A5061105178- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Ophthalmology and Eye Disorders
- Glaucoma and retinal disorders
- Schizophrenia research and treatment
- Cerebrovascular and Carotid Artery Diseases
- Balance, Gait, and Falls Prevention
- Psychosomatic Disorders and Their Treatments
- Hearing Impairment and Communication
- Vascular Malformations Diagnosis and Treatment
- Lower Extremity Biomechanics and Pathologies
- Cerebral Venous Sinus Thrombosis
- Ear Surgery and Otitis Media
- Obsessive-Compulsive Spectrum Disorders
- Hip disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Multiple Sclerosis Research Studies
- Orthopaedic implants and arthroplasty
- Mitochondrial Function and Pathology
- Genetic Neurodegenerative Diseases
- DNA Repair Mechanisms
- Multisensory perception and integration
University Hospital of Bern
2019-2025
University of Bern
2020-2025
Neurology, Inc
2022
Kantonsspital Aarau
2014-2020
Background and Purpose: The purpose of this study was to assess nationwide incidence outcomes aneurysmal subarachnoid hemorrhage (aSAH). Swiss SOS (Swiss Study on Subarachnoid Hemorrhage) established in 2008 offers the unique opportunity provide data from point care a level. Methods: All patients with confirmed admitted between January 1, 2009 December 31, 2014, within Switzerland were recorded prospective registry. Incidence rates calculated based time-matched population data. Admission...
Abstract Vestibular rehabilitation (VR) is practiced across Europe but little in this area has been quantified. The aim of study was to investigate current VR assessment, treatment, education, and research practices. This an online, cross-sectional survey with 39 specific questions four sections: demographics, practice, research. disseminated through the Dizzynet network individual therapists country-specific special interest groups. Results were analysed descriptively. A thematic approach...
<h3>Objective</h3> Failure of fixation suppression spontaneous nystagmus is sometimes seen in patients with vestibular strokes involving the cerebellum or brainstem; however, accuracy this test for discrimination between peripheral and central causes an acute syndrome (AVS) unknown. <h3>Methods</h3> Patients AVS were screened recruited (convenience sample) as part a prospective cross-sectional study emergency department 2015 2020. All received neuroimaging, which served reference standard....
Vertigo and dizziness are among the most frequent presenting symptoms in primary care physicians' (PCPs) office. With patients facing difficulties describing their complaints clinical findings often being subtle transient, diagnostic workup of dizzy patient remains challenging. We aimed to gain more insights into current state practice order identify limitations needs PCPs define strategies continuously improve knowledge patient.Board-certified working Switzerland were invited participate an...
Abstract Objectives Psychomotor slowing (PS) occurs in up to half of schizophrenia patients and is linked poorer outcomes. As standard treatment fails improve PS, novel approaches are needed. Here, we applied the RDoC framework using 3 units analysis, ie, behavior, self-report, physiology test, whether with PS different from without controls. Methods Motor behavior was compared between 71 25 42 healthy controls (HC) 5 measures: (1) for an expert rating scale: score Salpêtrière Retardation...
Schizophrenia is a severe mental disorder, in which 50% of the patients present with motor abnormalities such as psychomotor slowing. Slow spontaneous gait has been reported schizophrenia. However, comprehensive objective instrumental assessments multiple conditions are missing. Finally, specific patterns subjects slowing still unknown. Therefore, this study aimed to objectively assess parameters at different walking schizophrenia and without Also, we hypothesised impairments correlate...
Background The diagnostic workup and treatment decisions for vertigo or dizziness in primary care can be challenging due to the broad range of possible causes limited time expertise physicians. This lead delays unnecessary tests. We aimed identify unmet needs physicians (PCPs) strategies improve dizzy patients. Materials methods An online survey was conducted among board-certified PCPs Switzerland explore caring patients potential educational approaches. Results Based on responses from 152...
Vestibular symptoms are common in emergency department (ED) patients and have various causes, including stroke. Accurate identification of stroke with vestibular is crucial for timely management. We conducted a prospective cross-sectional study from 2015 to 2019 determine prevalence associated ED symptoms, aiming improve diagnosis outcomes.
Abstract Motor abnormalities, including psychomotor slowing, are prevalent in a large proportion of individuals with schizophrenia. While postural control deficits have been observed this population, the impact motor abnormalities on stability remains unclear. This study aimed to objectively evaluate patients and without slowing healthy controls. Seventy-three schizophrenia (PS; Salpêtrière Retardation Rating Scale (SRRS) ≥ 15), 25 (non-PS; SRRS < 27 controls (HC) performed four...
