A5007675539- Photochemistry and Electron Transfer Studies
- Hemoglobinopathies and Related Disorders
- Fullerene Chemistry and Applications
- Synthesis and Properties of Aromatic Compounds
- Organic Electronics and Photovoltaics
- Porphyrin and Phthalocyanine Chemistry
- Organic Light-Emitting Diodes Research
- Enzyme-mediated dye degradation
- Luminescence and Fluorescent Materials
- Advanced Chemical Physics Studies
- Blood groups and transfusion
- Molecular Junctions and Nanostructures
- Iron Metabolism and Disorders
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- T-cell and B-cell Immunology
- Advanced Nanomaterials in Catalysis
- Electrochemical Analysis and Applications
- Ionic liquids properties and applications
- Complement system in diseases
- Advanced Measurement and Metrology Techniques
- Genomics and Rare Diseases
- Chemical Reactions and Mechanisms
- Receptor Mechanisms and Signaling
- Lipid metabolism and disorders
- Advanced machining processes and optimization
Osaka University
2014-2024
Affiliated Hospital of Jiangsu University
2024
Jiangsu University
2024
Shanghai University of Engineering Science
2015
Shanghai University
2011-2012
Centre International de Recherches Médicales de Franceville
2003
Inserm
1992-2001
Hôpital Robert-Debré
1992-2001
National Institute of Immunohaematology
2000
Hôpital Saint-Louis
1995
Cycloparaphenylenes (CPPs), a class of hoop-shaped conjugated macrocycles, have attracted the attention researchers in various fields because their interesting properties. Although properties singlet-excited state been reported, there is no systematic information on triplet-excited state. In present study, [n]CPP (n = 8–12, where n denotes number phenyl rings) were comprehensively investigated. The phosphorescence peak shifted to shorter-wavelength side with increasing ring size CPPs,...
Excited radical ions are interesting reactive intermediates owing to powerful redox reactivities, which applicable various reactions. Although their reactivities have been examined for many years, dynamics not well-defined. In this study, we intermolecular and intramolecular electron transfer (ET) processes from excited anions of naphthalene-1,4,5,8-tetracarboxydiimide (NDI•–*). Intermolecular ET between NDI•–* acceptors were confirmed by transient absorption measurements during laser flash...
Radical anions in the excited states can be treated as stronger reductants than those ground states. In this study, intramolecular electron transfer (ET) processes from perylene-3,4,9,10-tetracarboxydiimide radical anion (PDI•–*) were examined for first time by applying femtosecond laser flash photolysis to dyads of PDI and acceptors (PDI-A). Efficient ET PDI•–* was detected upon excitation PDI•–-pyromellitimide (PI) PDI•–-naphthalenediimide (NDI) because sufficient driving forces....
Familial hyperlipidemia (familial hypercholesterolemia, FH) is an autosomal genetic disorder. It includes type heterozygous familial (heterozygous hypercholesterolemia). HeFH mainly caused by mutations in the LDLR, APOB, and PCSK9 genes characterized elevated plasma low-density lipoprotein cholesterol levels. We present a case of attributed to APOB gene mutation. The whole-genome DNA peripheral blood was extracted from proband their parents, exons were sequenced through high-throughput...
Intramolecular electron transfer (ET) processes in the excited aromatic diimide bis(radical anion)s (ADI•–*–ADI′•–) were systematically investigated by applying femtosecond laser flash photolysis to of naphthalenediimide (NDI) and perylenediimide (PDI), including NDI•––m-NDI•–, NDI•––p-NDI•–, PDI•––m-PDI•–, NDI•––m-PDI•– (m p indicate substitution positions). The excitation NDI•––m-NDI•– NDI•––p-NDI•– initiated disproportionation reactions generating NDI NDI2– with different ET rate...
[n]Cycloparaphenylenes ([n]CPPs; n, number of phenyl rings) have gained considerable attention because they exhibit interesting properties owing to their highly strained structure and radially oriented p orbitals. Recently, [n]CPPs with n ≥ 5 been synthesized, but the ring-size dependence deactivation processes excited states has not explained particularly for smaller (n ≤ 7). In present study, we characterized (5 12) using transient absorption spectroscopy at sub-pico-, sub-nano-, nano-,...
