suspected monoclonal gammopathy of renal significance to both nephrology and haematology physicians. The discusses principles treating a patient MGRS recommendations supportive management haematological therapy. It details recommended on‐going monitoring specialty areas.
Visual Abstract Export Background and objectives Central venous catheters have traditionally provided access for urgent hemodialysis, but are also sometimes advocated as an option older or more comorbid patients. Adverse effects of this type dialysis include central stenosis, which the risk factors consequences incompletely understood. Design, setting, participants, & measurements We conducted two studies within same population cohort, comprising all patients starting hemodialysis in a...
Bacterial conjugate vaccines have dramatically changed the epidemiology of childhood meningitis; viral causes are increasingly predominant, but current UK is unknown. This prospective study recruited children under 16 years age admitted to 3 hospitals with suspected meningitis. 70/388 had meningitis—13 bacterial, 26 and 29 no pathogen identified. Group B Streptococcus was most common bacterial pathogen. Infants months meningitis were more likely a reduced Glasgow Coma Score respiratory...
ABSTRACT Background Light chain proximal tubulopathy (LCPT) is a rare form of paraprotein-related disease, occurring in two main histopathological forms: crystalline and non-crystalline. The clinicopathological features, treatment strategies outcomes, especially the non-crystalline form, are not well described. Methods We conducted single-centre retrospective case series 12 LCPT patients, 5 7 non-crystalline, between 2005 2021. Results median age was 69.5 years (range 47–80). Ten patients...
Previous studies in adult congenital heart disease (CHD) have demonstrated a link between renal dysfunction and mortality. However, the prognostic significance of CHD decompensated failure (HF) remains unclear. We sought to assess association outcomes adults with presenting our centre acute HF 2010 2021. This retrospective analysis focused on dysfunction, pre-existing admission, during after index hospitalization. Chronic kidney (CKD) was defined as an estimated glomerular filtration rate...
ABSTRACT Background Paediatric attendances to Emergency Departments (EDs) in the UK are increasing, particularly for younger children. Neonates present a challenge due their non-specific presentations. Community services under increasing pressure and parents may preferentially bring children ED, even non-urgent problems. Neonatal have not been extensively studied, but previous reviews shown many well, often requiring specific medical intervention. This study aimed characterise presenting...
Abstract Aim Attendances to emergency departments (EDs) in the UK are increasing, particularly for younger children. Community services under increasing pressure and parents may preferentially bring their babies ED, even non‐urgent problems. This study aimed characterise presenting features, management disposition of neonatal attendances a children's ED (CED). Methods Retrospective observational review (≤28 days) CED at Bristol Royal Hospital Children (BRHC) from 01/01/2016 31/12/2016....
Microscopy is the gold standard for malaria diagnosis but dependent on trained personnel. Rapid diagnostic tests (RDTs) form mainstay of in endemic areas without access to high-quality microscopy. We aimed evaluate whether RDT alone could rule out imported children presenting UK emergency departments (EDs). UK-based, multi-center, retrospective, accuracy study. Included: any child <16 years ED with history fever and travel a malaria-endemic country, between 01/01/2016 31/12/2017. Diagnosis:...
Triage is key to effective management of major incidents, yet there scarce evidence surrounding the optimal method paediatric incident triage (MIT). This study aimed derive consensus on components MIT among healthcare professionals responsible for during incidents.Two-round online Delphi delivered July 2021-October 2021, including participants from pre-hospital and hospital specialities incidents. A 5-point Likert scale was used determine consensus, set a priori at 70%.111 clinicians...
<h3>Introduction</h3> Non-invasive ventilation (NIV) is an effective treatment for acute type 2 respiratory failure, often avoiding intubation and improving mortality. However many patients struggle to tolerate NIV. There limited understanding of patients’ or their relatives/carers subjective experience As good patient increasingly recognised reflect high-quality care we conducted in-depth experience-based questionnaire aiming identify key concerns patients, relatives/carers, treated with...
ABSTRACT Introduction Triage is a key principle in the effective management of major incidents, yet there paucity evidence surrounding optimal method paediatric incident triage (MIT). This study aimed to derive consensus on components MIT among healthcare professionals involved incidents. Methods modified two-round online Delphi study, delivered between July and October 2021, included participants from pre-hospital hospital specialities managing incident. Statements were derived iteratively...
Masked crystalline light chain tubulopathy and podocytopathy with focal
Historical use of urine varies greatly from the production gunpowder, as a fertiliser, dyeing wool in textile industry and wound healing. The ancient Egyptians used to have pregnant woman urinate on bags wheat barley. if sprouted, it was girl; barley did, boy; neither there no pregnancy! However, Carl Friedrich Gartner (1772–1850) who towards end 18th century pioneered testing at bedside.
<h3>Aims</h3> Triage is a key principle in the effective management of major incidents, yet there paucity evidence surrounding optimal method paediatric incident triage (MIT). This study aimed to derive consensus on components MIT among healthcare professionals involved incidents. <h3>Methods</h3> modified two-round online Delphi study, delivered between July and October 2021, included participants from pre-hospital hospital specialities managing incident. Statements were derived iteratively...