A5042198067- Advanced MRI Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Hemoglobinopathies and Related Disorders
- MRI in cancer diagnosis
- Iron Metabolism and Disorders
- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Radiation Dose and Imaging
- Liver Diseases and Immunity
- Neonatal and fetal brain pathology
- Appendicitis Diagnosis and Management
- Advanced Neuroimaging Techniques and Applications
- Gallbladder and Bile Duct Disorders
- Radiomics and Machine Learning in Medical Imaging
- Diversity and Career in Medicine
- Ultrasound and Hyperthermia Applications
- Diverticular Disease and Complications
- Nutrition and Health in Aging
- Trace Elements in Health
- Medical Imaging Techniques and Applications
- Sarcoma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
Universität Hamburg
2015-2024
University Medical Center Hamburg-Eppendorf
2015-2024
Klinik und Poliklinik für Nuklearmedizin
2018-2023
Advanced Imaging Research (United States)
2023
The University of Texas Southwestern Medical Center
2023
Eppendorf (Belgium)
2021
University Hospital and Clinics
2010
University Medical Center
2010
Klinik und Poliklinik für Neurologie
2006-2009
Eppendorf (Germany)
2007-2008
Purpose To explore the use and reproducibility of magnetic resonance‐derived myocardial T 1 mapping in patients with iron overload. Materials Methods The research received ethics committee approval all provided written informed consent. This was a prospective study 88 67 healthy volunteers. Thirty‐five underwent repeat scanning for reproducibility. used shortened modified Look–Locker inversion recovery sequence (ShMOLLI) second, confirmatory MOLLI group. 2 * performed using commercially...
Fetal cardiovascular magnetic resonance (CMR) imaging may provide a valuable adjunct to fetal echocardiography in the evaluation of congenital pathologies. However, dynamic CMR is difficult due lack direct in-utero cardiac gating. The aim this study was investigate effectiveness newly developed Doppler ultrasound (DUS) device humans for Fifteen fetuses (gestational age 30–39 weeks) were examined using 1.5 T scanners at three different sites. A CMR-compatible DUS used generate gating signals...
Purpose We aimed to determine the agreement between quantitative susceptibility mapping (QSM)‐based biomagnetic liver susceptometry (BLS) and confounder‐corrected R2* with superconducting quantum interference device (SQUID)‐based in patients iron overload. Methods Data were acquired from two healthy controls 22 undergoing MRI SQUID‐BLS as part of routine monitoring for Magnetic resonance imaging was performed on a 3T system using three‐dimensional multi‐echo gradient‐echo acquisition. Both...
Abstract As most COVID-19 patients only receive thoracic CT scans, but body composition, which is relevant to detect sarcopenia, determined in abdominal this study aimed investigate the relationship between and composition parameters a cohort of patients. This retrospective included n = 46 SARS-CoV-2-positive who received scans thorax abdomen due severe disease progression. The subcutaneous fat area (SF), skeletal muscle (SMA), radiodensity attenuation (MRA) were measured at level twelfth...
Objectives Fat quantification by dual-energy computed tomography (DECT) provides contrast-independent objective results, for example, on hepatic steatosis or muscle quality as parameters of prognostic relevance. To date, fat has only been developed and used source-based DECT techniques fast kVp-switching CT dual-source CT, which require a prospective selection the imaging mode. It was purpose this study to develop material decomposition algorithm in phantoms validate it vivo patient liver...
Summary Background In patients with primary sclerosing cholangitis follow‐up magnetic resonance imaging (MRI) cholangiopancreatography (MRCP) is performed by many centres, particularly for the early detection of biliary malignancies and strictures. Clinically meaningful MRI ‐based definitions related complications are, however, lacking. Aim To investigate how experts interpret MRI/MRCP a focus on conclusions that may impact clinical decision‐making in cholangitis. Methods Within...
