A5064656762- Connective tissue disorders research
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Issues in Pregnancy
- Mechanical Circulatory Support Devices
- Cardiovascular Conditions and Treatments
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Cardiac Arrhythmias and Treatments
- Healthcare Policy and Management
- Cardiovascular Effects of Exercise
- Ultrasound in Clinical Applications
- Radiation Dose and Imaging
- Cardiac Structural Anomalies and Repair
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular and Diving-Related Complications
- Non-Invasive Vital Sign Monitoring
Karolinska Institutet
2020-2025
Karolinska University Hospital
2020-2024
Schneider Children's Medical Center
2023
Universität Hamburg
2012-2015
University Medical Center Hamburg-Eppendorf
2012-2015
Martini-Klinik
2015
University Cancer Center Hamburg
2013
Recurrent coarctation of the aorta (re-CoA) is a well-known although not fully understood complication after surgical repair, typically occurring in 10%-20% cases within months discharge. To (1) characterize geometry aortic arch and blood flow from pre-discharge magnetic resonance imaging (MRI) neonates CoA repair; (2) compare these measures between patients that developed re-CoA 12 repair who did not. Neonates needing without associated major congenital heart defects, were included....
Cardiovascular pathology, including aortic root dilation at the level of sinus Valsalva (SV), is one major causes morbidity in paediatric patients with Marfan syndrome (MFS). β-Blocker (BB) well established to slow MFS. Less known about effectiveness angiotensin II receptor blocker (ARB) on MFS.215 MFS (9.01 ± 5.7 years) were subject a standardised diagnostic programme. Aortic was evaluated and followed up by echocardiography. In 48 cases, BB ARB effects evaluated. Effect treatment measured...
Abstract Aim Due to age‐dependent manifestations, diagnosis of M arfan syndrome ( MFS ) in children and adolescents is sophisticated. Although revised Ghent criteria a major step forward, its utility still restricted due expensive technically advanced diagnostics. As early submits long‐term benefits concerning prognosis, the need an appropriate diagnostic tool for risk stratification suspected paediatric patients with justified. Methods results Sixty were subject standardized programme. All...
Marfan syndrome (MFS) is a progressive, life-threatening genetic disorder of the connective tissue, which causes impaired quality life (QoL) in adults. This study investigated children and adolescents, taking into account their gender, age how MFS affected organs.This prospective nonrandomised single-centre included 46 patients with verified mean 10.98 years (±3.72). QoL was measured using self-reported, multidimensional KINDL-R questionnaire compared an age-matched control group 174...
BACKGROUND: Mixed venous oxygen saturation (SvO 2 ) is a critical variable in the assessment of supply and demand but rarely used children due to invasive nature pulmonary artery catheters. The aim this prospective, observational study was investigate accuracy noninvasively measured SvO acquired by novel capnodynamic method, based on differential Fick equation (Capno-SvO ), against gold standard CO-oximetry. METHODS: Capno-SvO compared blood gas CO-oximetry undergoing cardiac catheter...
Periprocedural and postinterventional care of patients undergoing closure patent foramen ovale (PFO) varies significantly across providers. Same-day discharge (SDD) after transcatheter interventions is an evolving concept. This study aimed to assess the same-day rate incidence complications in PFO with intracardiac echocardiography (ICE) using Gore®Cardioform Septal Occluder (GSO) device. The secondary aim was analyse efficacy femoral vein Perclose ProGlide.
Purpose Evaluate Piccolo and ADOII devices for transcatheter patent ductus arteriosus (PDA) closure. has smaller retention discs reducing risk of flow disturbance but residual leak embolization may increase. Methods Retrospective review all patients undergoing PDA closure with an Amplatzer device between January 2008 April 2022 in our institution. Data from the procedure 6 months follow-up were collected. Results 762 patients, median age 2.6 years (range 0–46.7) weight 13 kg 3.5–92) referred...
To estimate risk for exposure-induced cancer death (REID), organ-specific risks of (REID
Due to age dependent organ manifestation, diagnosis of Marfan syndrome (MFS) is a challenge, especially in childhood. It important identify children at risk MFS as soon possible direct those appropriate treatment but also avoid stigmatization due false diagnosis. We published the Kid-Short Score (Kid-SMS) 2012 stratify pre-test probability Hence we now evaluate predictive performance Kid-SMS new cohort children. prospectively investigated 106 patients who were suspected having MFS. At...
Abstract Aim To describe our initial experience with the indications and results of 5/7 Occlutech® duct Occluder (ODO, Occlutech International AB, Helsingborg, Sweden). A small incremental increase in occluder sizes is utmost importance for successful outcomes, especially smaller patients whom protrusion distal disk towards aorta should be minimised. Methods Retrospective study all undergoing PDA closure ODO three institutions since 2018. Results The was used 18 median age weight at time...
Background: Marfan syndrome (MFS) is an inherited connective-tissue disorder classically caused by different mutations in FBN1 gene. In childhood specific type of mutation and its correlation with cardiac pathologies deficient known. This study evaluates detailed association pathology. After all we want to evaluate whether there a need differentiate between concerning prognosis, follow-up medical treatment.
Background: Cardiovascular pathology, including aortic root dilation at the level of sinus Valsalva (SV), is one major causes morbidity in pediatric patients with Marfan syndrome (MFS). Beta Blockade (BB) well established to slow down MFS. Less known about effectiveness angiotensin receptor blocker (ARB) on
Background: Marfan syndrome (MFS) is an inherited connective-tissue disorder, caused by a mutation in the FBN1 gene. Diagnosis of MFS relies on revised Ghent criteria (RGC) with three cardinal clinical symptoms: dilatation sinus Valsalva (SV), ectopia lentis (EL), and systemic manifestation (Sys). We analyzed prevalence age symptoms according to RGC patients without FBN1. Finally, we also wanted evaluate whether it suggestive distinguish or concerning regular follow-up prophylaxis.