A5087950211- Parasites and Host Interactions
- Parasitic Diseases Research and Treatment
- Parasite Biology and Host Interactions
- Biosensors and Analytical Detection
- Mosquito-borne diseases and control
- Reproductive Physiology in Livestock
- Rangeland and Wildlife Management
- Veterinary Equine Medical Research
- Child Nutrition and Water Access
- Global Maternal and Child Health
Kenya Medical Research Institute
2019-2024
University of Nairobi
2019
Pennsylvania State University
2006
Lymphatic filariasis is a mosquito borne disease which leads to abnormal painful enlarged body parts, severe disability and social stigma. We screened Wuchereria bancrofti in Matayos constituency Busia County. Blood samples were collected from 23 villages selected purposively based on clinical case reports. Finger prick and/or venous blood sampling collections was carried out. Antigenaemia filarial DNA prevalence determined. Infection rates pools estimated SPSS version 26 used for...
Controlling fertility of feral horses through the use long-acting contraceptives or sterilization approaches has been championed as a reasonable and humane solution for addressing overpopulation problems in several western states. However, methods to accomplish long-term contraceptive efficacy following single treatment have lacking. In fall 2002 spring 2003, we initiated study compare single-shot vaccine directed at gonadotropin releasing hormone (GonaCon™) that zona pellucida (SpayVac)...
Accurate detection of filarial parasites in humans and vectors is essential for the implementation evaluation Global National Programs to eliminate lymphatic filariasis. Immunological methods detect infection are available; however, cross-reactivity issues have been reported most them. Nucleic acid-based molecular assays offer high levels specificity sensitivity can be used infections. In this study, we evaluated loop-mediated isothermal amplification (LAMP) tests amplify Wuchereria...
Schistosomiasis is a neglected tropical disease occurring in sub-Saharan Africa and affecting almost 250 million people. The drug of choice for treatment has been Praziquantel which used many years there need to develop new drugs. immunomodulatory potential Ekebergia capensis extract on both juvenile adult Schistosoma mansoni infection vivo was evaluated this study. Swiss albino mice were infected individually with 90 S. cercariae randomized into groups five each i) plant treated ii)...
INTRODUCTION Lymphatic filariasis and malaria are mosquito-borne diseases co-endemic in coastal Kenya. We evaluated the occurrence of co-infections with Wuchereria bancrofti Plasmodium falciparum, causative agents malaria, respectively, humans known Anopheles vectors from Matayos constituency, Busia County, western MATERIALS AND METHODS The samples were collected purposively based on clinical case reports. Members An. gambiae funestus species complexes present presence W. P. falciparum...
Emerging infections cause considerable public health problems to humanity worldwide. The presence of Biomphalaria spp vector snails, the compatibility snails with schistosomes, and prevalence intestinal schistosomiasis infection in school-going children were determined. study sought determine transmission dynamics Tharaka Nithi, an emerging focus Mt. Kenya highlands. Epidemiological Triangle Model (ETM), which sheds light on infectious diseases, served as foundation for this study. A...
Abstract Lymphatic filariasis is a mosquito borne disease which leads to abnormal painful enlarged body parts, severe disability and social stigma. Early diagnosis interventions are paramount towards achieving the elimination goal. We screened Wuchereria bancrofti in Matayos constituency Busia County. Blood samples were collected from 23 clinical units selected purposively based on case reports. Finger prick and/or venous blood sampling collections was carried out. Antigenaemia filarial DNA...
Abstract Introduction Lymphatic filariasis is a debilitating disease caused by filarial worms; Wuchereria bancrofti, Brugia Malayi and B. Timori . It earmarked for elimination the year 2020 through Global Program Elimination of Filariasis (GPELF). In Kenya, mass treatment has been ongoing since 2002 though it not consistent as recommended World health organization (WHO). Taking this into account, emergence W. bancrofti resistance strains against current choice drugs cannot be ruled out....