ABSTRACT Objective To compare the effects of loteprednol etobonate (LE) and ketorolac tromethamine (KT) on pupil diameter (PD) aqueous humor levels prostaglandin E 2 (PGE ), total protein (TP), glutathione (GSH) following paracentesis‐induced intraocular inflammation in cats. Methods Thirty cats ( n = 10/group) underwent anterior chamber paracentesis at T1 T2 (60 min apart). At T1, right eye received one drop LE, KT, or saline (CG). PD was measured T2, samples were analyzed for PGE , TP,...

Abstract Objective To determine ultrasonographic and echobiometric findings in the eyes of goats different ages. B A mode ultrasonography was performed 55 healthy Saanen (110 eyes) ages 45 ( n = 15), 180 20), 549 days 20). Procedures Transcorneal after instillation a topical anesthetic application acoustic transmission gel on 20‐MHz linear transducer tip. The placed longitudinal position until optimal scan images, according to echoes were obtained. Statistical analysis carried out compare...

To determine the effects of administration subconjunctival 1% atropine (SA), topical (A), 0.5% tropicamide (T), homatropine (H), 10% phenylephrine (P), and 2% ibopamine (I) on intraocular pressure (IOP), pupil diameter (PD), ruminal motility (RM) intestinal (IM) in sheep.Ten spayed ewes Santa Inês breed.Six experiments were performed separately at 1-week intervals. One eye was randomly selected received one drop A, T, H, P, I, or injection 8 a.m. On following days, IOP PD evaluated every h...

Primary and secondary neoplasia of dogs cats may assume several different forms. Clinical signs are varied, manifest in accordance with the diseased tissue. The present article aims to review clinical pathophysiologic aspects frequent neoplasms that affect by eye adnexal ocular structures cats.

The aim was to determine the intraocular pressure (IOP), ultrasonographic and echobiometric findings in eyes of juvenile Yacare caiman (Caiman yacare).Twenty-two healthy caimans from a breeding farm Brazilian Pantanal.Intraocular measured under physical restraint topical anesthesia by applanation tonometry. Five individual measurements each eye were recorded same examiner. B-mode ultrasonography performed with 10-MHz linear transducer, anterior chamber depth, lens thickness, vitreous axial...

This study aimed to compare the normal intraocular pressure (IOP) and tear secretion, by means of applanation tonometry Schirmer test-1 (STT-1), in goats Saanen breed with different ages, at time points. Thirty six goats, free ocular abnormalities, were grouped into three age categories (n=12), animals 45, 180 549 days age. STT-1 IOP measurements carried out always 9:00am 7:00pm, during consecutive days. Results evaluated statistically (P<0.05). Regarding day, overall values significantly...

Abstract Purpose To study the effects of topical administration 1% morphine on corneal analgesia in rabbits submitted to lamellar keratectomy and assess expression matrix metalloproteinase‐1, metalloproteinase‐2, metalloproteinase‐9 (MMPs), type IV collagen, interleukin‐10 (IL‐10) during treatment. Methods Morphine group (MG) received 50 μL four times daily, while control saline instead. Corneal touch threshold (CTT) wound area were assessed until healing. samples processed for routine...

Tear film disorders in dogs can be classified into quantitative or qualitative abnormalities, both, and are commonly observed daily clinical practice. Inadequate production of one more tear components lead to variable degrees ocular disorders, called keratoconjunctivitis sicca. Keratoconjunctivitis sicca has several causes, but most cases the disease is idiopathic, with T lymphocytes playing a role. In veterinary medicine, diagnosis made based on results Schirmer test. this article, we...

O objetivo do presente estudo foi avaliar retrospectivamente as 20 primeiras ovário-histerectomias vídeo-assistidas com único portal (SPVA-OSH), realizadas por um cirurgião não proficiente nessa técnica. Vinte cadelas foram submetidas à laparoscopia para SPVA-OSH, o auxílio de endoscópio 10mm, canal trabalho 5mm, inserido trocarte, posicionado na região pré-púbica, e coagulação bipolar. tempo cirúrgico médio 22,95±5,17 minutos. Os cinco primeiros procedimentos consumiram mais que os demais....

