Abstract Background Knowledge about age-specific normal values for left ventricular mass (LVM), end-diastolic volume (EDV), end-systolic (ESV), stroke (SV) and ejection fraction (EF) by cardiac magnetic resonance imaging (CMR) is of importance to differentiate between health disease assess the severity disease. The aims study were determine age gender specific reference explore physiological variation these parameters from adolescence late adulthood, in a cross sectional study. Methods...

Background— The time course and magnitude of infarct involution, functional recovery, normalization infarct-related electrocardiographic (ECG) changes after acute myocardial infarction (MI) are not completely known in humans. We sought to explore these processes early MI during infarct-healing using cardiac MRI. Methods Results— Twenty-two patients with reperfused first-time were examined by MRI ECG at 1, 7, 42, 182, 365 days infarction. Global left ventricular function regional wall...

The time course of infarct evolution, i.e. how fast myocardial infarction (MI) develops during coronary artery occlusion, is well known for several species, whereas no direct evidence exists on the evolution MI size normalized to myocardium at risk (MaR) in man. Despite lack evidence, current literature often refers "golden hour" as which salvage can be accomplished by reperfusion therapy. Therefore, aim present study was investigate duration ischemia affects man relation previous animal...

Fetal cardiovascular magnetic resonance (CMR) imaging may provide a valuable adjunct to fetal echocardiography in the evaluation of congenital pathologies. However, dynamic CMR is difficult due lack direct in-utero cardiac gating. The aim this study was investigate effectiveness newly developed Doppler ultrasound (DUS) device humans for Fifteen fetuses (gestational age 30–39 weeks) were examined using 1.5 T scanners at three different sites. A CMR-compatible DUS used generate gating signals...

<h3>Importance</h3> Prenatal diagnosis of complex congenital heart defects reduces mortality and morbidity in affected infants. However, fetal echocardiography can be limited by poor acoustic windows, there is a need for improved diagnostic methods. <h3>Objective</h3> To assess the clinical utility cardiovascular magnetic resonance imaging cases which could not visualize all relevant anatomy. <h3>Design, Setting, Participants</h3> This cohort study was conducted between January 20, 2017,...

Abstract Background Photon-counting computed tomography (PCCT) is a new clinical method that may show better diagnostic quality at lower radiation doses than conventional CT. Objective To investigate the and dose of paediatric cardiovascular PCCT for diagnosis congenital heart defects 70 kV 90 kV. Materials methods This retrospective assessment included non-gated examinations defects. Radiation were recorded, overall specific (1–4) scored by four radiologists. Agreement, differences, trends...

Purpose To develop and assess a technique for self-gated fetal cardiac cine magnetic resonance imaging (MRI) using tiny golden angle radial sampling combined with iGRASP (iterative Golden-angle RAdial Sparse Parallel) accelerated acquisition based on parallel compressed sensing. Materials Methods Fetal data were acquired from five volunteers in gestational week 29–37 at 1.5T angles eddy currents reduction. The multicoil projections input to principal component analysis-based compression...

The geometrical relationship between atrial and ventricular short-axis cross-sectional area determines the hydraulic forces acting on intracardiac blood. This is important for diastolic filling. In patients undergoing heart transplantation (HTx), left atrium often enlarged as a result of standard surgical technique. We hypothesized that filling in HTx affected by surgery altering ventricle.

Objective. Accurate and reproducible assessment of myocardial infarction is important for treatment planning in patients with ischemic heart disease. This study describes a novel method to quantify by semi-automatic delineation hyperenhanced myocardium delayed contrast enhanced (DE) magnetic resonance (MR) images. Design. The proposed automatically detects the tissue first determining signal intensity non-enhanced myocardium. A fast level set algorithm was used limit heterogeneity regions,...

The effects of negative pressure wound therapy (NPWT) on edge microvascular blood flow are not clear. aim the present study was therefore to further elucidate NPWT periwound in a porcine peripheral model using different measurement techniques. at -20, -40, -80, and -125 mmHg applied (n = 8). Thermodiffusion, transcutaneous, invasive laser Doppler velocimetry were used measure perfusion 0.5, 1.0, 2.5 cm from edge. Thermodiffusion (an technique) generally showed decrease close (0.5 cm), an...

Introduction. Manual delineation of the left ventricle is clinical standard for quantification cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account one major contributor to stroke volume, long-axis motion. Therefore, aim this study was develop validate an algorithm time-resolved segmentation covering whole ventricle, including basal slices affected by Methods. Ninety subjects imaged with a cine...

