A5019022737- Drug-Induced Hepatotoxicity and Protection
- Nigella sativa pharmacological applications
- Heavy Metal Exposure and Toxicity
- Animal Nutrition and Physiology
- Aquaculture disease management and microbiota
- Environmental Toxicology and Ecotoxicology
- Aquaculture Nutrition and Growth
- Pesticide Exposure and Toxicity
- Saffron Plant Research Studies
- Selenium in Biological Systems
- Pharmaceutical and Antibiotic Environmental Impacts
- Ion Transport and Channel Regulation
- Meat and Animal Product Quality
- Insect Pest Control Strategies
- Chemotherapy-induced organ toxicity mitigation
- Trace Elements in Health
- Drug Transport and Resistance Mechanisms
- Nephrotoxicity and Medicinal Plants
- Insect and Pesticide Research
- Extracellular vesicles in disease
- Antibiotics Pharmacokinetics and Efficacy
- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- Bat Biology and Ecology Studies
- Essential Oils and Antimicrobial Activity
Benha University
2016-2025
Penn State Milton S. Hershey Medical Center
2024
Mansoura University
2002-2024
South Valley University
2022-2024
Jilin Agricultural University
2021
University of Miyazaki
2014-2020
Virginia Commonwealth University
2019
Cairo University
1972
Microcystin- (MC-) LR is the most frequent cyanotoxin produced by Microcystis aeruginosa cyanobacteria in contaminated freshwater environment. MC represents a health hazard to humans and animals. Therefore, present study was designed evaluate potential ameliorative effect of thymoquinone (TQ) and/or piperine (PP) against toxicity mice. Fifty-six mice were randomly divided into seven experimental groups. Group I normal control that received distilled water for 21 days; II treated with TQ (10...
CPF (chlorpyrifos) is an organophosphate pesticide used in agricultural and veterinary applications. Our experiment aimed to explore the effects of thymoquinone (TQ) and/or lycopene (LP) against CPF-induced neurotoxicity. Wistar rats were categorized into seven groups: first group served as a control (corn oil only); second group, TQ (10 mg/kg); third LP fourth mg/kg) deemed toxic control; fifth + CPF; sixth (LP CPF); seventh (TQ CPF). intoxication inhibited acetylcholinesterase (AchE),...
The COVID-19 pandemic presents systemic disorders, primarily affecting respiratory and cardiovascular systems. N-acetylcysteine (NAC) possesses antioxidative, anti-inflammatory, immune-modulating properties, suggest-ing a potential therapy against COVID-19. In the current study, meta-analysis was conducted to investigate effectiveness of NAC supplementation A literature search from April 2019 December 2023 using Rev-Man 5.3 incorporating 14 studies with 20,980 participants. Results revealed...
Edible films and coatings offer great potential to support sustainable food production by lowering packaging waste, extending product shelf life, actively preserving quality. Using edible containing plant extracts with antioxidant antibacterial characteristics could help enhance the quality life of fish products. In this study, combination effect chitosan beetroot, curcumin, garlic on biogenic amines (BAs) reduction, biochemical [pH, thiobarbituric acid index (TBA), trimethylamine (TMA),...
Periodontitis is an inflammation-related condition, caused by infectious microbiome and host defense that causes damage to periodontium. The natural processes of the mouth, like saliva production eating, significantly diminish therapeutic medication residency in region periodontal disease. Furthermore, complexity diversity pathological mechanisms make successful periodontitis treatment challenging. As a result, developing enhanced local drug delivery technologies logical therapy procedures...
Piroxicam (PM) is an oxicam-NSAID commonly recommended for various pain and associated inflammatory disorders. However, it reported to have a gastric hepato-renal toxic effect. Therefore, the current research was planned investigate possible mechanisms behind mitigating action of coenzyme (CoQ10), natural, free radical scavenger, against PM tissue injury. Rats were assigned five equal groups; Control, CoQ10 (10 mg/kg, orally), (7 i.p.), CoQ + L, H group. After 28 days, provoked severe...
Gentamicin (GM) is a commonly prescribed antimicrobial drug used for treatment of infections but associated hepatic and renal complications restrict its efficacy. Overproduction free radicals inflammation are involved in GM-induced hepato-renal damage. Date palm renowned to have antioxidant anti-inflammatory bioactive composites. In this context, the current research was purposed assess ameliorative influence date extract (DE) supplementation against injury. Gas chromatography-mass...
World Health Organization classified Listeria monocytogenes as a major notable foodborne pathogen associated with high mortality and hospitalization. The study reports the prevalence, antibiogram, virulence determination genetic characterization of L. from different food products. A total 250 samples, fifty samples each raw milk, ice cream, minced meat, fish fillet sausage were collected Menoufiya governorate in Egypt. was detected 17 (6.8%) tested including meat (14%), (8%), (6%) milk (6%)....
Aflatoxin B1 (AF) is an unavoidable environmental pollutant that contaminates food, feed, and grains, which seriously threatens human animal health. Arabic gum (AG) has recently evoked much attention owing to its promising therapeutic potential. Thus, the current study was conducted look into possible mechanisms beyond ameliorative activity of AG against AF-inflicted hepatic injury. Male Wistar rats were assigned four groups: Control, (7.5 g/kg b.w/day, orally), AF (200 µg/kg b.w), plus...
Deltamethrin (DLM) is a synthetic pyrethroid with anti-acaricide and insecticidal properties. It commonly used in agriculture veterinary medicine. Humans animals are exposed to DLM through the ingestion of polluted food water, resulting severe health issues. N-acetylcysteine (NAC) prodrug L-cysteine, precursor glutathione. can restore oxidant-antioxidant balance. Therefore, this research aimed examine whether NAC may protect broiler chickens against oxidative stress, at level biochemical...
has been the subject of plentiful studies due to its purported health advantages; nevertheless, additional investigation is required determine whether several chronic diseases may be treated or avoided with nanoform. Therefore, we set out examine
Urinary exosomes are nano-sized vesicles secreted into urine from all types of renal epithelial cells and known to contain possible biomarker proteins for diseases. Gentamicin has been reported decrease the level aquaporin (AQP)2, which is be mainly expressed in collecting ducts excreted via exosomes. In present study, we investigated whether urinary exosomal AQP2 could serve as a potential gentamicin-induced nephrotoxicity, especially duct cell dysfunction. was given rats intraperitoneally...