The knowledge of the normal appearance and ocular dimensions goat eyes facilitates use ultrasonography in evaluation disease. objective present study was to determine ultrasonographic ecobiometric findings adult goats. B- A-mode performed 30 healthy goats (60 eyes) (n=5 intact females n=15 castrated males). Ultrasonography after instillation a topical anesthetic. Lubricating jelly placed on 20MHz transducer tip as stand-off pad. longitudinal position until optimal B-scan images, according...

Abstract Objective To evaluate the effects of agents on corneal re‐epithelization and metalloproteinase‐2 metalloproteinase‐9 ( MMP ‐2 ‐9) activities in corneas rats submitted to ulceration. Animals Studied Ninety eight healthy rats. Procedures Corneal ulcers were created using 1N Na OH their left eye. Eyes treated every 6 h with 1% ethylenediaminetetraacetic acid EDTA ), 3% chondroitin sulfate CS 10% N‐acetylcysteine NA c saline (S) at 6‐h intervals. Corneas stained fluorescein photographed...

Abstract This study aimed to evaluate and correlate intraocular pressure ( IOP ), endothelial cell density CD hexagonality HEX the aqueous humor prostaglandin E 2 PGE ) concentration in dogs with mature MG , n = 8) hypermature HG cataracts. Eight laboratory beagles no ocular abnormalities were included as a control group CG ). The was measured using digital applanation tonometer. Noncontact specular microscopy used . Samples of determine enzyme‐linked immunoassay. Data compared by anova B...

Efficacy of meloxicam, administered by different routes was studied in experimental uveitis dogs. Anterior chamber paracenteses accomplished at two moments (M0 and M1), with a five hour interval among them. At M0 M1, 0.2mL aqueous humor collected total protein prostaglandin E2 (PGE2) quantitation determined. Four groups were formed (n=5), which received meloxicam the end M0. following routes: subcutaneous (GIm), subconjunctival (GII), topical (GIII). A fourth group that no treatment...

A- and B-modes ultrasonographic changes in the thickness of various structures eyeball male female English Cocker Spaniel dogs with without nondiabetic cataracts were evaluated. Sixteen (32 eyes) seven normal (14 older than eight years selected. ultrasonography was performed a 10MHz transducer. Data statistically evaluated by one way ANOVA. Mean standard deviations ocular for were, respectively, anterior chamber: 3.041±0.828mm, 3.373±1.040mm; lens: 6.817±1.117mm, 7.062±0.477mm; vitreous:...

This study aimed to evaluate the effects of tramadol on tear production, intraocular pressure (IOP) and pupil diameter (PD) in healthy dogs. Dogs were randomly assigned receive 4mg kg-1 (n=11) 6mg hydrochloride intramuscularly. Tear production (Schirmer test, STT-1), IOP (applanation tonometry) PD (electronic pachymetry) assessed before, 30 60 minutes after administration tramadol. Data compared by analysis variance for repeated measures (P<0.05). Parameters evaluated at 60min, dogs...

Purposes: To assess the effects of 0.5% ketorolac tromethamine without preservatives on expression iNOS and MMP-9 in alkali burn ulcers. Methods: Twelve eyes 120-day-old male rabbits were treated (TG) every 6 h with 12 other saline solution (CG), immediately after occurrence ulcers by 1 M sodium hydroxide (NaOH). Re-epithelialization was monitored using fluorescein h. After 24 h, six corneas (n=6) each group collected (M1). The others reepithelialization (M2). At both moments, inflammatory...

Abstract Chondrosarcoma accounts for about 10% of all canine bone tumors and is the second most common primary tumor in dogs. In veterinary medicine, chondrosarcomas are classified as skeletal extraskeletal. Extraskeletal mesenchymal neoplasms soft tissues visceral organs that produce neoplastic chondrocytes a fibrillary matrix. There no involvement or periosteal extraskeletal chondrosarcomas. The aim this report to describe first case metastatic intraocular chondrosarcoma dog.

