A5101977695- Occupational and environmental lung diseases
- Plant Physiology and Cultivation Studies
- Nanoparticles: synthesis and applications
- Plant Disease Management Techniques
- Asthma and respiratory diseases
- Pleural and Pulmonary Diseases
- Banana Cultivation and Research
- Occupational exposure and asthma
- Functional Brain Connectivity Studies
- Plant tissue culture and regeneration
- Air Quality and Health Impacts
- Anesthesia and Neurotoxicity Research
- Plant Pathogens and Fungal Diseases
- Horticultural and Viticultural Research
- Neural dynamics and brain function
- Ethnobotanical and Medicinal Plants Studies
- Heavy metals in environment
- Environmental Toxicology and Ecotoxicology
- Soil and Environmental Studies
- Bee Products Chemical Analysis
- Aluminum toxicity and tolerance in plants and animals
- Heavy Metals in Plants
- Heavy Metal Exposure and Toxicity
- Plant Ecology and Taxonomy Studies
- Botany, Ecology, and Taxonomy Studies
Nagoya City University
2016-2024
Alexandria University
1982-2024
Radboud University Nijmegen
2024
University of Peshawar
2023
Medical University of Vienna
2023
Ain Shams University
2019-2023
Benha University
2021-2023
Mizuho (Japan)
2018
University of California, Los Angeles
1965-1982
Tanta University
1982
Abstract Multi‐walled carbon nanotube‐7 ( MWCNT ‐7) fibers are biopersistent and have a structure similar to asbestos. ‐7 has been shown induce malignant mesothelioma when administered by intrascrotal or intraperitoneal injection in rats mice, an inhalation study demonstrated that exposed respirable developed lung tumors. ‐N, which is ‐7, was both tumors trans‐tracheal intrapulmonary spraying TIPS ). The present performed investigate the carcinogenicity of method. Ten‐week‐old male F344/Crj...
Abstract Background Multi-walled carbon nanotubes can be divided into two general subtypes: tangled and straight. MWCNT-N (60 nm in diameter) MWCNT-7 (80–90 are straight-type MWCNTs, similarly to asbestos, both carcinogenic the lung pleura when administered rats via airway. Injection of MWCNTs peritoneal cavity also induces development mesothelioma, however, injection tangled-type does not induce carcinogenesis. To investigate these effects we conducted a 2-year comparative study potential...
Apple is an important fruit crop that always in demand due to its commercial and nutraceutical value. Also, the requirement for quality planting material this new plantations increasing continuously. In-vitro propagation alternative approach, which may help produce genetically identical high grade material. In study, first time, efficient reproducible protocol has been established apple root stock MM 104 via axillary bud. Culturing buds on Murashige Skoog rootstock (MM 104) resulted better...
Abstract Background Considering the expanding industrial applications of carbon nanotubes (CNTs), safety assessment these materials is far less than needed. Very few long-term in vivo studies have been carried out. This first 2-year study to assess effects double walled (DWCNTs) lung and pleura rats after pulmonary exposure. Methods Rats were divided into six groups: untreated, Vehicle, 3 DWCNT groups (0.12 mg/rat, 0.25 mg/rat 0.5 mg/rat), MWCNT-7 (0.5 mg/rat). The test administrated by...
Paris polyphylla Smith (Melanthiaceae) family, which is native to the Himalayan region, has received a lot of attention recently due its extensive history usage in traditional medicine. The production steroidal saponin from callus suspension cultures P. was observed current study. study attempted develop plant culture through optimization cultivation technique for suspension, quantification total phenolic components and estimation extract’s antioxidant activity. A light-yellow formed within...
The objective of the present work was to develop and optimize an intranasal in situ gel Pramipexole dihydrochloride for enhanced drug delivery, better patient acceptability, possible proper treatment Parkinson’s disease. Preliminary studies were performed select formulation components identify key variables affecting formulation. optimization gelling system achieved by applying 32 full factorial design using Design-Expert® software (Stat-Ease 9.0.6 version) taking concentrations Poloxamer...
This study was designed to investigate the possibility of cadmium (Cd) induce oxidative stress and biochemical perturbations in Nile tilapia liver gills role Vitamin C (Vit. C) alleviating its toxic effects. fish were randomly divided into four groups thirteen each, group one served as control without any treatment, two exposed Cd (5mg/liter water), three supplemented with vitamin (Vit.C) (500mg/kg diet), plus Vit. C. The exposure caused increase Liver aminotransferases (AST ALT), elevation...
The high incidence of aflatoxins (AFs) in chocolates suggests the necessity to create a practical and cost-effective processing strategy for eliminating mycotoxins. present study aimed assess adsorption abilities activated charcoal (A. charcoal), yeast (Saccharomyces cerevisiae), probiotic Lactobacillus rhamnosus as AFs adsorbents three forms—sole, di- tri-mix—in phosphate-buffered saline (PBS) through an vitro approach, simulated mimic conditions gastrointestinal tract (GIT) based on pH,...
In this study, the effects of subacute Pterocarpus santalinus (rosewood) consumption on lung, brain, stomach, and hematological parameters in Wistar rats were evaluated. Mice both sexes used experiment. Groups 2, 3, 4 given 100, 200, 400 mg/kg red sandalwood, group 1 was distilled water (10 ml/kg). Animals kept standard cages for 28 days extracts taken orally before being weighed sacrificed. Histological analysis performed using hematoxylin eosin (H&E) staining technique. The spleen, stomach...
