A5003930976- Mobile Ad Hoc Networks
- Opportunistic and Delay-Tolerant Networks
- Wireless Networks and Protocols
- Bone Metabolism and Diseases
- Cooperative Communication and Network Coding
- Smart Grid Security and Resilience
- Vehicular Ad Hoc Networks (VANETs)
- bioluminescence and chemiluminescence research
- Optical Coherence Tomography Applications
- Wnt/β-catenin signaling in development and cancer
- Nanofabrication and Lithography Techniques
- Cell Adhesion Molecules Research
- Nanoplatforms for cancer theranostics
- Software-Defined Networks and 5G
- Esophageal Cancer Research and Treatment
- Photodynamic Therapy Research Studies
- Inflammatory mediators and NSAID effects
- dental development and anomalies
- Photonic and Optical Devices
- VLSI and Analog Circuit Testing
- Bone Tissue Engineering Materials
- Bluetooth and Wireless Communication Technologies
- Cellular Mechanics and Interactions
- Hematopoietic Stem Cell Transplantation
- Bone fractures and treatments
Seoul National University
2024
Korea Advanced Institute of Science and Technology
2015-2021
Zero to Three
2021
Korea Electric Power Corporation (South Korea)
2018
Ajou University
2011-2016
Qatar Mobility Innovations Center
2015
Qatar Science and Technology Park
2015
Keimyung University Dongsan Medical Center
2014
Keimyung University
2014
PerkinElmer (United States)
2012
Tissue regeneration is increasingly viewed as reactivation of a developmental process that, when misappropriated, can lead to malignant growth. Therefore, understanding the molecular and cellular pathways that govern tissue provides glimpse into normal development well insights pathological conditions such cancer. Herein, we studied role Wnt signaling in skeletal regeneration.Some adult tissues have ability regenerate, among these, bone one most remarkable. Bone exhibits persistent, lifelong...
E- and N-cadherin are members of the classical cadherin family proteins. E-cadherin plays an important role in maintaining normal phenotype epithelial cells. Previous studies from our laboratory other laboratories have shown that inappropriate expression by tumor cells derived tissue results conversion cell to a more fibroblast-like cell, with increased motility invasion. Our present study was designed determine which domains make it different E-cadherin, respect altering cellular behavior,...
Several investigations have demonstrated a precise balance to exist between bone morphogenetic protein (BMP) agonists and antagonists, dictating BMP signaling osteogenesis. We report novel approach manipulate activity through down-regulation of the potent antagonist Noggin, examined effects on forming capacity osteoblasts. Reduction noggin enhanced in vitro osteoblast formation, as by both gene expression profiles histological staining. The suppression vivo formation were also investigated...
Early detection of tumors can significantly improve the outcome tumor treatment. One most frequently asked questions in cancer imaging is how many cells be detected non-invasively a live animal. Although factors limit such detection, increasing light emission from one effective ways overcoming these limitations. Here, we describe development and utilization lentiviral vector containing enhanced firefly luciferase (luc2) gene. The resulting single cell clones mouse mammary gland (4T1-luc2)...
A challenge faced by smart grid systems is providing highly reliable transmissions to better serve different types of electrical applications and improve the energy efficiency system. Although wireless networking technologies can provide highspeed cost-effective solutions, their performance may be impaired various factors that affect reliability networks. Here, we first suggest use IEEE 802.11s-based LAN mesh networks as high-speed backbone for infrastructure high scalability flexibility...
The majority of cells are equipped to detect and decipher physical stimuli, then react these stimuli in a cell type-specific manner. Ultimately, cellular behaviors synchronized produce tissue response, but how this is achieved remains enigmatic. Here, we investigated the genetic basis for mechanotransduction using bone marrow as model system. We found that produced pattern principal strain precisely corresponded site-specific expression sox9 runx2, two transcription factors required...
Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific agonists method for in vivo delivery purified proteins. Wnts contain lipid adducts that are required activity we exploited this lipophilicity by packaging Wnt3a protein into vesicles. Rather than being encapsulated, tethered to the liposomal surface, where they enhance sustain signaling vitro. Molecules effectively antagonize soluble but ineffective against...
Smart grid environments require high standard of reliable transmission technologies to support various types electrical services and applications. This paper recommends the utilization IEEE 802.11s based Wireless LAN Mesh Networks as high-speed backbone networks for smart infrastructure. mesh can provide scalability flexibility, along with low installation management costs. We also describe some challenging issues WLAN networks, propose two novel methods improving their routing reliability....
