Helen Poulsen

ORCID: 0000-0002-8877-3109
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Forensic Toxicology and Drug Analysis
  • Cannabis and Cannabinoid Research
  • Substance Abuse Treatment and Outcomes
  • Traffic and Road Safety
  • Alcohol Consumption and Health Effects
  • Biosensors and Analytical Detection
  • Advanced biosensing and bioanalysis techniques
  • Neurotransmitter Receptor Influence on Behavior
  • Cassava research and cyanide
  • Plant Parasitism and Resistance
  • Higher Education Governance and Development
  • Opioid Use Disorder Treatment
  • Mass Spectrometry Techniques and Applications
  • Electrochemical sensors and biosensors
  • Gold and Silver Nanoparticles Synthesis and Applications
  • GABA and Rice Research

Institute of Environmental Science and Research
2012-2024

Colorimetric gold-nanoparticle-based biosensors are an attractive platform for the detection of small-molecule analytes. Taking advantage adsorption DNA aptamer probes on AuNPs, these sensors can be simple, rapid, sensitive, selective, and cost-effective. These properties important rapid drugs like methamphetamine in biological matrices. Saliva is a highly desirable matrix development diagnostic tests because saliva sampling minimally invasive drug levels relate to recent use rather than...

10.1021/acssensors.3c00310 article EN ACS Sensors 2023-04-02

Abstract We describe the validation of a method for simultaneous analysis 29 synthetic cannabinoids (SCs) and metabolites, 4 amphetamines, 2 in human whole blood. This enables one to cover what previously required multiple analyses these classic novel drugs‐of‐abuse with diverse physicochemical properties. The scope targeted analytes was based on most prevalent SCs encountered at New Zealand border 2017 included parent compounds metabolites belonging indole indazole carboxamide, quinolinyl...

10.1002/dta.2697 article EN Drug Testing and Analysis 2019-10-09

Abstract This report details the toxicology profile of victims drug-facilitated sexual assault (DFSA) in New Zealand from 2015 to 2018. study represents all results for DFSA cases during this time period, which there were 161 cases. Blood and urine samples screened legal illicit drugs addition testing alcohol correlating concentration with sampling delay. Our indicate that increased delay resulted a corresponding decrease concentration. In who had declared use but none was detected, average...

10.1093/jat/bkz110 article EN Journal of Analytical Toxicology 2020-03-10

DNA aptamers have emerged as promising probes for challenging analytes that cannot be easily detected by conventional probes, including small-molecule targets. Among the different signal transduction approaches, gold nanoparticle (AuNP) aggregation assays been widely used to generate a colorimetric response from aptamer–target interactions. This sensor design relies on competition between aptamer adsorbing AuNP surface versus interacting with target, whereby target binding reduces number of...

10.1021/acsami.2c04747 article EN ACS Applied Materials & Interfaces 2022-07-14

Abstract In December 2014, the legal blood alcohol limit for drivers in both Scotland and New Zealand was reduced from 80 to 50 mg/100 mL . This paper reports a retrospective study comparing changes toxicological findings deceased motorcyclists before after change jurisdictions. A year of fatal motor vehicle crashes prior following is examined countries. Scotland, there an increase drug prevalence among fatally injured motorcyclists, with use all groups increasing change, exception...

10.1111/1556-4029.13747 article EN Journal of Forensic Sciences 2018-01-26

Frustration at the restrictions to access prescribed cannabinoids in New Zealand has resulted a black market of home-made cannabis-based products for medicinal use. These are being made, and marketed illegally, by individuals calling themselves ‘Green Fairies’. The take many forms used treat range illnesses symptoms including pain, insomnia, anxiety, seizures. Analytical extraction methods were developed determine cannabinoid content variety matrices, principally those that soluble methanol...

10.1071/ch21001 article EN Australian Journal of Chemistry 2021-05-25

Objective This study examined the prevalence of use prescription medicines and other drugs by a selected subgroup New Zealand drivers. The potentially impairing driving population is largely unknown. studied was drivers who were stopped police, failed breath alcohol test, elected to provide blood sample for laboratory analysis, had levels exceeding legal limit.

10.1080/15389588.2024.2418361 article EN Traffic Injury Prevention 2024-11-29
Coming Soon ...