To quantify the proportion of fat within skeletal muscle as a measure quality using dual-energy CT (DECT) and to validate this methodology with MRI.Twenty-one patients abdominal contrast-enhanced DECT scans (100 kV/Sn 150 kV) underwent 3-T MRI. The fraction (DECT-FF), determined by material decomposition, HU values on virtual non-contrast-enhanced (VNC) images were measured in 126 regions interest (≥ 6 cm2) posterior paraspinal muscle. For validation, MR-based (MR-FF) was assessed chemical...
Abstract Objectives To evaluate work expectations of radiologists at different career levels, their fulfillment, prevalence exhaustion, and exhaustion-associated factors. Methods A standardized digital questionnaire was distributed internationally to all levels in the hospital ambulatory care via radiological societies sent manually 4500 largest German hospitals between December 2020 April 2021. Statistics were based on age- gender-adjusted regression analyses respondents working Germany...
Purpose Accurate triggering of the cardiac cycle is mandatory for optimal image acquisition and thus diagnostic quality in magnetic resonance imaging. The purpose this work was to evaluate Doppler ultrasound as an alternative trigger method MRI. Methods Steady‐state free precession (SSFP) 2D cine CMR performed 11 healthy subjects at 1.5T. (DUS), electrocardiogram (ECG) pulse oximetry (POX) were used triggering. DUS peak detection verified comparison ECG. Quantitative analysis each gating...
To investigate the diagnostic performance of dynamic fetal cardiac magnetic resonance imaging (MRI), using a MR-compatible Doppler ultrasound (DUS) device for gating, in differentiating fetuses with congenital heart disease from those normal heart, and to compare technique echocardiography.This was prospective study eight four (CHD), at median 34 (range, 28-36) weeks' gestation. Dynamic MRI performed DUS direct gating. The four-chamber view evaluated according qualitative findings....
To determine the pancreatic iron (R2*) and fat content (FC) in comparison to hepatic cardiac R2* patients with overload disorders like β-thalassemia major (TM), Diamond-Blackfan anemia (DBA) or hereditary hemochromatosis.R2* rates were assessed liver, heart pancreas of 42 TM, 29 subjects other diseases, 10 controls using an ECG-gated breathhold sequence (12 echo time [TE] = 1.3-25.7 ms, readout repetition [TR] 244 ms). Pancreatic FC from TE dependent region interest based signal intensities...
Abstract Background Obesity has been shown to trigger adaptive increases in pancreas parenchymal and fat volume. Consecutively, pancreatic steatosis may lead beta‐cell dysfunction. However, it is not known whether the tissue components decrease with weight loss reversible following Roux‐en‐Y gastric bypass (RYGB). Therefore, objective of study was investigate effects RYGB‐induced on volume glucose homeostasis. Methods Eleven patients were recruited Centre University Medical...
Fetal cardiac MRI has the potential to play an important role in assessment of fetal pathologies, but it is up now not feasible due a missing gating method. The purpose this work was evaluation Doppler ultrasound (DUS) for external with regard compatibility, functionality, and reliability. Preliminary results were assessed performing MRI.An conditional DUS device developed obtain signal from heart. compatibility evaluated at 1.5T 3T using B1 field maps gradient echo images. quality...
Purpose: To retrospectively evaluate the impact of diffusion-weighted imaging (DWI) on detection prostate cancer in comparison with sextant biopsy. Materials and Methods: Fifty patients clinical suspicion underwent a combined endorectal-body-phased array magnetic resonance examination at 1.5 T (Siemens, Erlangen, Germany). The DWI was performed using b values 50, 400, 800 s/mm2. divided into sextants, including apex, middle aspect, base for left right sides, separately. Regions interest were...
To investigate MRI of the fetal heart by way a novel triggering method with use an MR-compatible cardiotocography (CTG) in animal model.Fetal cardiac was performed on four pregnant ewes 1.5 Tesla (T) MR system. A CTG rendered compatible and its signal used for to perform cine maternal free-breathing steady-state free precession. The left ventricular volume function were measured from short-axis (view). image quality anatomical structures assessed.All valves foramen ovale could be visualized....