- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Facial Trauma and Fracture Management
- Periodontal Regeneration and Treatments
- Facial Rejuvenation and Surgery Techniques
- Corneal surgery and disorders
- Hemostasis and retained surgical items
- Eicosanoids and Hypertension Pharmacology
- Advanced Glycation End Products research
- Proteoglycans and glycosaminoglycans research
- Glaucoma and retinal disorders
- Dermatologic Treatments and Research
- Intraocular Surgery and Lenses
- Retinopathy of Prematurity Studies
- Coronary Artery Anomalies
- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Traumatic Ocular and Foreign Body Injuries
- Platelet Disorders and Treatments
Helmholtz Moscow Research Institute of Eye Diseases
2019-2024
Primary open-angle glaucoma (POAG) is characterized by degeneration of retinal ganglion cells associated with an increase in intraocular pressure (IOP) due to hindered aqueous humor (AH) drainage through the trabecular meshwork and uveoscleral pathway. Polyunsaturated fatty acids oxylipins are signaling lipids regulating neuroinflammation, neuronal survival AH outflow. Among them, prostaglandins have been previously implicated employed for its treatment. This study addressed role determining...
This article is dedicated to the realistic, present-day problem in treating patients with a damaged cornea. It contains general summary of practical experience treatments various spheres medicine and ophthalmology particular, concerning new developing method restoring tissue aid platelet rich plasma. branch regenerative medicine. In an effective has long been sought for well-known that plasma high quantity elements which contribute growth: thrombocyte, transformation, insulin-like, epidermal...
Purpose : to evaluate the effectiveness of platelet-rich plasma (PRP) lysate in patients with corneal erosion or posttraumatic scarring eyelid tissues. Material and methods . The study involved 30 aged 22 82 (51.5 ± 19.1 years): 10 persistent erosions, who were treated 2 stages (2 weeks standard keratoprotective therapy, then treatment supplemented instillations PRP lysate) 20 post-traumatic tissues, divided into a clinical group comparison group. was produced cell transplantation...
The purpose . Using clinical observation, to study the feasibility of applying a coagulant and assess its efficacy in treatment patients with post-burn erosion cornea. Material methods was carried out Department Trauma Reconstructive Surgery, Helmholtz Moscow Research Institute Eye Diseases, Russia. Based on test results, patient, diagnosed persistent cornea sub-total conjunctivization and: limbal stem cell deficiency (LSCD) right eye. keratoprotective therapy conducted for several months...
Gelatinous drop-like corneal dystrophy (GDLD) is a rare autosomal recessive eye disease. GDLD characterized by the loss of barrier function in epithelial cells (CECs) and amyloid deposition due to pathogenic variants TACSTD2 gene. Limbal stem cell transplantation (LSCT) has been suggested as an effective therapeutic alternative for patients with GDLD. However, despite LSCT, recurs some patients. The pathogenesis recurrence poorly studied. We present case patient Genetic analysis revealed...
Purpose : to study the effectiveness of use thrombofibrin clot platelet-rich plasma (PRP) in patients with corneal ulcers. Material and methods . A clinical study, conducted by Department Traumatology Reconstructive Surgery Helmholtz National Medical Research Center Eye Diseases, involved 20 patients, aged from 22 82, ulcers inflammatory burn genesis more than 100 microns deep. All got coated a PRP autologous blood. Prior all received standard treatment for 2 weeks 3 months, including...
In addition to the classic Coats' disease characterized by retinal vascular telangiectasias and aneurysmal dilatations surrounded yellowish intra- subretinal exudates developing in somatically healthy children, Coats'-like changes can occur a number of systemic diseases complicate course other eye pathologies. One that with exudative vasculopathy is facioscapulohumeral muscular dystrophy, or Landouzy - Dejerine disease. Systemic manifestations this pathology are myodystrophic process, which...
Open eye injury (OTG), in the structure of damage is up to 35.0–85.0 %, level disability among working part male population from 26 55 years ranges 25.0–47.5 and removal eyeball due traumatic pathology 6.5–26.3 % cases. The aim work demonstrate consequences undiagnosed cases open injury, successfully treated Department traumatology reconstructive surgery. Attention focused on some diagnostic techniques that contribute correct diagnosis, especially unoperated timely sub — conjunctival sclera...
Purpose : to evaluate the effectiveness of platelet-rich plasma lysate (PRP) in treatment patients with post-traumatic eyelid scarring by clinical examples. Material and methods . Patients changes tissues causing a damage functional cosmetic state auxiliary apparatus eye were treated Department Plastic Surgery Eye Prosthetics at Helmholtz National Medical Research Center Diseases. Two patients, who had been traumatized shortly before examination one patient rejected surgery offered PRP...