Abstract An endomicroscope opens new frontiers of non-invasive biopsy for in vivo imaging applications. Here we report two-photon laser scanning cellular and tissue using a Lissajous fiber scanner. The scanner consists piezoelectric (PZT) tube, single double-clad (DCF) with high fluorescence collection, micro-tethered-silicon-oscillator (MTSO) the separation biaxial resonant frequencies. endomicroscopic exhibits 5 frames/s 99% density by selection rule was compactly packaged within stainless...
As the size and complexity of SoC design grow, an efficient structured verification environment is becoming more important than ever before. It because many engineers with different knowledge skills are involved in verification, they have to deal aspects verification. This paper looks over diversity suggests a practical application method UVM (Universal Verification Methodology) build which meets various requirements shows standardized well-organized testbench architecture that includes...
OpenFlow is the first standard interface for realizing Software-Defined Networking (SDN) that can decouple data and control plane to provide scalable network management. To validate performance features of standard, many researchers have utilized specialized hardware devices such as NetFPGA. However, these are not suitable implementing a small-scale SDN testbed due high cost, complexity, programming languages. The well-known emulator, Mininet[l], also widely but it enough support dynamicity...
Context and situational awareness are key features trends of the smart grid enable adaptable, flexible extendable services. However, traditional hardware-dependent communication infrastructure is not designed to identify flow context data, it focuses only on packet forwarding using a pre-defined network configuration profile. Thus, current may dynamically adapt various business models services system. To solve this problem, software-defined networking (SDN) being considered in grid, but...
Osteoblasts are derived from two distinct embryonic lineages: cranial neural crest, and mesoderm. Both populations of cells capable forming bone cartilage during fetal development adult repair, but whether they use equivalent molecular pathways to achieve osteoblast differentiation is unknown. We addressed this question in the context repair focused on role Wnt signaling mandibular skeletal healing. Transgenic reporter mice were used pinpoint Wnt-responsive injury callus, situ hybridization...
We report a facile and direct fabrication method for integrating functional optical microstructures on the top surface of an fiber. A programmable maskless system was developed by using digital micromirror device (DMD), which allows rapid prototyping low-cost without physical photomask. This UV exposure has spatial resolution 2.2 μm exposed area 245 x 185 μm. Diverse were photolithographically defined multimode fibers single mode fiber serially spliced with coreless silica segment. provides...
To reveal, on a cellular and molecular level, how skeletal regeneration of corticotomy is enhanced when using laser-plasma mediated ablation compared with conventional mechanical tissue removal.Osteotomies are well-known for their most detrimental side effect: thermal damage. This trauma to adjacent bone can result in the untoward consequences cell death eventually delay healing.Murine tibial corticotomies were performed saw Ti:Sapphire plasma-generated laser that removes minimal Our...
We report a fiber-optic plasmonic probe with nanogap-rich gold nanoislands for on-site surface-enhanced Raman spectroscopy (SERS). The features Au on the top surface of single multimode fiber. were monolithically fabricated using repeated solid-state dewetting thermally evaporated thin film. shows 7.8 × 106 in SERS enhancement factor and 100 nM limit-of-detection crystal violet under both excitation laser light collection signals through optical fiber-through measurement also demonstrates...
Implementing 3D surface imaging camera systems into miniaturized devices for a variety of applications such as movement recognition, object sensing, and endoscopy has received great attention over the past decade. Recently, various MEMS techniques enabled fabrication key optical elements with compact size, reasonable cost, high yield. This article will overview principles major categories their using camera.
Abstract This article reports the diffractive optical elements of rotational offset microlens arrays for generating highly efficient structured light patterns in active stereoscopic 3D imaging. The double‐side configuration increases uniformity diffraction by using two successive refractions on surfaces. In addition, offsets between frontside and backside with rectangular or hexagonal arrangements control contrast density dot array patterns. Two layers high curvature fill‐factor are...
Advanced Metering Infrastructure (AMI) network is the capillary communication for smart grid that does not only provide data collection from each household but also delivers configuration requests intelligent energy services. However, challenges like heterogeneity, large-scale, and distributed operation must be solved reliable stable Software defined networking (SDN) can help improving scalability consistency issues by separating control planes, it needs to optimized resource-constrained AMI...
Today system-on-a-chip (SoC) is like a black hole which draws all the important IP/cores in digital system. Current SoC design methodologies are no longer adequate to meet challenges of productivity, quality and diminishing time-to-market window. This paper describes an innovative platform integration verification methodology enhance productivity based on IP reuse IP-XACT standard. Platform integrator including RPTKit (reusable toolkit) developed improve efficiency reliability integration,...