Detection of meat adulteration is a critical issue in food labeling procedures and serious concern related to fraud, authenticity, religious beliefs. The current work detected quantified raw ground beef with pork, donkey, dog based on fatty acid profiles using GC-MS/MS. study design incorporated or meat; negative positive controls were used for the different species. Results demonstrated several significant differences (p < 0.05) contents between mixed/adulterated pure beef. In addition,...
Very little is known about the in vivo toxicity of inhaled double-walled carbon nanotubes (DWCNTs). In present study, we compared pulmonary DWCNT to MWCNT-7, a well-known multi-walled nanotube. Rats were divided into six groups: untreated, vehicle, low-dose DWCNT, high-dose and MWCNT-7. The test materials administered by intra-tracheal intra-pulmonary spraying (TIPS) every other day for 15 days: groups final total doses 0.25 0.50 mg/rat material. animals sacrificed 1 6 weeks after TIPS...
Potassium octatitanate fibers (K2O•8TiO2, POT fibers) are used as an asbestos substitute. Their physical characteristics suggest that respirable likely to be carcinogenic in the lung and pleura. However, previous 2-year inhalation studies reported respired had little or no potential. In present study ten-week old male F344 rats were left untreated administered vehicle, 0.25 0.5 mg rutile-type nano TiO2 (r-nTiO2), fibers, MWCNT-7 by intra-tracheal intra-pulmonary spraying (TIPS), then...
Potassium octatitanate (K2O·8TiO2, POT) fibers are used as an alternative to asbestos. Their shape and biopersistence suggest that they possibly carcinogenic. However, inhalation studies have shown respired POT little carcinogenic potential. We conducted a short-term study in which we administered fibers, anatase rutile titanium dioxide nanoparticles (a-nTiO2, r-nTiO2) rats using intra-tracheal intra-pulmonary spraying (TIPS). found similarly other materials, were more toxic than non-fibrous...
Background: Despite the beneficial effects of zinc oxide nanoparticles (ZnONPs) on different biomedical applications, including their antioxidant and anti-inflammatory ones, it might have cytotoxic genotoxic impacts male reproductive system. Objective: The current study compares effect bulk form, at doses, rats’ performance, testicular antioxidants, gene expression, histopathology. Materials Methods: Thirty rats were randomly allocated equally in five groups. control one was injected with...
Mimosa caesalpiniifolia (Sansão-do-Campo) is a native species of the caatinga in northeastern Brazil that has been studied for its potential anti-inflammatory and antidepressant activity. It popularly consumed as medicinal plant pharmacological benefits are evidenced literature.
Potassium octatitanate fibers (K 2 O·8TiO , POT fibers) are widely used as an alternative to asbestos. We investigated the pulmonary and pleural toxicity of with reference non‐fibrous titanium dioxide nanoparticles ( nTiO ), photoreactive anatase (a‐ ) inert rutile (r‐ ). Ten‐week‐old male F344 rats were given 0.5 mL 250 μg/ suspensions fibers, a‐ or r‐ 8 times (1 mg/rat) over a 15‐day period by trans‐tracheal intrapulmonary spraying TIPS Rats killed at 6 hours 4 weeks after last dose....
Allergic airway inflammation (AAI) is a chronic respiratory disease that considered severe restriction in daily life and accompanied by constant risk of acute aggravation. It characterized IgE-dependent activation mast cells, infiltration eosinophils, activated T-helper cell type 2 (Th2) lymphocytes into mucosa. Purinergic receptor signaling known to play crucial role inducing maintaining allergic inflammation. Previous studies an ovalbumin (OVA)–alum mouse model demonstrated contribution...
Anemia is a pathological condition characterized by reduced oxygen bioavailability and/or changes in hematological parameters. This study investigated the anti-anemic activities of
A detailed investigation has been carried out to determine, through tissue analysis, the nutritional status of 55 plant species Egyptian wild flora collected from desert area Burg El-Arab, west Alexandria. The data obtained resulted in classifying different into 17 groups, each being specifically rich a given element. relationship between level elements and kind habitats also discussed.
Translocation of multiwalled carbon nanotubes (MWCNTs) from the lung to pleural cavity, deposition fibers in tissue, induction fibrosis, and mesothelial proliferation have been found rodents administered MWCNTs by different pulmonary exposure methods. However, whether translocation subsequent inflammation are associated with lesions is unclear. In present study, male F344 rats were given 250 μg two types MWCNTs, crocidolite as a positive control, 2 times/week for 4 weeks intratracheal...
Abstract Barley plants grown in a soil very low organic matter had higher concentrations of Mn, Cu, Zn, and Mo than when the were considerably matter. Application some heavy metals (Co, W, Ag) resulted much more severe phytotoxicity on high soil. FeDTPA (ferric diethylene triamine pentaacetate acid) increased Fe levels Low lower Cs level from applied Sulfur Mn concentration even though all was not neutralized.
The northeastern corner of the western desert Egypt is characterized by marked topographic, climatic, and soil variations, which have caused formation different habitat types with their own distinct vegetational structures. magnitude differences in edaphic factors among these has been demonstrated ordering them along axes representing important variables. Some ecological attributes perennial shrubs growing at each type were determined nondestructive numerical measurements. mineral element...