(1) Background: The challenges in Implantology involve the development of alternative methods to enhance bone repair patients with systemic conditions, such as osteoporosis. This study aimed evaluate effect a local anti-sclerostin monoclonal antibody (Scl-Ab) on functionalization titanium implant surfaces through dip-coating technique peri-implant repair. (2) Methods: A total 32 female rats were separated into four groups (n = 8): SHAM NT (Sham surgery), OVX (ovariectomy), Scl-Ab (SHAM;...

The hypothesis of this study was that the peri-implant bone healing group pinealectomized rats would differ from control group. samples were subjected to immunohistochemical, microtomographic (total porosity and connectivity density), fluorochrome (mineralized surface) analyses. Objectives goal investigate cellular changes remodeling dynamics along bone/implant interface in rats. Material Methods total 18 adult male (Rattus norvegicus albinus, Wistar) divided into three groups (n=6): (CO),...

OBJECTIVE: This study proposes to evaluate, by means of microtomographic analysis, the topical potential raloxifene combined with BioGran® through sonochemical method in repair critical bone defects calvaria rats. The hypothesis was that homogenization Raloxifene Biogran at 20% concentration would improve grafted site.MATERIALS AND METHODS: A 5-mm defect induced three groups: CTR (100% BioGran®); RAL10 (90% and 10% raloxifene), RAL20 (80% raloxifene). animals were euthanized after 30 days...

The aim of this study was to analyze the stages alveolar bone repair in type 2 diabetic rats evaluating mechanism mineralization and remodeling processes after dental extraction. Forty-eight were divided into normoglycemic (NG) diabetes (T2D) groups. upper right incisor extracted 3, 7, 14 42 days animals euthanized. following analyses performed: immunolabeling against antibodies TNFα, TGFβ, IL6, WNT, OCN TRAP, collagen fibers maturation, microtomography confocal microscopy. Data submitted...

Objective: The aim of this study was to evaluate the osteoconductive potential BoneCeramic™ on bone healing in rat calvaria 5-mm defects. Material and Methods: A defect induced three groups not filled with biomaterial [Clot Group (CG)], autogenous (AG), or Bone Ceramic (BCG). Animals were euthanized after 14 28 days tissue within central area evaluated. Results compared using ANOVA Tukey test (p<0.05). Immunohistochemistry performed primary antibodies against osteocalcin, RUNX-2, TRAP, VEGF...

Dentigerous cysts are defined as a cyst originated by separation of the follicle dental crown tooth unerupted. Although most dentigerous considered developmental cysts, some cases seem to have an inflammatory origin. The aim this study was show case 8-year-old patient, male, presenting lesion in maxilla with large proportions. Computed tomography scans showed hypodense image, well-defined, associated unerupted teeth. treated enucleation under local anesthesia. Histopathological examination...

The success of biomaterials for bone regeneration relies on many factors, among which osseointegration plays a key role. Biogran (BG) is bioactive glass commonly employed as graft in dental procedures. Despite its use clinical practice, the capability BG to promote has never been resolved at nanoscale. In this paper, we present workflow characterizing interface between newly formed and preclinical rat model. Areas bone–BG contact were first identified by backscattered electron imaging...

(1) Background: There are many therapies for osteoporosis control and bone maintenance; anabolic drugs such as teriparatide grafts help in the repair process stimulate formation. Thus, aim of present study was to evaluate behavior repaired presence PTH (teriparatide) associated with Biogran® (biomaterial) through a sonochemical procedure after extraction rats. (2) Methods: The insertion alveolus performed 30 days incisor extraction. Euthanasia occurred 60 days. (3) Results: use local...

The excessive unilateral tearing as a result of gustatory stimuli is characteristic crocodile tears syndromes. aim this study to report 2 cases Frey and syndromes, considering diagnosis, monitoring, selection appropriate treatment. A 74-year-old female patient presented with history Bell palsy, on left eye at the moment chewing, absence pain. opted only for periodic case monitoring because symptoms by syndrome did not bother her, which made any invasive procedure unnecessary, closed...

Central cemento-ossifying fibroma is characterized by the combined production of osteoid and cementoid tissue. Radiographically, this lesion presented as an outlined cortical variable radiopaque spots, also can be present complete radiolucent or different degrees radiopacity. The recommended treatment curettage enucleation, recurrence rate less than 5%. Considering that surgical invasive, mainly in large lesions, study aims to report a patient whom conservative was carried out involving...

Craniofacial trauma can lead to several complications. The combined fractures of anterior and posterior walls the frontal bone are almost always followed by lesions in nasofrontal orifices disruption ostia or ducts, a significant factor for development early late complications after sinus fractures. This article reports case patient, who underwent neurological evaluation at first showed good general condition. Computed tomography noted fracture small foci pneumocephalus cerebral cortex....

(1) Background: The objective of this study was to evaluate the morphometry peri-implant bone tissue in orchiectomized rats, treated with vitamin D isolated or associated teriparatide. (2) Methods: 24 rats were divided into 4 groups: ORQ-orchiectomy, without drug treatment, ORQ+D-orchiectomy, D, ORQTERI-orchiectomy, teriparatide and ORQTERI+D-orchiectomy, + D. Each animal received an implant tibial metaphysis. Euthanasia occurred 60 days after surgery. Computed microtomography (micro-CT)...

Background . Complex dental infections can reach distant areas of the alveolar process, invading secondary fascial spaces. Objectives This case report aims to show a misdiagnosis odontogenic infection and great need for dentist in hospital environment. Case Report A male patient presented facial asymmetry trismus, while CT examination showed hyperdense mass involving left masseteric, pterygomandibular, superficial temporal regions. The was then referred oral oncology center by emergency...

Necrotizing fasciitis (NF) is a devastating disease that typically affects immunocompromised patients, chronically debilitated patients or drug users, but can also affect healthy patients. rapidly produce septic shock and requires immediate surgical management of the necrotic tissue. It bacterial infection progresses has high mortality generally caused by aerobic anaerobic bacteria. The patient was user. During treatment, combination broad-spectrum antibiotic therapy with Ciprofloxacin...

Estrogen deficiency is one of several contributing factors to catabolic changes in bone surrounding dental implants, impairing repair defects requiring regeneration. Functionalizing substitutes an alternative approach among various strategies address this challenge. In study, the aim was evaluate effect functionalizing deproteinized bovine (Bio-Oss

to evaluate the morphological and functional characteristics of peri-implant bone tissue that was formed during healing process by placement implants using two different surface treatments: hydrophilic Acqua™ (ACQ) rough NeoPoros™ (NEO), in spontaneously hypertensive (SHR) normotensive rats (Wistar) whether or not treated with losartan.

Gomes-Ferreira, Pedro Henrique Silva DDS; de Carvalho Reis, Erik Neiva Ribeiro Faverani, Leonardo Perez DDS, PhD; Oliveira, Danila; Carrasco, Leandro Carlos Vieira, Jefferson Moura DDS Author Information