A5102016251- Enzyme Structure and Function
- Protein Structure and Dynamics
- Computational Drug Discovery Methods
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Birth, Development, and Health
- Plant biochemistry and biosynthesis
- Insurance, Mortality, Demography, Risk Management
- Psychological Well-being and Life Satisfaction
- Innovative Teaching and Learning Methods
- Nuclear Receptors and Signaling
- Protein Degradation and Inhibitors
- Exercise and Physiological Responses
- Online and Blended Learning
- Macrophage Migration Inhibitory Factor
- Sleep and Work-Related Fatigue
- Global Health Care Issues
- Sleep and related disorders
- Acute Myeloid Leukemia Research
- Inflammasome and immune disorders
- Problem and Project Based Learning
- PI3K/AKT/mTOR signaling in cancer
- Heat shock proteins research
Sir Run Run Shaw Hospital
2022
Zhejiang University
2013-2022
Hangzhou Academy of Agricultural Sciences
2013-2016
Understanding protein-protein interactions (PPIs) is quite important to elucidate crucial biological processes and even design compounds that interfere with PPIs pharmaceutical significance. Protein-protein docking can afford the atomic structural details of complexes, but accurate prediction three-dimensional structures for systems still notoriously difficult due in part lack an ideal scoring function docking. Compared most functions used docking, Molecular Mechanics/Generalized Born...
Abstract Objectives Along with the development of times and progress society, total fertility rate (TFR) markedly changed in each country. Therefore, it is critical to describe trend TFR explore its influencing factors. However, previous studies did not consider time lag cumulative effect associations between factors TFR. Thus, our study aimed analyze from a new dimension. Methods The was employed using national-level data World Bank United Nations Development Programme. Distributed...
Deciphering the structural determinants of protein-protein interactions (PPIs) is essential to gain a deep understanding many important biological functions in living cells. Computational approaches for modeling PPIs, such as docking, are quite needed complement existing experimental techniques. The reliability docking method dependent on ability scoring function accurately distinguish near-native binding structures from huge number decoys. In this study, we developed HawkRank, novel...
Acute myeloid leukemia (AML) is a heterogeneous disorder with aberrant regulation of variety signal pathways. Therefore, simultaneous targeting two or even more deregulated transduction pathways needed to overcome drug resistance. Previously, it was reported that SNS-032, selective cyclin-dependent kinase inhibitor, an effective agent for treatment AML; however, the molecular mechanisms SNS-032-induced cell death AML cells are not yet fully understood. The aim study characterize effects in...
Macrophage migration inhibitory factor (MIF) is a multi-functional protein that acts as cytokine and an enzyme.
Abstract Background Virtual manipulatives (VMs) are increasingly adopted in inquiry activities. However, the effects of ratio mobile device‐based VMs to students and external scripts (a guiding structure for prompting group process) provision on interaction has not been detailed. Objectives This study proposed four different technology affordance conditions collaborative learning: 1:1 device‐student (one tablet per student) with scripts, 1:m group) without scripts. The purpose this is...