A5086081334- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Bone health and treatments
- Periodontal Regeneration and Treatments
- Bone health and osteoporosis research
- Bone Metabolism and Diseases
- Orthopaedic implants and arthroplasty
- Bone and Dental Protein Studies
- Dental Radiography and Imaging
- Facial Trauma and Fracture Management
- Oral and Maxillofacial Pathology
- Endodontics and Root Canal Treatments
- dental development and anomalies
- Cleft Lip and Palate Research
- Bone fractures and treatments
- Dental Trauma and Treatments
- Laser Applications in Dentistry and Medicine
- Orthodontics and Dentofacial Orthopedics
- Bone and Joint Diseases
- Dental materials and restorations
- Craniofacial Disorders and Treatments
- Oral and gingival health research
- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Surgical Oncology
- Temporomandibular Joint Disorders
Universidade Estadual Paulista (Unesp)
2016-2025
Okinawa Prefectural Chubu Hospital
2025
Centro Universitario Toledo
2015-2021
Universidade de São Paulo
2002-2019
National Council for Scientific and Technological Development
2016
Centro Universitário de Araraquara
2016
Fundação Faculdade de Odontologia
2010-2015
Universidade de Ribeirão Preto
2014
Universidade Sagrado Coração
2011-2013
Osaka Medical Center for Cancer and Cardiovascular Diseases
2008
Abstract Objectives: In this in vivo animal study, we evaluated the effect of plasma electrolytic oxidation (PEO) coating on topographic and biological parameters implants installed rats with induced osteoporosis low-quality bones. Materials methods: total 44 Wistar ( Rattus novergicus ), 6 months old, were submitted to ovariectomy (OXV group) dummy surgery (SHAM group). After 90 days, ELISA test was performed effectiveness confirmed. each tibial metaphysis, an implant PEO containing Ca 2+ P...
Abstract Aim: To describe the early healing within void obtained after elevation of sinus mucosa and simultaneous implant installation without use any grafting material in monkeys. Material methods: Implants were installed simultaneously with maxillary using lateral approach eight monkeys material. The 4, 10, 20 30 days was evaluated area distal to implants. Paraffin sections prepared analyzed qualitative histological methods. Results: process initiated by formation a coagulum followed...
Alveolar bone healing after upper incisor extraction in rats is a classical model of preclinical studies. The underlying morphometric, cellular and molecular mechanism, however, remains imprecise unique study.The aim this study was therefore to characterize the alveolar by micro computed tomographic (Micro-CT), immunohistochemical real-time polymerase chain reaction (RT-PCR) analysis.Thirty animals (Rattus norvegicus, Albinus Wistar) were divided into three groups incisors at 7, 14, 28 days....
DNA-based biomaterials have been proposed for tissue engineering approaches due to their predictable assembly into complex morphologies and ease of functionalization. For bone regeneration, the ability bind Ca2+ promote hydroxyapatite (HAP) growth along DNA backbone combined with degradation release extracellular phosphate, a known promoter osteogenic differentiation, make unlike other currently used materials. However, use as biodegradable scaffolds repair remains scarce. Here, we describe...
Little information is available on the molecular events that occur during graft incorporation over time. The calvarial bone (Cb) grafts have been reported to produce greater responses compared with other donor regions in maxillofacial reconstructions, but scientific evidences for this are still lacking. objectives of study (1) morphological pattern Cb onlay and compare them biological through immunohistochemical (2) establish effects perforations maintaining volume density receptor bed.Sixty...
Abstract Type 2 diabetes interferes with bone remodeling mechanisms, requiring studies to reverse this damage, and resveratrol is a polyphenol rich properties. This study aimed characterize the long morphology peri-implant biomechanics of normoglycemic type diabetic animals treated resveratrol. Thirty-two male Wistar rats were used divided into or without treatment. They had installation implants in tibia treatment oral within 45 days. Resveratrol was responsible for weight homeostasis...
Hypertension is a global health concern not only correlated with cardiovascular complications, but also impaired bone metabolism, potentially affecting healing at the bone–implant interface. Losartan, an angiotensin II receptor blocker (ARB) commonly prescribed for hypertension, has shown beneficial effects on in spontaneously hypertensive rats (SHRs). However, influence of hypertension and ARBs like losartan cellular response interface remains underexplored. Methods: A total 32 were...
Abstract Objective Titanium surface modifications improve osseointegration in dental and orthopedic implants. However, soft tissue cells can also reach the implant immediate loading protocols. While previous research focused on osteogenic cells, early response of still needs to be better understood. Material methods We have established a bioassay this aim where human gingival fibroblasts, HSC2 oral squamous carcinoma murine bone marrow were cultured onto titanium discs or exposed respective...
This study evaluated the clinical and tomographic outcomes of socket healing. Immediate implants were placed in molar area, gap was filled with either deproteinized bovine bone mineral (B) or collagen matrix (BM), n = 14/group. Scores epithelization healing, immunoassay for VEGF, IL-1β, FGF from wound exudate, keratinized mucosa variation (ΔKM), levels evaluated. The B group had slower tissue maturation than BM (p < 0.05), but gingival epithelialization similar > 0.05). At restorative...
Estrogen deficiency contributes to osteoporosis and can therefore compromise the peri-implant bone. Hence, this study evaluated bone healing when Rubus coreanus (RC) was administered orally in ovariectomized healthy rats. Forty 4-month-old female rats were divided into four groups: SHAM (healthy rats), SHAM/RC treated with RC), OVX (ovariectomized OVX/RC RC). The oral administration of RC started thirty days after ovariectomy, implant placement rat tibia occurred ninety ovariectomy....
Estrogen deficiency, coupled with a cafeteria diet (CD), can impair peri-implant bone repair, posing significant challenge to implant success in affected individuals. Thus, it is crucial explore strategies for functionalization and systemic treatments that could alleviate these alterations. This study aimed assess repair ovariectomized (OVX) rats subjected CD, focus on implants functionalized genistein (GEN), compared conventional (CONV), the effects of treatment risedronate sodium (RIS). In...
Bone substitutes are commonly used in bone regeneration, and their functionalization with bioactive molecules can significantly enhance regeneration by directly influencing cells. This study aimed to evaluate the potential of raloxifene-functionalized Cerabone® (CB) for promoting repair highlight implications regeneration. The effectiveness functionalized raloxifene via sonication or gel delivery rat calvaria defects was assessed. Ninety-six male rats critical-sized calvarial were divided...
After surgical tooth extraction, it is necessary to maintain the environment of oral cavity in appropriate conditions favor alveolar bone repair. Coffee includes multiple bioactive compounds; some these compounds can affect metabolism. The aim this study was investigate effect coffee ingestion on dynamics after extraction using confocal laser microscopy. Eight male Wistar rats, aged two months, were used and divided into groups: control group, which normal diet maintained, experimental with...
Synthetic bone substitutes based on hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) are widely used in regenerative dentistry due to their favorable biocompatibility osteoconductive properties. This study aimed evaluate, through laboratory-based analyses, the porosity surface characteristics of Nanosynt Block (FGM Dental Group®) for regeneration applications. The Block, consisting 60% HA 40% β-TCP, was analyzed using scanning electron microscopy (SEM) morphology characterization,...