A5012890854- Pneumocystis jirovecii pneumonia detection and treatment
- Parasitic Diseases Research and Treatment
- Parasite Biology and Host Interactions
- Tuberculosis Research and Epidemiology
- Parasitic Infections and Diagnostics
- Insects and Parasite Interactions
- Parasitic infections in humans and animals
- Pneumonia and Respiratory Infections
- Helminth infection and control
- Veterinary medicine and infectious diseases
- HIV/AIDS drug development and treatment
- Toxoplasma gondii Research Studies
- Herpesvirus Infections and Treatments
- Mycobacterium research and diagnosis
- Antimicrobial Resistance in Staphylococcus
- Reproductive Biology and Fertility
- Zoonotic diseases and public health
- Infectious Diseases and Mycology
- Sperm and Testicular Function
- Diphtheria, Corynebacterium, and Tetanus
- Veterinary Equine Medical Research
- Rabies epidemiology and control
- Orthopaedic implants and arthroplasty
- Parasites and Host Interactions
- Probiotics and Fermented Foods
University of Helsinki
2015-2024
Finnish Meteorological Institute
2022
Finnish Institute for Health and Welfare
2022
Helsinki University Hospital
1996-2022
Daugavpils University
2013
Institute of Food Safety, Animal Health and Environment “BIOR”
2013
Clinical Emergency Hospital Bucharest
2012
University of Opole
2008
University of Veterinary Medicine
2000
University of California, Davis
1998
ABSTRACT It is known that virtually all healthy adult dogs and cats harbor spiral helicobacters in their gastric mucosa. Three species, Helicobacter felis , bizzozeronii salomonis have been isolated vitro from the mucosa of these animals. The aims this study were to evaluate efficacy an isolation method for canine feline has developed at University Helsinki; estimate prevalence distribution taxa samples examined; assess validity extensive set standardized conventional phenotypic tests,...
Contents Transplantation of testicular cells, also known as spermatogonial stem cell transplantation, is a relatively new approach in the field male infertility. We used this technique to determine whether donor‐derived sperm production unrelated porcine recipients possible following ultrasound‐guided transfer cells. This study was undertaken because we had strain Finnish Yorkshire boars with hereditary recessive gene defect rendering all spermatozoa immotile and anatomically abnormal...
In Staphylococcus aureus, ClpP proteases were previously shown to be essential for virulence and stress tolerance in strains derived from NCTC8325. Because these exhibit a severely reduced activity of the alternative sigma factor, SigB, we here reassessed role SigB-proficient clinical strains. To this end, clpP was deleted COL, Newman, SA564, characterized phenotypically. The proteomic changes accomplished by deletion different analyzed using 2-D DIGE technique. analyses revealed mostly...
Inherited ataxias are characterized by degeneration of the cerebellar structures, which results in progressive motor incoordination. Hereditary occur many species, including humans and dogs. Several mutations have been found humans, but genetic background has remained elusive The Finnish Hound suffers from an early-onset ataxia. We performed clinical, pathological, studies to describe disease phenotype identify its cause. Neurological examinations on ten affected dogs revealed rapidly...
Three subgroups of the Finnish cat population underwent investigation for different aspects feline toxoplasmosis. Blood samples 445 purebred pet cats and 45 shelter were screened Toxoplasma gondii–specific immunoglobulin G antibodies with a direct agglutination test. The overall seroprevalence was 48.4%; older receiving raw meat in their diet more often seropositive. Fecal obtained from 131 shelters cats; 2 found shedding T. gondii–like oocysts, oocysts shed by 1 confirmed as gondii...
Abstract Distinctive colour patterns in dogs are an integral component of canine diversity. Colour pattern differences thought to have arisen from mutation and artificial selection during after domestication wolves but important gaps remain understanding how these evolved genetically controlled. In other mammals, variation at the ASIP gene controls both temporal spatial distribution yellow black pigments. Here, we identify independent regulatory modules for ventral hair cycle expression,...
Abstract Pneumocystis jirovecii , the fungal agent of human pneumonia, is closely related to macaque . Little known about other species in distantly mammals, none which are capable establishing infection humans. The molecular basis host specificity remains unknown as experiments limited due an inability culture any vitro. To explore evolutionary adaptations, we have sequenced genomes infecting macaques, rabbits, dogs and rats compared them available humans, mice rats. Complete whole genome...
