A5023527016- Gene Regulatory Network Analysis
- Cellular Mechanics and Interactions
- Lipid Membrane Structure and Behavior
- Light effects on plants
- Nonlinear Dynamics and Pattern Formation
- Ethics and bioethics in healthcare
- Plant and Biological Electrophysiology Studies
- Circadian rhythm and melatonin
- Accounting and Financial Management
- Biocrusts and Microbial Ecology
- Cell Image Analysis Techniques
- Mathematical Biology Tumor Growth
- Neurobiology and Insect Physiology Research
- Biomedical Text Mining and Ontologies
- Micro and Nano Robotics
- Magnetic confinement fusion research
- Social Issues and Policies in Latin America
- Bacterial biofilms and quorum sensing
- Intelligent Tutoring Systems and Adaptive Learning
- E-Learning and Knowledge Management
- Microtubule and mitosis dynamics
- Agricultural and Food Production Studies
- Protist diversity and phylogeny
- Wind Energy Research and Development
- Cerebrospinal fluid and hydrocephalus
Lindsay Unified School District
2024
Oregon Medical Research Center
2024
New York Proton Center
2024
University of Pittsburgh
2024
Communities In Schools of Orange County
2024
École Polytechnique Fédérale de Lausanne
2019-2023
Max Planck Institute for the Physics of Complex Systems
2020-2021
Escuela Superior Politécnica del Chimborazo
2021
Max Planck Institute for Dynamics and Self-Organization
2013-2020
Max Planck Society
2013
Significance Single cells across kingdoms of life explore, prey, escape, or congregate using surface-specific motility. Motile eukaryotic use chemotaxis to direct migration on surfaces. However, how bacteria control surface motility remains underexplored. Pseudomonas aeruginosa twitches surfaces by successive extension and retraction extracellular filaments called type IV pili. Here, we show that P. directs twitching sensing mechanical input generated The Chp sensory system performs...
The rapid reorganization of the actin cytoskeleton in response to external stimuli is an essential property many motile eukaryotic cells. Here, we report evidence that machinery chemotactic Dictyostelium cells operates close oscillatory instability. When averaging a short pulse chemoattractant cAMP, observed transient accumulation cortical reminiscent damped oscillation. At single-cell level, however, dynamics ranged from short, strongly responses slowly decaying, weakly oscillations....
Abstract We present a general theory of noisy genetic oscillators with externally regulated production rate and multiplicative noise. The observables that characterize the oscillator are discussed, it is shown how their statistics depend on rate. show these have generic features observed in two different experimental systems: expression circadian clock genes fibroblasts, transient oscillatory dynamics segmentation cells disassociated from zebrafish embryos. Our work shows oscillations...
AbstractAn investigation of the relationship between amplitudes and rise times miniature end-plate potentials recorded from neuromuscular junctions frog sartorius has shown existence a positive correlation these two parameters. This finding is consistent with occurrence process "spreading activation", i.e. progressive recruitment receptors by wave acetylcholine molecules diffusing tangentially within synaptic space. It appears that initial concentration transmitter cleft must be large enough...
This paper presents full cross-section measurements of drift waves in the linear magnetized plasma Mirabelle device. Drift wave modes are studied regimes weakly developed turbulence. The develop azimuthal space-time structures density, potential, and visible light fluctuations. A fast camera diagnostic is used to record fluctuations column an cross section with a temporal resolution $10\phantom{\rule{0.28em}{0ex}}\phantom{\rule{4pt}{0ex}}\ensuremath{\mu}\mathrm{s}$ corresponding...
Biological systems with their complex biochemical networks are known to be intrinsically noisy. Here we investigate the dynamics of actin polymerization amoeboid cells, which close onset oscillations. We show that large phenotypic variability in can accurately captured by a generic nonlinear oscillator model presence noise. determine relative role noise single dimensionless, experimentally accessible parameter, thus providing quantitative description population cells. Our approach, rests on...
Spatiotemporal splitting events of drift wave (DW) eigenmodes due to nonlinear coupling are investigated in a cylindrical helicon plasma device. DW the radial-azimuthal cross section have been experimentally observed split at radial locations and recombine into global eigenmode with time shorter than typical period (t≪fDW(-1)). The number splits correlates increase turbulence. dynamics can be theoretically reproduced by Kuramoto-type model network radially coupled azimuthal eigenmodes....
ABSTRACT The Company of Biologists’ 2022 workshop on ‘Cell State Transitions: Approaches, Experimental Systems and Models’ brought together an international interdisciplinary team investigators spanning the fields cell developmental biology, stem physics, mathematics engineering to tackle question how cells precisely navigate between distinct identities do so in a dynamic manner. This second edition was organized after successful virtual same topic that took place 2021.
Cellular checkerboard patterns are observed at many stages of embryonic development. We study an analytically tractable model for lateral inhibition and show that the steady states analogous to optical phonons Γ point, which have wave number k=0. cases cells arranged in linear hexagonal lattices. To determine how final pattern is selected it necessary take into account granularity and, analogously solid-state physics, redefine basis lattice sites terms a periodic crystal. The determined by...
Abstract The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching motility powered by retractile extracellular filaments called type IV pili. Single cells twitch successive pili extension, attachment and retraction. However, whether how single control migration remains unclear. We discovered that P. actively directs in the direction of mechanical input from pili, a process we call mechanotaxis. Chp chemotaxis-like system controls balance forward reverse response to...
This work studies the response of migratory machinery in chemotactic cells to a short stimulus with chemo-attractant. In exhibiting noisy oscillations before stimulation, authors observe long transient response, cell returns back its initial oscillatory state. The properties system measured experimentally are well reproduced help model based on generic nonlinear oscillator
Abstract We present a general theory of noisy genetic oscillators with externally regulated production rate. The observables that characterize the oscillator are discussed, and it is shown how their statistics depend on external regulator. show these have generic features observed in two different experimental systems: expression circadian clock genes fibroblasts, transient oscillatory dynamics segmentation cells disassociated from zebrafish embryos. Our work shows oscillations diverse...
En la provincia de Morona Santiago, se utilizó 4%, 8% y 12 % extracto Dulcamara Kalanchoe gastonis bonnieri en el agua bebida pollos broilers línea COBB 500 durante etapa crecimiento engorde con objetivo reducir su morbilidad mortalidad frente a un tratamiento control para costos producción. El diseño investigación fue experimental, cuantitativa, analítica. 100 aves día edad aplicó al azar 4 tratamientos, cada uno ellos 5 repeticiones bajo condiciones controladas; análisis información...