There is no authorized treatment for ataxia telangiectasia (AT). As cerebellar symptoms of storage diseases were improved by acetyl-DL-leucine (ADLL), the authors hypothesized a symptomatic and disease-modifying effect in AT upon supplementation with ADLL.Six patients treated ADLL 3 g/day 1 week followed 5g/day weeks to year. Cerebellar was evaluated validated scales. Gaze-holding, saccades smooth pursuit examined video-oculography. Measurements took place at baseline, month therapy 5...
Background A substantial fraction of dizzy patients are assessed by neurologists and ear–nose–throat (ENT) physicians. With the differential diagnosis being broad often different specialties involved, we aimed to assess interaction with generalists from specialists’ perspective identify limitations needs define strategies for improvement in patient care education specialist. Methods One hundred eleven board-certified ( n = 62) ENT physicians 49) working Switzerland participated an online...
The alternate cover test (ACT) in patients with acute vestibular syndrome is part of the 'HINTS' battery test. Although quantitative, ACT highly dependent on examiner's experience and could theoretically vary greatly between examiners. In this study, we sought to validate an automated video-oculography (VOG) system based eye tracking dedicated glasses.We artificially induced a vertical strabismus simulate skew deviation ten healthy subjects, aged from 26 66, using different press-on Fresnel...
Background: Slipped capital femoral epiphyses (SCFE) is associated with out-toeing of the foot and external rotation gait. But it unknown if SCFE patients treated modified Dunn procedure have at follow up. Therefore, we used instrumented gait analysis questioned (1) do severe a symmetrical progression angle (FPA) compared contralateral side asymptomatic volunteers (2) what prevalence are outcome socres Methods: Gait 22 (22 hips) an unilateral for (slip >60 degrees, 2002 to 2011) was...
ABSTRACT In-toeing of the foot was associated with high femoral version (FV), while Out-toeing femoral-retroversion. Therefore, we report on (i) foot-progression-angle (FPA), (ii) prevalence and Out-toeing, (iii) clinical outcome patients treated femoral-derotation-osteotomy (FDO). We performed a retrospective analysis involving 20 (20 hips) unilateral FDO (2017–18). Of them, 14 had increased FV, 6 Follow-up time mean 1 ± years. All minimal 1-year follow-up age 29 8 Patients FV (FV &gt;...
Aims: Aneurysmal subarachnoid hemorrhage (aSAH) accounts for a large proportion of productive life years lost to stroke. Its management requires multidisciplinary effort. Much the presently available data on incidence, treatment, and outcomes come from studies with strong selection bias, confounding all kinds SAH, that is, aneurysmal nonaneurysmal, cohorts single centers or retrospective series. The aim this study is assess treatment modalities, after SAH national registry. Methods: Patients...
When the demands for visual stabilization during head rotations overwhelm ability of vestibuloocular reflex (VOR) to produce compensatory eye movements, brain produces corrective saccades that bring gaze toward fixation target, even without cues (covert saccades). What triggers covert and what might be role prediction in their generation are unknown. We studied 14 subjects with acute vestibular neuritis. To minimize variability stimulus, impulses were imposed a motorized torque generator...
Background Vertigo and dizziness are frequent presenting symptoms in the emergency department outpatient centers. While majority of dizzy patients evaluated by primary care physicians, specialists often involved diagnostic workup. We aimed to gain more insights into role patients. Materials methods Board-certified neurologists ear–nose–throat (ENT) physicians working Switzerland were invited participate an online survey. Descriptive statistical analyses performed, prospectively defined...
Aims: Delayed cerebral vasospasm (dCVS) occurs in more than half of the patients with SAH and is associated delayed neurological deficits (DND) mostly between days 4 15 after ictus. The incidence acute CVS within 72 hours controversial. Acute surgically-induced might influence dCVS outcome undergoing clipping or coiling ruptured unruptured aneurysms. aim this study was to elucidate intraoperative angiographic (iCVS) during aneurysm surgery analyze its possible role on risk for DND.
Aim: Digital subtraction angiography (DSA) is despite invasiveness, costs and possible complications the gold standard for assessment of arterial diameter diagnosis cerebral vasospasm (CVS) after SAH. CT (CTA) a non-invasive first line screening method detecting CVS. However, few validation studies exist comparing results modern CTA DSA devices. In particular, measurements yield absolute values in millimeter, while are generally available pixels or relative units. Our study analyzes...
BACKGROUND Acquired pendular nystagmus (APN) is a back and forth, oscillatory eye movement in which the 2 oppositely directed slow phases have similar waveforms. APN occurs commonly multiple sclerosis causes disabling oscillopsia that impairs vision. Previous studies proven symptomatic therapy with gabapentin or memantine can reduce amplitude frequency. However, effect of these medications on visual acuity (VA) less known to our knowledge impact non-pharmacological strategies such as...