Purposes: To evaluate the effects of nalbuphine 1% on expression metalloproteinase 1 (MMP-1), 9 (MMP-9), and opioid growth factor (OGF) in rabbit corneas after lamellar keratectomy. Methods: The rabbits were assigned to two groups: group (GN, n=30), which received 30 µL 4 daily applications at regular intervals until corneal epithelialization, control (GC, physiological saline solution under same conditions adopted GN. collected for immunohistochemistry days 1, 3, 5, 7, keratectomy,...

O glaucoma mantém-se como uma das principais causas de cegueira em pacientes humanos e entre os animais domésticos. No curso da sua patogênese, ocorre aumento pressão intra-ocular morte células retinianas, cujo início pode ser precoce. Fármacos vêm sendo desenvolvidos visando a se obter o controle proteger as retinianas apoptose morte. presente artigo revisa farmacologia, indicações efeitos adversos substâncias utilizadas topicamente no tratamento do cães, além discutir técnicas cirúrgicas...

ABSTRACT An 8-year-old domestic short hair female cat initially presented with bilateral uveitis pseudotumoral appearance. The patient tested negative for feline immunodeficiency virus (FIV), leukemia (FeLV) and Toxoplasma gondii. Histopathology of a granulomatous lesion on the upper left conjunctiva revealed amastigotes compatible Leishmania spp. Aqueous humor was aspired diagnosis confirmed after isolation promastigotes cultivated in biphasic NNN medium by positive polymerase chain...

This study aimed to determine the effects of different concentrations botulinum toxin type A (BT-A) on semen parameters, and seminal plasma biochemical protein profiles dogs with benign prostatic hyperplasia (BPH). Eighteen sexually intact male BPH were randomly divided in three groups, received an intraprostatic injection saline solution (control group - CG), 250UI (GI) or 500UI (GII) BT-A under transabdominal ultrasound guidance. Semen was collected at baseline, 2, 4 8 weeks after...

Abstract Objectives To investigate the effects of intracameral injection epinephrine and two doses 2% lidocaine on pupil diameter ( PD ), intraocular pressure IOP heart rate HR mean arterial MAP ) in healthy cats. Methods Five treatment groups were formed (10 cats/each). Animals received 0.2 mL epinephrine, or 0.3 lidocaine, BSS . Cats anesthetized, all solutions injected intracamerally. , assessed at baseline, following anterior chamber paracentesis (T0), every 5 minutes, until anesthesia...

The study aimed to evaluate tear production by means of modified Schirmer tes-1 (mSTT-1) in neonate cats. Likewise, correlation between mSTT-1 and STT-1 was assessed vitro. Standard SST strips were cut half after eye lid opening, neonates (n=15) daily measured both eyes (mSTT-1), until the 7th day, at day 14, 21, 28. Animals weighted 28 days age. Results compared statistically (P<0.05). During first 7 days, overall mean 0.76 wetting/minute. Significant differences right left not observed...

The effects of topical levobunolol with the fixed combination 2% dorzolamide-0.5% timolol and association dorzolamide 0.5% on intraocular pressure (IOP), pupil size (PS), heart rate (HR), conjunctival hyperemia in eighteen halthy cats were investigated compared. IOP, PS, HR, conjuntival daily recorded at three times (9a.m., 2p.m., 6p.m.). Three groups formed (n=6), one eye each animal was randomly selected treated (L), or commercial dorzolamide-timolol (DT), (DL). first day (0) consisted...

RESUMO: Objetivou-se identificar microrganismos isolados de diferentes tipos ceratite ulcerativa em cães, juntamente com a sua susceptibilidade antimicrobianos. O resultado do tratamento médico e cirúrgico também foi correlacionado o tipo isolado. Amostras para microbiologia foram obtidas auxílio swab estéril 104 olhos 72 pacientes sem histórico prévio antibióticos tópicos, atendidos no período maio 2012 março 2015. Os testados foram: neomicina, gentamicina, tobramicina, cloranfenicol,...