A5103284325- Health, Nursing, Elderly Care
- Ocular Diseases and Behçet’s Syndrome
- Business and Management Studies
- Systemic Lupus Erythematosus Research
- Retinal and Optic Conditions
- Education and Public Policy
- Spondyloarthritis Studies and Treatments
- Vasculitis and related conditions
- Tryptophan and brain disorders
- Bone health and treatments
- COVID-19 Clinical Research Studies
- Bipolar Disorder and Treatment
- Inflammasome and immune disorders
- SARS-CoV-2 and COVID-19 Research
- Psoriasis: Treatment and Pathogenesis
- Salivary Gland Disorders and Functions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoidosis and Beryllium Toxicity Research
- Palliative and Oncologic Care
- Rheumatoid Arthritis Research and Therapies
- Youth, Drugs, and Violence
- Maternal and Neonatal Healthcare
- Healthcare Regulation
- Otitis Media and Relapsing Polychondritis
- Bone and Joint Diseases
Universidade Federal de Santa Catarina
2013-2024
Polydoro Ernani de São Thiago University Hospital
2013-2017
Centro Universitário Una
2016
Universidade Federal de Minas Gerais
2006-2015
Governador Celso Ramos Hospital
2009-2012
Universidade de São Paulo
2006-2011
Prefeitura Municipal de Belo Horizonte
2008
Faculdade de Ciências Médicas de Minas Gerais
2007
Abstract The serotonin transporter gene has a 44 bp insertion/deletion polymorphism within the promoter region ( 5‐HTTLPR ) with two allelic forms, long (L) and short (S) variants. Association between low‐activity S variant bipolar disorder (BPD) been shown but its replication not consistent. It also described as an association allele suicidal behavior. Since behavior is rather frequent event in BPD, important question whether suicidality, instead of bipolarity itself, could be related to...
We tested the hypothesis that presence of AKT1 and AKTIP polymorphisms, target genes encode key proteins in signaling dopaminergic serotonergic systems, is associated with suicidal behavior bipolar patients. The subjects were 273 patients diagnosed disorder I or II (age = 41.4 ± 12.9). TaqMan single‐nucleotide polymorphism genotyping assays ( : rs2494731, rs3803304, rs3730358, rs10149779, rs2494746, rs1130214 rs249878; rs9302648 rs7189819) used. found marker showed an association suicide...
Abstract Aim: To investigate serum levels of tumor markers in patients with rheumatoid arthritis (RA) and their association disease activity or the presence cancer. Method: We performed an observational cohort study including 100 RA control subjects. Serum carcinoembryonic antigen (CEA), cancer (CA) 125, CA 19–9 15–3 were evaluated along clinical laboratorial data. Association tests between parameters performed. Patients abnormal submitted to further investigation, chest X‐ray, colonoscopy,...
O objetivo deste estudo é descrever as características clínicas e respostas às intervenções terapêuticas, incluindo a terapia antifator de necrose tumoral (TNF), em uma série casos brasileiros arterite Takayasu (AT). Foi realizado um observacional, retrospectivo, com base na revisão prontuários, todos os pacientes AT, acordo critérios classificação do American College of Rheumatology, acompanhamento no Serviço Reumatologia Hospital Universitário da Universidade Federal Santa Catarina (UFSC),...
Hypertrophic osteoarthropathy (HOA) is characterized by periostitis of tubular bones, thickened skin, and digital clubbing. Its pathogenesis unknown but an inflammatory factor increased bone remodeling have been implicated. It a very rare disease, usually diagnosed late with few therapeutic options. Bone joint pains are secondary to difficult control. Tumor necrosis factor-alpha cytokine that induces other production, has osteoclastogenic effect in different rheumatic diseases probably also...
Some studies have reported that adding leflunomide (LEF) to the treatment of rheumatoid arthritis (RA) in patients who do not respond methotrexate (MTX) improved efficacy but increased risk liver toxicity. This study aimed at assessing incidence toxicity with active RA using LEF and MTX combination therapy comparison on monotherapy.Between February September 2009, 97 consecutive followed up University Hospital Universidade Federal de Santa Catarina, Brazil, were enrolled. alone or had their...
Chronic use of cocaine by inhalation may induce midline destructive lesions (CIMDL), which can sometimes be difficult to distinguish from the ear, nose and throat Wegener's Granulomatosis (WG). We describe case a 43-year-old female patient admitted with two-year history nasal obstruction rhinorrhea. She had been diagnosed WG for five months, being on prednisone cyclophosphamide. On her physical examination, perforation septum palate was observed. Laboratory tests showed elevated acute phase...