Gökhan Kasnak

ORCID: 0000-0002-8953-6834
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Oral and gingival health research
  • Periodontal Regeneration and Treatments
  • Dental Implant Techniques and Outcomes
  • Laser Applications in Dentistry and Medicine
  • Dermatoglyphics and Human Traits
  • Dermatologic Treatments and Research
  • Surgical Sutures and Adhesives
  • Venous Thromboembolism Diagnosis and Management
  • Protease and Inhibitor Mechanisms
  • Antimicrobial Peptides and Activities
  • Oral and Maxillofacial Pathology
  • NF-κB Signaling Pathways
  • HIV/AIDS oral health manifestations
  • Cutaneous Melanoma Detection and Management
  • Adenosine and Purinergic Signaling
  • Aldose Reductase and Taurine
  • Dental Health and Care Utilization
  • dental development and anomalies
  • Curcumin's Biomedical Applications
  • Melanoma and MAPK Pathways
  • Orthopedic Surgery and Rehabilitation
  • Dental Education, Practice, Research
  • Drug-Induced Adverse Reactions
  • Immune Response and Inflammation

Istanbul Kent University
2021-2024

Istanbul University-Cerrahpaşa
2021

Istanbul University
2018-2021

Istanbul Aydın University
2019

University of Turku
2018

Reactive oxygen species contribute to periodontal tissue homeostasis under control of anti-oxidative responses. Disruption in this balance induces severe inflammation and extended degradation.Aim study was identify the expression levels nuclear factor, erythroid 2 like (NFE2L2/NRF2), Parkinsonism associated deglycase (PARK7/DJ-1), kelch-like ECH protein 1 (KEAP1), 8-hydroxy-deoxyguanosine (8-OHdG) peri-implant mucosal tissues affected by peri-implantitis, compare those periodontally diseased...

10.1111/cid.12619 article EN Clinical Implant Dentistry and Related Research 2018-05-22

Chymotrypsin-like-proteinase of Treponema denticola (Td-CTLP) can stimulate the protein expression and activation matrix metalloproteinase (MMP)-8 (or collagenase-2), a potent tissue destructive enzyme from gingival cells in vitro. The aims this study were 1) to demonstrate proMMP-8 latent MMP-8) by Td-CTLP vitro 2) detect MMP-8 levels samples peri-implantitis periodontitis patients.proMMP-8 was analyzed immunoblots. Tissue specimens collected 38 systemically healthy non-smoking patients; 14...

10.1016/j.acthis.2021.151767 article EN cc-by Acta Histochemica 2021-08-19

Background A possible link between periodontal pathogenic bacteria and atherosclerosis may exist based on the inflammatory mechanisms initiated by found in lesions. Our aim was to investigate presence of DNA originating from T. denticola, C. rectus, forsythia, P. gingivalis vascular tissue specimens obtained patients who underwent surgery for arteriosclerotic disease this study. Methods total 96 diagnosed with valvular heart due 85 advanced aortic valve stenosis rheumatic fever had undergone...

10.7754/clin.lab.2020.191146 article EN Clinical Laboratory 2020-01-01

Complications after free gingival graft (FGG) operations are generally related to the donor site. The titanium-prepared, platelet-rich fibrin (T-PRF) placement in site accelerate wound healing and prevent postoperative complications such as pain hemorrhage. We aim evaluate effect of T-PRF regarding vascularization tissue thickness report advantages ultrasonography (US) FGG.Ten individuals were divided into two groups control. While membrane was placed at group, a gelatin sponge control...

10.1002/jper.21-0076 article EN Journal of Periodontology 2021-06-01

Abstract Objective Various suture materials and needles are now available for use in the dental surgery. The aim of this study was to determine preference among Turkish dentists by a survey. Materials Methods survey prepared sent electronically through e-mail and/or Facebook. Dentists were asked report their graduation year from school specialty if they have one. In addition, type periodontal/implant operations frequency those applied them questioned. participants indicate preferences these...

10.1055/s-0039-1688732 article EN cc-by-nc-nd European Journal of Dentistry 2019-02-01

The progression of periodontitis depends on the changes in bone and connective tissue homeostasis imbalance biofilm host immunoinflammatory response, particularly matrix metalloproteinases (MMP).To assess probable relation between subgingival anaerobic flora expression MMP-3 patients with generalized aggressive (AgP), chronic (CP) healthy subjects, to evaluate these levels according varied loss severity.The plaque index (PI), gingival (GI), probing depth (PD) clinical attachment (CAL) were...

10.5114/ceji.2019.92806 article EN Central European Journal of Immunology 2019-01-01

The purposes of this study were to localize monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) and its suppressor mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT-1) in gingival tissues profile their expression levels relation the clinical inflammation, Porphyromonas gingivalis colonization, interleukin (IL)-8 levels.Study samples collected from two independent populations: (1) Gingival eight periodontally healthy individuals periodontitis patients MCPIP-1...

10.1007/s00784-023-05010-5 article EN cc-by Clinical Oral Investigations 2023-04-03

Periodontitis is characterized by the destruction of tooth-supporting tissues. Matrix metalloproteinases (MMPs) play a significant part in degradation collagen structure. The gingival crevicular fluid (GCF) levels MMPs increase with progression periodontal inflammation. Polymorphisms can be responsible for high expression and exacerbate breakdown This study aims to investigate effect MMP-3 -1171 5A/6A polymorphism GCF group Turkish periodontitis patients.Non-smoking, stage II grade A (S...

10.3390/pathogens10101260 article EN cc-by Pathogens 2021-09-29

Background/Aim: Type 2 diabetes mellitus (T2DM) and periodontitis are both characterized as chronic inflammatory disorders that have a mutually influential association. Dysregulation of glucose levels in individuals with T2DM has significant impact on the pathophysiology equilibrium mediators. Multiple mediators produced throughout cascade T2DM, including matrix metalloproteinases (MMPs). Objective this study was to determine if MMP-3, -8, -9 attributed grade III patients uncontrolled T2DM....

10.5937/bjdm2403185k article EN cc-by Balkan Journal of Dental Medicine 2024-01-01

Purpose: The goal of this study is to compare the scalpel and diode laser methods for treating gingival hyperpigmentation in terms postoperative discomfort wound healing. Materials & Methods: Sixteen systemically healthy individuals diagnosed with light or moderate were enrolled study. Patients randomly assigned one two treatment groups: laser. Dummett’s oral pigmentation index was recorded at baseline. Early healing post-operative evaluated on 7th day by using VAS form. Comparisons...

10.52037/eads.2021.0030 article EN cc-by-nc European Annals of Dental Sciences 2021-12-28

Abstract Helicobacter cinaedi (H. cinaedi) is a Gram-negative curved motile rod that causes bloodstream or enteric infections. It was suggested H. involved in the progression of atherosclerosis. We aimed to investigate presence DNA using nested-polymerase chain reaction (PCR) atheroma plaques from patients with atherosclerosis-induced vascular diseases. A total 129 diagnosed valvular heart disease due atherosclerosis and 146 non-atherosclerotic post-stenotic dilatation were included as...

10.2478/ahem-2021-0003 article EN Postępy Higieny i Medycyny Doświadczalnej 2021-01-01
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