A5061174461- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Musculoskeletal pain and rehabilitation
- Pain Management and Treatment
- Pancreatitis Pathology and Treatment
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Medical Device Sterilization and Disinfection
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Surgical Treatments
- Spine and Intervertebral Disc Pathology
- Oral and Maxillofacial Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Pain Mechanisms and Treatments
- Tracheal and airway disorders
- Amoebic Infections and Treatments
- Gastrointestinal disorders and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Pain Management
- Foreign Body Medical Cases
- Salivary Gland Tumors Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Lymphoma Diagnosis and Treatment
University of Pittsburgh Medical Center
2024-2025
St. Elizabeth's Medical Center
2023-2025
Boston University
2024
Tufts Medical Center
2024
The Ohio State University Wexner Medical Center
2023
Hadassah Medical Center
2022
Lahey Hospital and Medical Center
2015-2022
Beth Israel Deaconess Medical Center
2022
Harvard University
2018-2022
Nottingham University Hospitals NHS Trust
2021
Cancer cachexia is a debilitating condition characterized by combination of anorexia, muscle wasting, weight loss, and malnutrition. This affects an overwhelming majority patients with pancreatic cancer primary cause cancer-related death. However, few, if any, effective therapies exist for both treatment prevention this syndrome. In order to develop novel therapeutic strategies cachexia, appropriate animal models are necessary. study, we developed validated syngeneic, metastatic, murine...
Chronic pain continues to be one of the leading healthcare cost burdens in United States and is typically defined as ongoing pain, lasting longer than six months. Various treatment options exist for chronic including physical therapy, medical management, psychology, interventional therapies. Pain medications have been mainstay conditions with an increasing use membrane stabilizers antidepressants treat neuropathic conditions. Specifically, serotonin noradrenaline reuptake inhibitors (SNRIs)...
A 27-year-old woman presented to her primary care doctor's office with left flank pain. CT of the abdomen showed an isolated renal vein thrombus. The clot was initially attributed oral contraceptive use; however, closer inspection images revealed nutcracker phenomenon (compression between superior mesenteric artery and abdominal aorta). Intravascular ultrasound imaging confirmed diagnosis. Nutcracker syndrome is a rare condition, which if untreated may cause damage kidney. Although under...
Headaches are among the most prevalent medical complaints globally. Occipital neuralgia is a chronic headache disorder characterized by unilateral or bilateral severe pain originating in neck skull base and radiating up along occipital nerve distribution. Effective treatment options for can be challenging some patients may prove to refractory conventional interventional therapies. We present case report on patient with that was refectory therapies responded percutaneous peripheral stimulation.
Submucosal tumors (SMTs) are often discovered incidentally during endoscopy as protrusions in the gastrointestinal wall, typically with intact overlying mucosa. While most SMTs arising from esophagus benign, some carry a risk of malignant transformation, warranting removal. Endoscopic resection provides minimally invasive option that preserves esophageal structure and function. This review outlines endoluminal techniques for located gastroesophageal junction. These include Mucosal Resection...
Postherpetic neuralgia (PHN) is one of the most debilitating forms neuropathic pain that can occur after a herpes zoster infection. PHN significantly impair patients’ quality life due to persistent pain. Current first-line treatments for include anticonvulsants like gabapentin and pregabalin, topical agents such as lidocaine patches, opioids in severe cases. However, many patients fail achieve adequate control with these medications. Tricyclic antidepressants (TCAs) amitriptyline...
Regulation of Toll-like receptor responses is critical for limiting tissue injury and autoimmunity in both sepsis sterile inflammation. We found that Mincle, a C-type lectin receptor, regulates proinflammatory 4 signaling. Specifically, Mincle ligation diminishes 4-mediated inflammation, whereas deletion or knockdown results marked hyperresponsiveness to lipopolysaccharide vitro, as well overwhelming lipopolysaccharide-mediated inflammation vivo. Mechanistically, does not up-regulate...
Facet joint injections with steroids are a common therapeutic intervention for chronic pain management, particularly in patients lumbar spondylosis and facet arthropathy. However, many insurance companies do not provide coverage this helpful intervention. This case series presents four who experienced significant sustained relief following injections. The aim of is to highlight the efficacy managing spinal discuss potential benefits treatment modality may be interested pursuing...
Malignant esophageal strictures often require stent placement to alleviate dysphagia and improve quality of life. We present a novel application lumen-apposing metal bypass malignant stricture in the setting altered gastric anatomy.
The patient, who underwent laparoscopic cholecystectomy 3 months ago, now has abdominal pain and a spot on computed tomography that could be liver abscess. But is it?
The introduction of lumen-apposing metal stents (LAMS) has been an important development in the management pancreatic fluid collections. Stent migration out collections into stomach reported, despite special anti-migratory design bi-flanged stent. Data on stent rates remain sparse, with some studies suggesting a rate 3.3-5%. There have no reported cases LAMS outside stomach. We describe first case transgastric migrating from and passing colon.
Breast lymphoma is an uncommon neoplasm affecting the breast and extremely rare in males. While gynaecomastia common most cases benign, it can sometimes result from significant pathology physician should keep mind possible diseases that lead to gynaecomastia. This paper reports a case of presenting as unilateral The discusses differential diagnosis emphasises points raise suspicion pathology.Mammography, high resolution ultrasound biopsy findings are discussed literature survey presented.
Walled-off pancreatic necrosis (WOPN) is one of the late complications acute pancreatitis. We present a 37-year-old man who developed large WOPN 6 weeks after treatment severe complicated Imaging studies revealed necrotic retroperitoneal fluid collection measuring 27 × 12 cm with crossing blood vessels. Cystogastrostomy was performed using lumen-apposing metal stent. He underwent multiple necrosectomies significant improvement in cyst size. Bleeding major complication direct endoscopic...
Bile duct adenomas (BDAs) are rare benign tumors that can arise in the intra-hepatic or extra-hepatic biliary tree. We present a case of 46-year-old female who presented with symptoms suggestive choledocholithiasis. Direct cholangioscopy identified 15 mm polypoid lesion common hepatic (CHD). Biopsy revealed BDA. this to highlight role direct diagnosis and management BDAs.
ABSTRACT Primary gastric diffuse large B-cell lymphoma (PG-DLBCL) is a rare malignant neoplasm. While the association between Heliobacter pylori infection and mucosa-assisted lymphoid tissue well established, data supporting its with DLBCL are less robust. Here we present case of PG-DLBCL diagnosed H. . An 82-year-old man presented to clinic complaints worsening epigastric pain. He underwent an endoscopy which revealed 1 nonbleeding ulcer. Histopathological immunohistochemical analysis...