Joon Pyung Seo

ORCID: 0000-0002-8729-7868
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About
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Research Areas
  • Hepatitis B Virus Studies
  • Ultrasound and Hyperthermia Applications
  • Viral gastroenteritis research and epidemiology
  • Hepatitis C virus research
  • Microfluidic and Bio-sensing Technologies
  • Liver Disease Diagnosis and Treatment
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Healthcare and Venom Research
  • Hepatitis Viruses Studies and Epidemiology
  • Neuroscience and Neural Engineering
  • Cardiovascular Function and Risk Factors
  • Photoreceptor and optogenetics research
  • Ultrasound Imaging and Elastography
  • Gene expression and cancer classification
  • Neurological disorders and treatments
  • Heat shock proteins research
  • Connexins and lens biology

Rice University
2023-2024

Konkuk University Medical Center
2024

Seoul National University
2002-2019

Gene expression is a critical component of brain physiology, but monitoring this in the living represents major challenge. Here, we introduce new paradigm called recovery markers through insonation (REMIS) for noninvasive measurement gene with cell type, spatial, and temporal specificity. Our approach relies on engineered protein that are produced neurons exit into brain’s interstitium. When ultrasound applied to targeted regions, it opens blood-brain barrier releases these bloodstream. Once...

10.1126/sciadv.adj7686 article EN cc-by-nc Science Advances 2024-08-07

Blood tests are among the most common clinical tools due to their low cost, simplicity, and ability observe many markers at once. However, currently, blood can only monitor a fraction of physiological processes that happen have serum marker. Here, we will present our work on development synthetic track gene expression in intact brain cells with simple test. The marker approach has several advantages. First, detection existing may be challenging levels blood. With marker, one design reporter...

10.1121/10.0026652 article EN The Journal of the Acoustical Society of America 2024-03-01

Abstract Background High-performance liquid chromatography (HPLC) is widely used as a HbA1c routine assay. However, quantification of glycated hemoglobin (HbA1c) challenge in patients with (Hb) variants. In this study, we evaluated the clinical utility and analytical performance new developed ARKRAY ADMAS HA-8190V assay using autoswitch mode, that automatically switches between variant fast mode depending on patient Hb characteristics, suspected Korea. Methods The measuring time for was...

10.1093/clinchem/hvae106.052 article EN Clinical Chemistry 2024-10-01

Gene expression is a critical component of brain physiology and activity, but monitoring this in the living represents significant challenge. Here, we introduce new paradigm called Recovery Markers through InSonation (REMIS) for noninvasive measurement gene with cell-type, spatial, temporal specificity. Our approach relies on engineered protein markers that are designed to be expressed neurons exit into interstitium. By applying ultrasound targeted regions, these released bloodstream, where...

10.1101/2023.05.23.541868 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-05-24

ABSTRACT The brain is comprised of multiple regions performing distinct functions. Within each these regions, there are cell types that can affect physiology. Finally, within signaling pathways, that, when activated or inhibited, control the cell’s activity, and consequently function. For reasons, methods with regional, cell-type, molecular precision have been widely used in neuroscience. However, so far, achieving sustained over a region level specificity relied either on gene delivery...

10.1101/2023.10.12.562069 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-10-16
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