Examination of 627 wild animals--raccoon dogs (Nyctereutes procyonoides), red foxes (Vulpes vulpes), European lynxes (Lynx lynx), brown bears (Ursus arctos), wolves (Canis lupus), and badgers (Meles meles)--revealed Trichinella spp. The prevalence varied according to geographical region Finland (north; southwest, SW; southeast, SE) was the highest among (70%, SW). risk trichinellosis higher in SE (odds ratio, OR, 19.4) SW regions (OR 14.3), as compared with northern 1), no difference between...
To investigate the role of complement cascade induced damage and protection against it in acute arthritides compared to rheumatoid arthritis other chronic joint derangements. C3c, C9, protectin (CD59) were examined by avidin-biotin-peroxidase complex staining. Marked deposits C3c C9 found synovial vasculature intercellular matrix lining (including bacterial, reactive, osteoarthritis flare up). Furthermore, was not visible cells relatively weakly expressed stromal endothelial arthritis; also...
Eighty-five male Han-Wistar rats were arranged into three groups: CCl4-exposed rats, CCl4 + betaine-exposed and control rats. To see the effect of betaine alone, five groups sacrificed after 7 days, before exposure to CCl4. After that, two (the groups) exposed (1 ml/kg per day subcutaneously [SC] for 4 consecutive days), one (control group) was given olive oil SC days). At start study (day 0), 1, 2, 3, 4, 3 days last injections 7), samples group sacrificed, livers taken chemical analyses...
ABSTRACT Unidentified lactic acid bacterium (LAB) isolates which had mainly been detected in spoiled, marinated, modified atmosphere packaged (MAP) broiler meat products during two previous studies, were identified and analyzed for their phenotypic properties the capability to produce biogenic amines. To establish taxonomic position of these isolates, 16S rRNA gene sequence analysis, numerical analysis ribopatterns, DNA-DNA hybridization experiments done. Unexpectedly a...
We report an unusual case of human babesiosis in Finland a 53-year-old man with no history splenectomy. He had rudimentary spleen, coexisting Lyme borreliosis, exceptional dark streaks on his extremities, and subsequent disseminated aspergillosis. was infected Babesia divergens, which usually causes bovine Finland.
Although human infections caused by Trichinella sp. have not been reported in Finland for several decades and infection pork has become virtually extinct the last decade, sylvatic spp. is still highly prevalent Finland. Muscle digestion of 2,483 carnivorous wild animals from 9 host species during 1999-2005 showed 617 positive (24.8%). Molecular identification 328 larval isolates revealed 4 different endemic species, i.e., T. nativa, spiralis, britovi, pseudospiralis. Seven percent infected...
Abstract Background Dilated cardiomyopathy (DCM) is a life-threatening heart disease and common cause of failure due to systolic dysfunction subsequent left or biventricular dilatation. A significant number cases have genetic etiology; however, as complex disease, the exact risk factors are largely unknown, many patients remain without molecular diagnosis. Methods We performed GWAS followed by whole-genome, transcriptome, immunohistochemical analyses in spontaneously occurring canine model...
Isolates 302, 334, 356, 377 and 379, detected in modified-atmosphere-packaged broiler meat, together with strains LMG 12317 T 13617, dog tonsils, were analysed a polyphasic taxonomy study, including numerical analysis of ribopatterns whole-cell protein patterns, 16S rRNA gene sequence analysis, DNA–DNA hybridization determination some phenotypic properties. The results indicated that these isolates represent novel species the genus Enterococcus . showed classical reactions for exception not...
SUMMARY The first reported bovine botulism outbreak in Finland is described. Nine out of 90 cattle on a dairy farm died after being fed non-acidified silage contaminated by animal carcasses. Type C botulinum neurotoxin gene was detected one heifer polymerase chain reaction (PCR) and the mouse bioassay. Clostridium type isolated from liver samples. strain identified with amplified fragment length polymorphism (AFLP) analysis as group III C. . To our knowledge, this time that has been...
Cestodes of the genus Taenia are parasites mammals, with mainly carnivores as definitive and herbivores intermediate hosts. Various medium-sized cats, Lynx spp., involved in life cycles several species Taenia. The aim present study was to identify tapeworms Eurasian lynx (Lynx lynx) from Finland. In total, 135 72 were subjected molecular identification based on sequences 2 mtDNA regions, cytochrome c oxidase subunit 1 NADH dehydrogenase genes. Available morphological characters rostellar...