A5030107910- Cervical Cancer and HPV Research
- Genital Health and Disease
- Head and Neck Cancer Studies
- Oral Health Pathology and Treatment
- Hepatitis B Virus Studies
- Molecular Biology Techniques and Applications
- Cancer-related Molecular Pathways
- Reproductive tract infections research
- Oral and Maxillofacial Pathology
- Urological Disorders and Treatments
- Cancer-related molecular mechanisms research
- Endometrial and Cervical Cancer Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Viral-associated cancers and disorders
- Herpesvirus Infections and Treatments
- Salivary Gland Disorders and Functions
- HIV/AIDS oral health manifestations
- Oral microbiology and periodontitis research
- Virus-based gene therapy research
- Head and Neck Surgical Oncology
- RNA Interference and Gene Delivery
- Reproductive System and Pregnancy
- Cleft Lip and Palate Research
- Colorectal and Anal Carcinomas
- Esophageal Cancer Research and Treatment
University of Turku
2016-2025
Turku University Hospital
2016-2025
University of Helsinki
1983-2022
Helsinki University Hospital
1991-2022
Biocenter Finland
2016-2017
Hospital de Câncer de Barretos
2014
Universitätsklinik für Frauenheilkunde und Geburtshilfe
2012
Medical University of Graz
2012
Universidade Estadual de Campinas (UNICAMP)
2005-2010
University of Bologna
2007-2010
ABSTRACT In contrast to cervical cancer, integration of human papillomavirus (HPV) DNA into the host genome has been considered a rare event in cancer precursor lesions (cervical intraepithelial neoplasia [CIN]). With our new real-time PCR method, we demonstrated that integrated HPV type 16 (HPV16) is already present CIN lesions. The physical state HPV16 and viral load were simultaneously detected. A unique region E2 open reading frame (ORF) most often deleted during targeted by one set...
ABSTRACT The Finnish HPV Family Study is a prospective cohort study assessing the dynamics of human papillomavirus (HPV) transmission between parents and infant. Serial genital oral scrapings from 76 families, including mother, father, infant, semen samples were collected over 2 years follow-up, analyzed by nested PCR, confirmed hybridization with 12 high-risk (HR) types. most common profile was HR in all family members (29%), followed HPV-positive mother-infant pairs (26%). father-infant...
Objectives: To assess the performance indicators of visual inspection with acetic acid (VIA) and Lugol's iodine (VILI) in four Latin American centres participating ongoing AMerican Screening (LAMS) study, settings moderate incidence cervical disease poorly to moderately well-organized cancer screening. Setting: Three Brazilian (São Paulo, Campinas Porto Alegre) one Argentine centre (Buenos Aires) recruited a total 11,834 healthy women undergo VIA, VILI, conventional Pap smear Hybrid Capture...
Prevalence of genital human papillomavirus (HPV) infection in the general population is not known. No one test alone can detect all HPV infections.To determine prevalence and risk factors for infections healthy males. Voluntary Finnish Army conscripts were examined using peniscopy, cytology (PAP smear) polymerase chain reaction (PCR) brush samples.A total 1,471 (99.6%) males completed questionnaire soliciting their sexual habits, 432 them enrolled clinical study.The study group differed from...
Background. This study is aimed to clarify data on the acquisition, persistence, and clearance of high-risk types human papillomavirus (HPV) DNA from mucosa determinants persistent mucosal HPV infection in infants. Methods. Oral genital scrapings 324 infants were collected at birth, 3 days after delivery, 1, 2, 6, 12, 24, 36 months delivery tested for presence by nested polymerase chain reaction hybridization with 12 oligoprobes. status demographic parents analyzed. Results. During follow-up...
Abstract A series of 51 biopsies derived from the same number patients with established invasive squamous‐cell carcinoma esophagus in Linxian, a high‐risk area for esophageal cancer China, were analyzed histologically and by situ DNA hybridization to demonstrate human papillomavirus (HPV) infection. Epithelial changes suggesting HPV infection within or adjacent lesions found 25 cases (49.0%). Esophageal morphology showed both flat (25 cases) inverted condylomas (2 resembling those genital...
The effects of seminal high-risk human papillomavirus (HPV) DNA were assessed on the quality semen. Semen samples 65 men participating in ongoing Finnish HPV Family Study collected. analyses done by guidelines Nordic Association for Andrology. was detected nested polymerase chain reaction and confirmed Southern blot hybridization types. Altogether, 10/65 (15.4%) had positive semen sample. Seminal did not affect volume, sperm concentration, motility vitality spermatozoa. However, pH...