A5020704309- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Cancer Cells and Metastasis
- biodegradable polymer synthesis and properties
- Molecular Sensors and Ion Detection
- Advanced Sensor and Energy Harvesting Materials
- Silk-based biomaterials and applications
- Advanced biosensing and bioanalysis techniques
- Luminescence and Fluorescent Materials
- Ionic liquids properties and applications
- Hydrogels: synthesis, properties, applications
- Supramolecular Self-Assembly in Materials
- Cellular Mechanics and Interactions
- Advanced Cellulose Research Studies
- Mesenchymal stem cell research
- X-ray Diffraction in Crystallography
- Bone health and treatments
- Bone Metabolism and Diseases
- Crystallization and Solubility Studies
- Connective tissue disorders research
- Additive Manufacturing and 3D Printing Technologies
- Proteoglycans and glycosaminoglycans research
Central University of Gujarat
2016-2025
Terasaki Foundation
2023-2025
Indian Institute of Technology Kanpur
2005-2014
Casa Sollievo della Sofferenza
2012-2013
University of Milano-Bicocca
2013
Unilever (India)
2010
Skin wound healing involves a coordinated cellular response to achieve complete reepithelialisation. Elevated levels of reactive oxygen species (ROS) in the environment often pose hindrance resulting impaired process. Cerium oxide nanoparticles (CeNPs) have ability protect cells from oxidative damage by actively scavenging ROS. Furthermore, matrices like nanofibers also been explored for enhancing healing. In current study CeNP functionalised polycaprolactone (PCL)-gelatin nanofiber (PGNPNF)...
Severe blood loss due to traumatic injuries remains one of the leading causes death in emergency settings. Chitosan continues be candidate material for hemostatic applications its inherent properties. However, available chitosan-based dressings have been reported an acidic odor at wound site incorporation acid based solvents their fabrication and deformation under compression owing low mechanical strength limiting usability. In present study semi-IPN cryogel was fabricated via Schiff's base...
Blend, coaxial I, II and annealed microchannels were fabricated with an electrospinning setup the fiber morphologies characterized a scanning electron microscope (SEM). Microtubes implanted into rodent spinal cord to analyze biocompatibility.
Osteogenic differentiation is highly correlated with cell morphology. Morphological changes are a stimulus as well consequence of the process. Besides, geometrical, biochemical and mechanical properties substrate can modulate adhesion Therefore, in current study, nanofibrous were used to implement necessary morphology which induced osteogenic without biological supplements. A polycaprolactone-chitosan nanofiber had been fabricated an average diameter ∼75 nm appropriate ratio polymers that...
Highly selective BODIPY-clickates for mercury sensing are reported. These BODIPY clickates exhibits emission in red region with unprecedented large Stokes shifts (116 and 154 nm) upon ion binding due to the intramolecular charge transfer processes.
In the present work, a novel strategy was explored to fabricate nanofiber scaffolds consisting of cellulose assimilated with titanium dioxide (TiO2 ) and silver (Ag) nanoparticles (NPs). The concentration TiO2 NPs in composite adjusted 1.0, 1.5, 2.0 wt % respect polymer used for electrospinning colloidal solutions. fabricated were dispensed alkaline deacetylation using 0.05 M NaOH remove acetyl groups order generate pure nanofibers containing NPs. Moreover, augment our antibacterial...
Scaffolds for bone tissue engineering require considerable mechanical strength to repair damaged defects.
Fluorescent therapeutic molecules offer a unique platform to study cellular uptake and biological pathways of drug candidates. Inhibition the p53-HDM2 protein complex with reactivation p53 pathway...
Dental implant failure, often due to bone resorption and poor osteointegration, can be mitigated using barrier membranes prevent non‐osteogenic tissue interference during healing. In addition the existing membranes, guided regeneration has opened new avenues for membrane design, allowing them actively participate in rather than merely serving as barriers. this context, aim of study was fabricate a composite that mimic native extracellular matrix tissue. The novel containing chitosan,...
Smart biomaterials have significantly impacted human healthcare by advancing the development of medical devices designed to function within tissue, mimicking behavior natural tissues. While intelligence has evolved from inert active over past few decades, smart take this a step further making their surfaces or bulk respond based on interactions with surrounding tissues, imparting outcomes similar tissue functions. This interaction helps in creating stimuli-responsive biomaterials, which can...
The importance of self-assembling peptides (SAPs) in regenerative medicine is becoming increasingly recognized. propensity SAPs to form nanostructured fibers governed by multiple forces including hydrogen bonds, hydrophobic interactions and π-π aromatic among side chains the amino acids. Single residue modifications SAP sequences can significantly affect these forces. BMHP1-derived a class biotinylated oligopeptides, which self-assemble β-structured self-healing hydrogel. In current study,...
Bone regeneration is a multi-step, overlapping process, in which angiogenesis and osteogenesis are the key players. Several attempts have been made to promote angiogenesis-coupled using scaffolding technology. However, recreation of functional vasculature during bone an unparalleled challenge. In this study, dual drug-delivering polycaprolactone-collagen fibrous scaffold reported early angiogenesis. Simvastatin as pro-angiogenic dexamethasone osteoinductive drug were encapsulated...