Zhongguo Wang

ORCID: 0000-0002-8886-8669
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Research Areas
  • Advanced Cellulose Research Studies
  • Advanced Sensor and Energy Harvesting Materials
  • Hydraulic Fracturing and Reservoir Analysis
  • Electrospun Nanofibers in Biomedical Applications
  • Biochemical and Molecular Research
  • Membrane Separation and Gas Transport
  • Oil and Gas Production Techniques
  • Solar Thermal and Photovoltaic Systems
  • Sirtuins and Resveratrol in Medicine
  • Drilling and Well Engineering
  • Metal-Organic Frameworks: Synthesis and Applications
  • Aerosol Filtration and Electrostatic Precipitation
  • Aerogels and thermal insulation
  • Supercapacitor Materials and Fabrication
  • Surface Modification and Superhydrophobicity
  • Solar-Powered Water Purification Methods
  • Reservoir Engineering and Simulation Methods
  • Membrane Separation Technologies
  • Catalytic Alkyne Reactions
  • Dielectric materials and actuators
  • Cyclization and Aryne Chemistry
  • Biofuel production and bioconversion
  • Gas Sensing Nanomaterials and Sensors
  • Nanocomposite Films for Food Packaging
  • Cancer, Hypoxia, and Metabolism

Liaocheng University
2023-2025

Nanjing Forestry University
2018-2023

Shenzhen Institutes of Advanced Technology
2020-2022

Central China Normal University
2020-2022

Nanyang Normal University
2022

Chinese Academy of Sciences
2020-2022

Suzhou University of Science and Technology
2022

University of Science and Technology of China
2020-2022

Anhui Institute of Information Technology
2021-2022

Institute of Information Engineering
2021

Abstract Inspired by the anti‐freezing mechanisms found in nature, ionic compounds (ZnCl 2 /CaCl ) are integrated into cellulose hydrogel networks to enhance freezing resistance. In this work, cotton is dissolved a specially designed ZnCl system, which endows hydrogels specific properties such as excellent freeze‐tolerance, good ion conductivity, and superior thermal reversibility. Interestingly, rate of coagulation could be promoted addition extra water or glycerol. This new type...

10.1002/anie.201902578 article EN Angewandte Chemie International Edition 2019-04-02

10.1016/j.ijbiomac.2023.123425 article EN International Journal of Biological Macromolecules 2023-01-25

Inhibition of mutant IDH1 is being evaluated clinically as a treatment option for oncology. Here we describe the structure-based design and optimization quinoline lead compounds to identify FT-2102, potent, orally bioavailable, brain penetrant, selective mIDH1 inhibitor. FT-2102 has excellent ADME/PK properties reduces 2-hydroxyglutarate levels in an xenograft tumor model. This compound been selected candidate clinical development hematologic malignancies, solid tumors, gliomas with mIDH1.

10.1021/acs.jmedchem.9b01423 article EN Journal of Medicinal Chemistry 2020-01-23

This review emphasizes the recent advances in synthesis strategies, versatile structures and broad applications of cellulose-metal organic framework composites.

10.1039/d1ta06468a article EN Journal of Materials Chemistry A 2021-01-01

Thin, lightweight, and flexible textile pressure sensors with the ability to detect full range of faint (<100 Pa), low (≈KPa) high (≈MPa) are in significant demand meet requirements for applications daily activities more meaningfully some harsh environments, such as temperature pressure. However, it is still a challenge fulfill these simultaneously single sensor. Herein, high-performance sensor enabled by polyimide fiber fabric functionalized carbon-nanotube (PI/FCNT) obtained via facile...

10.1002/advs.202105738 article EN Advanced Science 2022-03-14

Crystal structures of several urea- and thiourea-derived compounds in complex with the nicotinamide phosphoribosyltransferase (Nampt) protein were utilized to design a potent amide-containing inhibitor bearing an aza-indole moiety (7, Nampt BC IC50 = 9.0 nM, A2780 cell proliferation 10 nM). The Nampt–7 cocrystal structure was subsequently obtained enabled additional inhibitors which incorporated various other fused 6,5-heterocyclic moieties biaryl sulfone or sulfonamide motifs. Additional...

10.1021/jm4008664 article EN Journal of Medicinal Chemistry 2013-07-16
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