- Phytochemistry and Bioactive Compounds
- Medicinal Plants and Bioactive Compounds
- Diet, Metabolism, and Disease
- Pharmacological Effects of Natural Compounds
- Natural Antidiabetic Agents Studies
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Pharmacogenetics and Drug Metabolism
- Apelin-related biomedical research
- Glutathione Transferases and Polymorphisms
- Food Industry and Aquatic Biology
- Phytochemicals and Antioxidant Activities
- Oral microbiology and periodontitis research
- Phytochemistry and Bioactivity Studies
- Fungal Biology and Applications
- Bacterial biofilms and quorum sensing
- Estrogen and related hormone effects
- Biosensors and Analytical Detection
- Drug-Induced Hepatotoxicity and Protection
- Alcohol Consumption and Health Effects
- Phytochemistry and Biological Activities
- Biochemical Acid Research Studies
Sri Krishnadevaraya University
2016-2023
The current study was designed to evaluate the renoprotective effect of hydro-alcoholic extract Caralluma fimbriata (CFE) against high-fat diet-induced oxidative stress in Wistar rats. Male rats were randomly divided into five groups: control (C), treated with CFE (C + CFE), diet fed (HFD), (HFD and metformin metformin). orally administered (200 mg/kg body weight) Groups C HFD for 90 days. Renal functional markers such as, urea, uric acid, creatinine levels plasma quantified during...
Diabetes mellitus has been associated with oxidative stress. The present study was performed to investigate the pancreas protective activities of Phyllanthus amarus aqueous extract (PAAEt) in streptozotocin (STZ) induced diabetic rats. Oral administration PAAEt (200mg/kg bw) rats for 60 days significantly (p<0.05) decreased antioxidant enzymes such as glutathione peroxidase, glutathione-s-transferase, reductase, superoxide dismutase, catalase and depletion reduced panceas which...
To investigate whether hydro-alcoholic extract of aerial parts Caralluma fimbriata (CFE) could attenuate high-fat diet (HFD) induced cardiac damage.Forty rats were divided into five groups: control (C), treated with CFE, HFD, HFD and metformin (Met).CFE treatment significantly (p < .001) attenuated HFD-induced increase in lipids such as total lipids, triglycerides, cholesterol, free fatty acids decreased phospholipids accompanied by increasing lipid peroxidation protein oxidation....
The present study investigated the effects of Salacia reticulata and simvastatin on oxidative stress insulin resistance in Sprague-Dawley (SD) rats. We compared protective effect a methanolic extract (SR) with (SVS) rats fed high-fat diet (HFD).Male were divided into following five different groups: control (C), C+SR, HFD, HFD+SR, HFD+SVS. High-fat showed hyperglycemia, hyperinsulinemia, hyperleptinemia, dyslipidemia, hypoadiponectinemia after 90 days. Treatment SR/SVS significantly (p <...
The present investigation planned to study the cardiovascular worries in Rose Bengal (RB) induced thrombotic rats by analysing biochemical profile of plasma, platelet membrane and cardiac tissue. Male Wistar were categorized into two groups. group I was Control (C) received glucose, whereas II (50 mg/kg) rats. animals sacrificed biological samples collected analysed for various parameters. In RB heart damage/thrombosis showed significantly increased levels lipid peroxidation (LPO), nitrate...
The investigating of study was expected to the lipid composition diabetes and alcoholic in plasma erythrocyte membrane biochemical profile rats. Diabetic male Wistar Streptozotocin (STZ)-induced rats were used experimental models. Control (C) maintained group I, received glucose (i.e., caloric equivalent), diabetic induced (STZ) II, III treated IV which 20 % (v/v) alcohol water, administered through stomach tube (5 g/kg body weight/day). STZ-induced hepatic damage observed leads increased...