A5007998832- Monoclonal and Polyclonal Antibodies Research
- Pain Mechanisms and Treatments
- Gastrointestinal motility and disorders
- Glycosylation and Glycoproteins Research
- Diabetes Treatment and Management
- Advanced Biosensing Techniques and Applications
- Pharmacology and Obesity Treatment
- Diet and metabolism studies
- Parkinson's Disease Mechanisms and Treatments
- Galectins and Cancer Biology
- Botulinum Toxin and Related Neurological Disorders
- Diabetes Management and Research
- Regulation of Appetite and Obesity
- Neurological disorders and treatments
- Advanced biosensing and bioanalysis techniques
- Cancer Cells and Metastasis
- Viral Infectious Diseases and Gene Expression in Insects
- Musculoskeletal pain and rehabilitation
- Diabetes and associated disorders
Aalborg University Hospital
2018-2021
Mech-Sense
2018-2021
Aalborg University
2018-2020
Creative Research Enterprises (United States)
2019
University of Copenhagen
2019
Innovation Fund Denmark
2019
Novo Nordisk (Denmark)
2019
Universiti Putra Malaysia
2019
Steno Diabetes Center North Jutland
2019
North Denmark Region
2019
One of the hallmarks cancer is an altered energy metabolism, and here, mitochondria play a central role. Previous studies have indicated that some mitochondrial ribosomal proteins change their expression patterns upon transformation. In this study, we used selection recombinant antibody libraries displayed on surface filamentous bacteriophage as proteomics discovery tool for identification breast biomarkers. A small subpopulation cells expressing both cytokeratin 19 14 was targeted using...
Abstract With the advent of modern technologies enabling single cell analysis, it has become clear that small sub‐populations cells or even can drive phenotypic appearance tissue, both diseased and normal. Nucleic acid based allowing analysis been faster to mature, while aimed at analysing proteome a level is still lacking behind, especially which allow in tissue. Introducing methods, allows such will pave way for discovering new biomarkers with more clinical relevance, as these may be...
Breast cancer tumors are composed of heterogeneous cell populations. These populations display a high variance in morphology, growth and metastatic propensity. They respond differently to therapeutic interventions, some may be more prone cause recurrence. Studying individual subpopulations breast provide crucial knowledge for the development individualized therapy. However, this process is challenged by availability biomarkers able identify specifically. Here, we demonstrate an approach...
We hypothesized that adults with type 1 diabetes and severe polyneuropathy have alterations in neuronal transmission at different anatomical levels. The aims were to investigate upstream sensory activation terms of peripheral, spinal, precortical, cortical transmission.48 participants type-1 polyneuropathy, 21 age-matched healthy included. Electrophysiological median nerve recordings used analyze peripheral Erb's point (P9-N11); spinal evoked potentials Cv7 (P11-N14); subcortical Oz...
Abstract Adipose tissue is the primary energy reservoir of human body, which also possesses endocrine functions. The glucagon‐like peptide agonist liraglutide produces weight loss, although specific effects on adipose are unknown. We aimed to characterize white composition and pericellular fibrosis subcutaneous in response treatment. Furthermore, we explored level circulating free fatty acids, cluster differentiation 163 (CD163) macrophage marker, leptin adiponectin. Thirty‐nine adults with...
is a peer-reviewed open access academic journal that aims to guide clinical practice and improve diagnostic therapeutic skills of clinicians.WJD covers topics concerning α, β, δ PP cells the pancreatic islet, effect insulin insulinresistance, islet transplantation, adipose obesity.
Gastrointestinal (GI) complications of diabetes mellitus are common and result in a significant diminution health-related quality life. Diabetes can affect almost every part GI tract from the oesophagus to rectum, causes variety symptoms including reflux, heartburn, nausea, vomiting, abdominal pain, diarrhoea constipation. Diabetes-induced collectively referred as diabetic enteropathy. Over recent years, investigation underlying pathogenesis diabetes-induced has provided objective evidence...
Comprehensive evaluation of the upstream sensory processing in diabetic symmetrical polyneuropathy (DSPN) is sparse. The authors investigated spinal nociceptive withdrawal reflex and related elicited somatosensory evoked cortical potentials. They hypothesized that DSPN induces alterations supraspinal sensory-motor compared with age- gender-matched healthy controls.In this study, 48 patients type 1 diabetes were 21 controls. Perception thresholds determined subjects received electrical...