A5046749336- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Micro and Nano Robotics
- Cell Image Analysis Techniques
- Electrohydrodynamics and Fluid Dynamics
- Microfluidic and Capillary Electrophoresis Applications
- Electrospun Nanofibers in Biomedical Applications
- Neuroscience and Neural Engineering
- Electrochemical sensors and biosensors
- RNA Interference and Gene Delivery
- Tissue Engineering and Regenerative Medicine
- Barrier Structure and Function Studies
- Advanced Sensor and Energy Harvesting Materials
- Graphene and Nanomaterials Applications
- Mathematical Biology Tumor Growth
- Cancer Cells and Metastasis
- Ocular Oncology and Treatments
- Glioma Diagnosis and Treatment
- Pickering emulsions and particle stabilization
- Nanoparticle-Based Drug Delivery
- Microfluidic and Bio-sensing Technologies
- Block Copolymer Self-Assembly
- Nanofabrication and Lithography Techniques
- Retinal and Macular Surgery
- Ocular Infections and Treatments
Duke University
2024-2025
Terasaki Foundation
2022-2024
Indian Institute of Technology Guwahati
2018-2023
Assam University
2021
Smart biomaterials have significantly impacted human healthcare by advancing the development of medical devices designed to function within tissue, mimicking behavior natural tissues. While intelligence has evolved from inert active over past few decades, smart take this a step further making their surfaces or bulk respond based on interactions with surrounding tissues, imparting outcomes similar tissue functions. This interaction helps in creating stimuli-responsive biomaterials, which can...
Nanoscale copper oxide (CuO NPs) with diameters in the 80–150 nm range has been biosynthesized using lipopeptide biosurfactant derived from Bacillus vallismortis and characterized by XRD FE-SEM. The CuO NPs could be introduced as nanocarrier systems for combination therapy a potential candidate antibacterial, antioxidant, anticancer, anti-diabetic activity. antibacterial activity of was studied incorporating nanoparticles fluorescent antibiotic Ciprofloxacin HCL (CIP) to form CIP@CuO tracked...
Treatment of persistent biofilm infections has turned out to be a formidable challenge even with broad-spectrum antibiotic therapies. In this direction, intelligent micromachines may serve as active mechanical means dislodge such deleterious bacterial communities. Herein, we have designed biocompatible micromotors from tea buds, namely, T-Budbots, which shows the capacity magnetically driven on matrix and remove or fragment biofilms precision, part proposed non-invasive "Kill-n-Clean"...
Glioblastoma Multiforme (GBM) represents a significant clinical challenge amongst central nervous system (CNS) tumors, with dismal mean survival rate of less than 8 months, statistic that has remained largely unchanged for decades (National Brain Society, 2022). The specialized intricate anatomical features the brain, notably blood-brain barrier (BBB), pose challenges to effective therapeutic interventions, limiting potential reach modern advancements in immunotherapy impact these types...
ABSTRACT Background Embolization is a well-established treatment modality for liver cancer. However, traditional embolization agents are limited by inefficient delivery and aggregation in blood vessels. Novel shear-thinning hydrogels (STH) have been developed to address the need safer more effective local of embolic therapeutics. Objective We aim evaluate efficacy novel such as STH using human-relevant vitro model that recapitulates human hepatocellular carcinoma capillary networks. Methods...
Multifunctional chemically powered micromotors were fabricated from the airborne contaminant carbon soot (CS) for environmental remediation following two approaches: first, by physical deposition of catalytic platinum (Pt) and magnetic nickel (Ni) nanoscale films ∼110 nm ∼100 nm, respectively, on CS (CARBOts) second, chemical magneto-catalytic iron nanoparticles (FeNPs) ∼30 or less in size surface (iCARBOts). The synthesis nanoparticle (FeNPs)-based iCARBOts provides an economical...
Quantification of β-2-microglobulin (B2M) in human tear can help detecting the onset and growth dreaded eye disease diabetic retinopathy (DR) for patients suffering from diabetes mellitus. In this direction, a biosensor has been developed point-of-care (POC) estimation B2M, suitable early detection regular monitoring DR. The immunosensor is composed water-based suspension gold nanoparticles (AuNPs) coated with anti-β-2-microglobulin (anti-B2M) using linker, which shows specific coloration...
We explore the salient features of electroosmotic flow inside patterned and deformable microchannels. A computational fluid dynamic simulator is developed to solve coupled Poisson's equation for electrolyte, Laplace external electric field, continuity momentum equations flow, with appropriate boundary conditions. The simulations reveal existence some exceptional profiles variations in normalized Debye length, dimensions, locations heterogeneities, strength deformability walls. surface...
Abstract We report the development of a 3G microswimmer, namely, CNT-bot, capable undergoing acid-, alkali-, magneto- and phototaxis inside acidic or alkaline baths peroxide fuel and/or water. The use carboxyl-functionalised multi-walled carbon nanotubes (MWCNTs) facilitated propulsion CNT-bots in an alkaline-water solution by ejecting carbon-dioxide bubbles. Furthermore, doping magnetite nanoparticles (FeONPs), ferrous ions (Fe 2+ ) titanium dioxide (TiONPs) induces magnetic, chemical...
This study reveals various unexplored pathways to energy storage in parallel and curved plate supercapacitors (SCs). The spatiotemporal variations the electric field intensity of such SCs were found have a significant influence on their performance. observations unearth limitations associated with previous theoretical models, which are routinely employed analyze performance by considering electrical double layers (EDLs) as capacitors near electrodes. time-dependent electrochemical behaviors...
Storage and transport of H<sub>2</sub>O<sub>2</sub>microdroplets using magnetic liquid marbles: from oil spill recovery to antibacterial applications.
Abstract Thiazolidin‐4‐one is a versatile nucleus that has been reported to exhibit diverse array of biological activities, including anticancer and antimicrobial activities. In the current research study, series C2 ‐( p ‐substituted phenyl)‐thiazolidin‐4‐one compounds conjugated with anilines were designed tested for drug‐likeness behaviour. Subsequently, synthesized, characterized, activity against three cancer cell lines, namely liver (HEP−G2 cells), breast (MDA‐MB‐231), glioblastoma...
We explore the improvements in yield and conversion of a chemical reaction inside two-phase microfluidic reactor when subjected to an externally applied alternating current (AC) electric field. A computational fluid dynamic (CFD) framework has been developed incorporate descriptions flow, multicomponent transport reaction, Maxwell's stresses generated at oil-water interface owing presence The CFD model ensures that reactants are flown into microchannel together with oil water phases before...
Abstract Triple‐negative breast cancer develops from malignant cells within the interior lining of milk ducts or, less frequently, in stromal tissues and accounts for ≈15% all cancers. Breast is highly prevalent with overall number cases expected to reach 27.78 million by 2040, according World Health Organization. MiRNAs serve a novel role management through their ability indirectly control translation coding mRNA regulate expression specific genes, which allows it play significant...