- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- Cervical and Thoracic Myelopathy
- Scoliosis diagnosis and treatment
- Anesthesia and Pain Management
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Spinal Hematomas and Complications
- Orthopaedic implants and arthroplasty
- Moyamoya disease diagnosis and treatment
- Shoulder Injury and Treatment
- Pain Management and Opioid Use
- Vitamin D Research Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Neurological Complications and Syndromes
- RNA modifications and cancer
- Neurogenetic and Muscular Disorders Research
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Oral and Maxillofacial Pathology
- Telomeres, Telomerase, and Senescence
- Nausea and vomiting management
- Bone health and osteoporosis research
- Amoebic Infections and Treatments
Chulalongkorn University
2015-2025
King Chulalongkorn Memorial Hospital
2015-2025
Thai Red Cross Society
2013-2024
Bangkok Hospital
2022
Orthopaedic Research
2016
Walter Reed Army Institute of Research
2003
Columbia Orthopaedic Group
2001-2002
University of Missouri
2002
Alfred I. duPont Hospital for Children
2000
Retrospective cohort study.This study aimed to report the incidence and potential risk factors of polyetheretherketone (PEEK) cage subsidence following oblique lateral interbody fusion (OLIF) for lumbar degenerative diseases. We proposed also an algorithm minimize OLIF surgery.The included a retrospective 107 consecutive patients (48 men 59 women; mean age, 67.4 years) who had received either single- or multi-level between 2012 2019. Patients were classified into non-subsidence groups. PEEK...
Study Design. A retrospective study (level of evidence: level 4). Objective. To evaluate the radiographic outcomes after extreme lateral lumbar interbody fusion (XLIF) and oblique (OLIF) procedures especially effect indirect decompression to ligamentum flavum facet degeneration these procedures. Summary Background Data. Indirect via provides spinal canal area expansion. However, thickness at operated is unclear. Methods. Thirty-five patients (57 levels) underwent XLIF or OLIF with...
This was a cadaver study assessing the accuracy of cervical pedicle screw placement.To evaluate funnel technique placement.Although excellent results have been reported in clinical studies, with no major neurovascular injuries, several cadaveric studies shown high perforation rate during placement.Ten fresh frozen spines (C2-C7) were used (120 pedicles, 20 pedicles per level). The average specimen age 79.6 years (range 65-97); height 159 cm 155-175). male-to-female ratio 3:7. Pedicle width...
Oblique lumbar interbody fusion (OLIF), performed using a retroperitoneal approach, can lead to complications related the such as sympathetic chain injury (LSCI). Although LSCI is common complication of OLIF, its reported incidence varies across studies due an absence specific diagnostic criteria. Moreover, research on risk factors postoperative injuries after OLIF remains limited. Therefore, this study aimed describe incidence, and identify independent for LSCI, in patients with...
A prospective analytic study. To investigate the clinical factors and magnetic resonance imaging (MRI) findings that can predict a favorable outcome following transforaminal epidural steroid injection (TFESI) in patients with lumbosacral radiculopathy. The efficacy of lumbar varies, no parameters have been established to response TFESI reliably. In total, 120 diagnosed radiculopathy underwent TFESI. At each index spinal level, 5.0 mg dexamethasone mixture 2.0% lidocaine 0.5% bupivacaine was...
Lumbar disc degeneration (LDD) is a common musculoskeletal disorder that leads to chronic pain and functional impairment. Recent studies have suggested the vitamin D receptor (VDR) plays key part in regulating matrix metabolism, inflammation, apoptosis intervertebral discs (IVDs). The objective of this study was examine cytokine expression DNA methylation status VDR gene blood leukocytes lumbar tissues from patients with varying degrees LDD severity. We aimed explore correlations between...
No consensus criteria have been established regarding ideal candidates for indirect decompression with lateral lumbar interbody fusion (LLIF), and contributing factors of failure were rarely reported. We aim to investigate the success rate by LLIF proposed selection identify risk associated failure, defined as persistent pain requiring revision direct decompression.Data from 191 patients undergoing retrospectively reviewed. All following must be fulfilled: (1) dynamic clinical symptoms (pain...
Retrospective cohort study.To compare clinical and radiographic outcomes among minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF), extreme lateral (XLIF), oblique (OLIF) techniques.To date, there are many reports comparing between MIS-TLIF XLIF, OLIF, or XLIF OLIF procedures. However, no previous studies all these three techniques.Data from patients who underwent (MI) surgery for degenerative diseases at L4-L5 level was analyzed. Thirty each MIS-TLIF, groups were recruited...
Forty-six patients (25 male and 21 female) with arthrogryposis multiplex congenita who were seen at the Alfred I. duPont Hospital for Children between years 1940 1997 evaluated to assess prevalence patterns of scoliosis long-term results after both nonsurgical surgical treatment methods. We found be 65.9% (32 46 patients). A single thoracolumbar curve was predominant pattern. No congenital types or vertebral anomalies in our group patients. In group, mean <30° follow-up. primary before...
Study Design: This was a randomized double-blind controlled study.Purpose: study designed to evaluate the effects of intravenous nefopam regarding its ability reduce morphine consumption and postoperative pain improve recovery in patients undergoing open spine surgery.Overview Literature: Multimodal analgesia, including nonopioid medications, is essential for management surgery. Evidence use surgery as part enhanced after lacking.Methods: In this study, 100 lumbar decompressive laminectomy...
Forty-six patients (25 male and 21 female) with arthrogryposis multiplex congenita who were seen at the Alfred I. duPont Hospital for Children between years 1940 1997 evaluated to assess prevalence patterns of scoliosis long-term results after both nonsurgical surgical treatment methods. We found be 65.9% (32 46 patients). A single thoracolumbar curve was predominant pattern. No congenital types or vertebral anomalies in our group patients. In group, mean <30 degrees follow-up. primary...
Randomized double-blind control study.To evaluate the effects of nefopam on reducing morphine consumption and postoperative pain in patients undergoing minimally invasive spine surgery (MISS) to its enhanced recovery after surgery.Enhanced (ERAS) has become a major goal for surgery. Multimodal management combining non-opioid analgesics is key element this. However, there little evidence regarding use as part an ERAS protocol.One hundred MISS were randomized into two groups. Patients group...
This study is a retrospective review of the clinical results patients treated with thoracic pedicle screws using "funnel technique." The objective to report funnel technique for screw placement. A total 115 use at least one were retrospectively identified. All single medical center, under senior author's supervision. Twenty-five different residents responsible placing 50-60% these screws, and five fellows author placed remainder. accuracy placement complications related analyzed by assessing...
A descriptive in vitro study on isolation and differentiation of human mesenchymal stem cells (MSCs) derived from the facet joints interspinous ligaments.To isolate ligaments investigate their surface marker profile potentials.Lumbar spinal canal stenosis ossification posterior longitudinal ligament are progressive conditions characterized by hypertrophy within canal. MSCs believed to play a role advancement these diseases existence has been demonstrated ligamentum flavum ligament. The aim...
Lumbar spinal stenosis (LSS) is a common cause of low back pain with degenerative change in older adults. Telomeres are repetitive nucleoprotein DNA sequences TTAGGG at the ends chromosomes. Oxidative stress originates from an imbalance pro-oxidant and antioxidant homeostasis that results production reactive oxygen species (ROS). The purpose this study was to investigate relative telomere length (RTL) oxidative damage ligamentum flavum (LF) tissue LSS patients.Forty-eight patients...