A5052562833- Scheduling and Optimization Algorithms
- Optimization and Search Problems
- Ionic liquids properties and applications
- Ferroelectric and Piezoelectric Materials
- Adsorption and biosorption for pollutant removal
- Analytical chemistry methods development
- Advanced Manufacturing and Logistics Optimization
- Extraction and Separation Processes
- Optimization and Packing Problems
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Acoustic Wave Resonator Technologies
- Microwave Dielectric Ceramics Synthesis
- Seismic Performance and Analysis
- Masonry and Concrete Structural Analysis
- Assembly Line Balancing Optimization
- Data Management and Algorithms
- Facility Location and Emergency Management
- Cardiac Ischemia and Reperfusion
- Circular RNAs in diseases
- RNA regulation and disease
- Advanced Clustering Algorithms Research
- Pesticide Residue Analysis and Safety
- Metabolomics and Mass Spectrometry Studies
- Nanomaterials for catalytic reactions
China Agricultural University
2021-2024
Hefei University
2023-2024
Zhejiang University of Technology
2023
Southwest Jiaotong University
2019-2023
Purdue University West Lafayette
2023
Jiaxing University
2023
Linyi University
2007-2022
Jining First People's Hospital
2021
Linyi People's Hospital
2014-2020
Qufu Normal University
2009
Background: Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. Currently, best treatment options for myocardial infarction focus on restoration blood flow as soon possible, which include reperfusion therapy, percutaneous coronary intervention, and therapeutic thrombolytic drugs. Materials methods: In present study, we report development lipid-polymeric nanocarriers (LPNs) mitochondria-targeted delivery tanshinone IIA (TN). D-α-tocopheryl polyethylene glycol 1000...
Vascular calcification is highly prevalent in patients with type 2 diabetes mellitus (T2DM), one of the most common chronic diseases high morbidity and mortality. In recent years, microRNAs have been widely reported as potential biomarkers for diagnosis treatment T2DM. We hypothesized that miR-128-3p associated cardiovascular insulin resistance (IR) rats T2DM by targeting ISL1 via Wnt pathway. Microarray analysis was adopted to identify differentially expressed genes related models were...
Abstract Myocardial infarction (MI) is an acute coronary syndrome that refers to tissue of the myocardium. This study aimed investigate effect long intergenic non‐protein‐coding RNA (lincRNA) ATPase plasma membrane Ca 2+ transporting 1 antisense (ATP2B1‐AS1) against MI by targeting nuclear factor‐kappa‐B inhibitor alpha (NFKBIA) and mediating (NF‐κB) signalling pathway. An mouse model was established idenepsied cardiac function evaluation. It determined ATP2B1‐AS1 highly expressed, while...
Enhancing the dissolution of lipophilic agrochemicals is paramount for addressing agricultural environmental pollution and improving utilization efficiency. This study introduced a novel methodology to enhance pesticide solubility by integrating theoretical calculations, targeted design, high-throughput screening development sustainable solvents. Natural deep eutectic solvents (NADESs) optimized formulation were systematically designed selectively filtered from 1768 species, exhibiting...
Cardiovascular diseases are a major cause of mortality and disability worldwide. The present study investigated the cardio-protective effects polysaccharides extracted from Lycium barbarum (LB), fruit which is traditionally used in Chinese medicine. Polysaccharides were characterized using Fourier transform infrared spectroscopy high‑performance liquid chromatography techniques. demonstrated that LB composed glucose fructose monosaccharides molar ratio 1:2. A total 36 rats divided into three...
BACKGROUND:We performed non-targeted metabolomics analysis using liquid chromatography-mass spectrometry coupled technique to explore the biological mechanism of coronary artery disease (CAD) events for improved prediction. MATERIAL AND METHODS:We studied association CAD in 4092 individuals and observed replication sphingomyelin (28:1), lysophosphatidylcholine (18:2), (18:1), monoglyceride which were independent main risk factors. RESULTS:We found that these 4 metabolites responsible...
Based on the elastic analysis, existing methods of importance assessment structural members can only reflect behavior. To understand plasticity and stiffness degradation structure, present study proposes a member method which takes elastic-plastic strain energy or generalized as performance parameter. First, are explained. Second, by pushover is calculated in accordance with story force-displacement curve, according to base shear-top displacement curve. Third, measured its effect structure....
MicroRNAs (miRNAs) play important roles in the regulation of cell proliferation, differentiation, apoptosis, and inflammatory responses. MiR-142-5p is an inflammation-associated miRNA, whose abnormal expression has been associated with a variety inflammation-related diseases. However, role signaling pathways targeted by miR-142-5p acquired middle ear cholesteatoma (AMEC) have not fully elucidated. Cyclin-dependent kinase 5 (CDK5), special member CDK family compared classic cyclins that plays...
We study two unrelated machine scheduling problems with dependent release dates to minimize the makespan.For case fixed processing time where job $j$ on $i$ requires $p_{ij}$ and incurs a cost of $c_{ij}$,we derive $2$-approximation algorithm. For problem variable times increases linearly as decreases, we propose $(2+\epsilon)$-approximation