Abstract Sixty‐four homozygous β‐thalassemia patients comprising 40 with major and 24 intermedia were investigated for the nature of their mutations, associated α‐thalassemia, Xmn I polymorphism in gamma gene which are known to affect clinical course disease. This study was undertaken look contribution these factors reducing severity from a severe disease phenotype. Clinical assessed by degree transfusion dependency age at patient presented symptoms. Globin chain synthetic ratio taken as...
Klebsiella oxytoca mutants resistant to a variety of beta-lactams were obtained in vitro on aztreonam. Constitutive beta-lactamase production was much higher the than susceptible strains (75-fold). The only difference observed these compared with point mutations Pribnow box: transversion (G-->T) first base for one mutant or transition (G-->A) fifth -10 consensus sequence other three mutants. transcriptional output gene (blaOXY) from significantly that blaOXY strains.
Paracyclophanes (PCPs), which exhibit interesting properties due to their transannular interactions, have been employed as a spacer in various electron transfer (ET) systems. In the present work, we investigated ET processes dyads and triads containing [2.2]PCP or [3.3]PCP donors study multistep processes. The dyad molecules of PCP 1,8-naphthalimide (NI) photosensitizing acceptor exhibited charge separation (CS) upon excitation NI. addition, NI, PCP, carbazole showed shift after an initial...
A new series of mesitylene-linked oligothiophenes (nT, n is the number thiophene units), including 2T-M, 3T-M, 4T-M, 4T-M-2T, and 4T-M-3T, was prepared to investigate intramolecular hole transfer (HT) from excited radical cation for first time. The results spectroscopic theoretical studies indicated that mesitylene acts as a spacer minimizing perturbation π-conjugation increasing stability nT cations (nT•+). Femtosecond laser flash photolysis applied FeCl3-oxidized 4T•+-M, 4T•+-M-2T,...
Over the last few years, substantial progress has been made in developing strategies for detection and characterization of various mutations causing β-thalassemia. The Indian population comprises numerous endogamous caste groups β-thalassemia is seen almost all them. Knowledge spectrum a prerequisite successful implementation prevention programme. Among different approaches available today, Denaturing Gradient Gel Electrophoresis (DGGE) offers valid technical approach which applicable...
Excited-state dynamics of the C70 radical anion (C70•–*) were investigated for first time by applying femtosecond laser flash photolysis to reduced and its derivatives, including C70•–, C70H•–, C70•–-pyromellitimide (PI), C70•–-naphthalenediimide (NDI)•–. The transient absorption spectra C70•– C70H•– upon near-infrared excitation revealed relaxation processes D1 vibrational hot ground (D0hot) states. Chemical modification was found decrease excited-state lifetimes. In cases dyad molecules...
Size-dependent properties of the excited dications [<italic>n</italic>]cycloparaphenylenes were analysed on basis structural relaxation.
The properties of the excited perylenediimide dianion (PDI
AbstractThe electrodeposition of nano-iron films from Fe2O3 precursor in an ionic liquid composed 33·3 mol-% choline chloride (ChCl) and 66·7 ethylene glycol (EG) has been investigated. The process was carried out at 1·5–1·9 V 60–120°C for 3 hours. influences experimental parameters on the morphology deposited were studied. results show that compact uniform (particle size is approximately 100–200 nm) can be electrodeposited Fe2O3-saturated ChCl-EG 1·8–1·9 60–120°C. temperature applied...
For the first time, dynamics of excited fullerene dianions and associated intramolecular electron transfer (ET) were directly investigated by using femtosecond pump-probe laser flash photolysis on selectively reduced C60, pyrrolidino[60]fullerene (C60H), dyads including C60-naphthalenediimide (NDI) C60-pyromellitimide (PI). Upon near-infrared excitation, dianion C60 or C60H displayed two states with lifetimes less than one several tens ps, attributed to prompt internal conversion from...