- Metabolism and Genetic Disorders
- Neonatal Health and Biochemistry
- Folate and B Vitamins Research
- Biochemical and Molecular Research
- Amino Acid Enzymes and Metabolism
- Mitochondrial Function and Pathology
- Diet and metabolism studies
- Biotin and Related Studies
- Click Chemistry and Applications
- Child Nutrition and Water Access
- Lysosomal Storage Disorders Research
- Trace Elements in Health
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Biomedical Research and Pathophysiology
- Glycogen Storage Diseases and Myoclonus
- Neuroscience of respiration and sleep
- Advanced biosensing and bioanalysis techniques
- Neonatal Respiratory Health Research
- Muscle metabolism and nutrition
- Diet, Metabolism, and Disease
- Peroxisome Proliferator-Activated Receptors
- RNA regulation and disease
- Molecular Junctions and Nanostructures
- Lipid metabolism and disorders
- Plant Micronutrient Interactions and Effects
Hacettepe University
1994-2022
Hacettepe University Hospital
1990-1999
Virginia Commonwealth University Medical Center
1998
Uniwersytecki Szpital Dziecięcy
1992
Etimesgut Asker Hastanesi
1988
Massachusetts Institute of Technology
1971-1972
<h3>Abstract</h3> <h3>Background</h3> Genomic instability promotes evolution and heterogeneity of tumors. Unraveling its mechanistic basis is essential to design appropriate therapeutic strategies. In a recent study we reported an unexpected oncogenic property p21<sup>WAF1/Cip1</sup> showing that chronic expression, in p53-deficient environment, causes genomic by deregulating the replication licensing machinery. <h3>Results</h3> Extending on this work now demonstrate can further fuel...
Zinc deficiency has been seen in developing countries which grain-based vegetable protein is consumed more often than animal protein. This study was done to emphasize the importance of zinc-fortified foods and investigate bioavailability zinc bread.Serum concentrations healthy 7- 11-year-old school children were determined. In 24 101 serum below 65 micrograms/ul. These with asymptomatic divided into two equal groups. The 12 low received bread providing 2 mg/kg/day elemental acetate for 90...
Sanfilippo syndrome (mucopolysaccharidosis type III, MPS III) is a progressive disorder in which patients are characterized by severe central nervous system degeneration together with mild somatic disease. III results from deficiency one of the four enzymes involved degradation heparan sulfate, sulfamidase (SGSH) being deficient IIIA and a-N-acetylglucosaminidase (NAGLU) IIIB. Mutation screening using SSCP/heteroduplex analysis on genomic DNA fragments was performed five Turkish eight IIIB...
Vitamin A deficiency iS considered a widespread public health problem among preschool children In the developing countries. limited number of studies reveal an association between xerophthalmia and significant systemic diseases including protein-energy malnutrition, diarrhoea, acute respiratory infections. The present study was carried out to assess vitamin status who have history recurrent infections diarrhoea. We already shown that serum levels all groups were lower than control group...
Abstract. Özalp, I., Hasanoĝlu, A., Tunçbilek G. and Yalaz, K. (Institute of Child Health, Hacettepe University, Ankara, Turkey). Hyperlysinemia without clinical findings. Acta Paediatr Scand, 70: 951, 1981.‐A three‐year‐old asymptomatic boy with hyperlysinemia is presented. The patient's plasma lysine levels have been constantly high (685‐1 370 μmol/l) excessive urinary excretion ornithine, arginine cystine noted. There was no detectable activity lysine‐ketoglutarate reductase nor...