Background Fetal cardiovascular MRI complements ultrasound to assess fetal pathophysiology. Purpose To develop a free‐breathing method for retrospective cine using Doppler (DUS) cardiac gating and tiny golden angle radial sampling (tyGRASP) accelerated acquisition capable of detecting movements motion compensation. Study Type Feasibility study. Subjects Nine volunteers (gestational week 34–40). Short‐axis four‐chamber views were acquired during maternal breath‐hold. Field Strength/Sequence...

In the situation of acute coronary occlusion, myocardium supplied by occluded vessel is subject to ischemia and referred as at risk (MaR). Single photon emission computed tomography has previously been used for quantitative assessment MaR. It is, however, associated with considerable logistic challenges employment in clinical routine. Recently, T2-weighted cardiovascular magnetic resonance (CMR) introduced a new method assessing MaR several days after event. Furthermore, it suggested that...

Pulse wave velocity (PWV) is a biomarker for arterial stiffness, clinically assessed by applanation tonometry (AT). Increased use of phase-contrast cardiac magnetic resonance (CMR) imaging allows PWV assessment with minor routine protocol additions. The aims were to investigate the acquired temporal resolution needed accurate and precise measurements CMR-PWV, develop tool CMR-PWV measurements.Computer phantoms generated = 2-20 m/s based on human data. performed in 13 healthy young subjects...

Intracardiac hemodynamic forces have been proposed to influence remodeling and be a marker of ventricular dysfunction. We aimed quantify the in patients with repaired tetralogy Fallot (rToF) further understand pathophysiological mechanisms as this could potential for pulmonary valve replacement (PVR) these patients. Patients rToF regurgitation (PR) &gt; 20% ( n = 18) healthy control subjects 15) underwent MRI, including four-dimensional flow. A subset 8) PVR MRI after surgery. Time-resolved...

Negative pressure wound therapy (NPWT) contracts the and alters in tissue of edge, which accelerates healing. The aim this study was to examine effect type (foam or gauze) size (small large) filler for NPWT on contraction pressure. pressures between --20 --160 mmHg were applied a peripheral porcine (n = 8). edge measured at distances 0·1, 0·5, 1·0 2·0 cm from diameter determined. At 0·1 decreased when applied, whereas 0·5 it increased. Tissue not affected edge. pressure, greater using small...

Introduction. Manual delineation of the left ventricle is clinical standard for quantification cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account one major contributor to stroke volume, long-axis motion. Therefore, aim this study was develop validate an algorithm time-resolved segmentation covering whole ventricle, including basal slices affected by Methods. Ninety subjects imaged with a cine...

A bstract After a discussion of the underlying principles, some electromagnetic model experiments made primarily in connection with development ABEM airborne method are described. The were on thin vertical and horizontal conductors “infinite” extent coil arrangements involving one transmitter receiver unit. in‐phase out‐of‐phase components field picked up by measured percent amplitude normal at receiver. In this case 1° phase‐shift corresponds to 1.75 % amplitude. scale 600–2000 times...

Fetal cardiovascular magnetic resonance (CMR) imaging is used clinically and for research, but has been previously limited due to lack of direct gating methods. A CMR-compatible Doppler ultrasound (DUS) device resolved this. However, the DUS-gating method not validated against current reference fetal phase-contrast blood flow measurements, metric optimized (MOG). Further, we investigated how different methods vessel delineation affect volumes observer variability in acquisitions.

Background Fetal cardiac magnetic resonance imaging (MRI) improves the diagnosis of congenital heart defects, but is sensitive to fetal motion due long image acquisition time. This may be overcome with faster low resolution, followed by enhancement provide clinically useful images. Purpose To combine phase‐encoding undersampling super‐resolution neural networks achieve high‐resolution cine MR images short Study Type Prospective. Subjects Twenty‐eight fetuses (gestational week 36...

Recurrent coarctation of the aorta (re-CoA) is a well-known although not fully understood complication after surgical repair, typically occurring in 10%-20% cases within months discharge. To (1) characterize geometry aortic arch and blood flow from pre-discharge magnetic resonance imaging (MRI) neonates CoA repair; (2) compare these measures between patients that developed re-CoA 12 repair who did not. Neonates needing without associated major congenital heart defects, were included....