Pooja Makwana

ORCID: 0000-0002-8842-4427
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About
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Research Areas
  • Invertebrate Immune Response Mechanisms
  • Insect Resistance and Genetics
  • Insect symbiosis and bacterial influences
  • Silkworms and Sericulture Research
  • Bone Tissue Engineering Materials
  • Silk-based biomaterials and applications
  • Neurobiology and Insect Physiology Research
  • Insect and Pesticide Research
  • Cancer Cells and Metastasis
  • Insect Utilization and Effects
  • Additive Manufacturing and 3D Printing Technologies
  • 3D Printing in Biomedical Research
  • Nanoparticles: synthesis and applications
  • Plant and Fungal Interactions Research
  • Plant Virus Research Studies
  • Berry genetics and cultivation research
  • Date Palm Research Studies
  • Insect-Plant Interactions and Control
  • Recycling and Waste Management Techniques
  • Electrospun Nanofibers in Biomedical Applications
  • Carcinogens and Genotoxicity Assessment
  • Signaling Pathways in Disease
  • Plant-Microbe Interactions and Immunity
  • Bone Metabolism and Diseases
  • Ethnobotanical and Medicinal Plants Studies

Central University of Gujarat
2021-2024

Central Sericultural Research and Training Institute
2021-2023

Government of India
2023

Seribiotechnology Research Laboratory
2021

Vellore Institute of Technology University
2015

Despite the extensive use of nanoparticles (NPs) in various fields, adequate knowledge human health risk and potential toxicity is still lacking. The lymphocytes play a major role immune system, it can alter antioxidant level when exposed to NPs. Identification hazardous NPs was done using vitro tests this study mainly focuses on comparative cytotoxicity genotoxicity four different including cobalt (II, III) oxide (Co 3 O 4 ), iron (III) (Fe 2 silicon dioxide (SiO aluminum (Al ) lymphocytes....

10.1177/0960327115579208 article EN Human & Experimental Toxicology 2015-03-31

Abstract: Neem ( Azadirachta indica ) is recognized as a medicinal plant well known for its antibacterial, antimalarial, antiviral, and antifungal properties. nanoemulsion (NE) (O/W) formulated using neem oil, Tween 20, water by high-energy ultrasonication. The NE showed antibacterial activity against the bacterial pathogen Vibrio vulnificus disrupting integrity of cell membrane. Despite use in various biomedical applications, toxicity studies on human cells are still lacking. decrease...

10.2147/ijn.s79983 article EN cc-by-nc International Journal of Nanomedicine 2015-10-01

Scaffolds for bone tissue engineering require considerable mechanical strength to repair damaged defects.

10.1039/d4tb00785a article EN Journal of Materials Chemistry B 2024-01-01

Hymenopteran parasitoids inject various factors including polydnaviruses along with their eggs into host insects that suppress immunity reactions to the and larvae. Less is known about mechanisms evolved in dipteran immunity. Here we report dipteran, Exorista bombycis, parasitization leads pro-oxidative activation of anti-oxidative enzymes silkworm Bombyx mori larva. We recorded increased activity oxidase, superoxide dismutase, thioredoxin peroxidase, catalase, glutathione-S-transferase...

10.1002/arch.21373 article EN Archives of Insect Biochemistry and Physiology 2017-01-17

Activation of cellular defence and immunity in the ovary is critical to protect it from pathogenic infection. In this study innate larval pupal ovaries Bombyx mori induced by microsporidian Nosema bombycis reported. Autophagic vacuoles enclosing spores flat cells ovarian disc revealed defence. follicular epithelium differentiated previtellogenic ovarioles infected pupae, a network RER phagosomes observed probably maintain homeostasis. ovaries, paralytic peptide titre, tyrosine content...

10.1080/07924259.2019.1669727 article EN Invertebrate Reproduction & Development 2019-09-26

10.33545/26174693.2024.v8.i11d.2842 article EN International Journal of Advanced Biochemistry Research 2024-11-01

Dipteran endoparasitoids avoid host immune response; however, antidefense components from the Dipterans are unknown. Infestation of commercial silkworm Bombyx mori Linnaeus (Lepidoptera: Bombycidae) by endoparasitoid Exorista bombycis Louis (Diptera: Tachinidae) induced reactions, cytotoxicity, granulation, degranulation, and augmented release cytotoxic marker enzyme lactate dehydrogenase (LDH), degranulation-mediator β-hexosaminidase in hemocytes. In this study, reverse phase...

10.1002/arch.21976 article EN Archives of Insect Biochemistry and Physiology 2022-10-07

Abstract Genome wide gene expression analysis, transcription analysis and mass spectrometry have revealed several uncharacterized genes proteins from commercial silkworm Bombyx mori . Infection of B. larvae with the microsporidian Nosema bombycis induced appearance exclusive in hemocytes showing host response. Mass abundance an protein H9JAZ8 that displayed conserved domains Von Willebrand Factor type D domain (VWF), C8 domain, trypsin inhibitor-like cysteine rich epidermal growth factor...

10.21203/rs.3.rs-2666346/v1 preprint EN cc-by Research Square (Research Square) 2023-05-24
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