Wen‐Jun Tu

ORCID: 0000-0002-1703-1802
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Stroke Rehabilitation and Recovery
  • Metabolism and Genetic Disorders
  • Neurological Disease Mechanisms and Treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Corporate Finance and Governance
  • Mitochondrial Function and Pathology
  • International Business and FDI
  • Folate and B Vitamins Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Neonatal Health and Biochemistry
  • Venous Thromboembolism Diagnosis and Management
  • COVID-19 Clinical Research Studies
  • Intracranial Aneurysms: Treatment and Complications
  • Peroxisome Proliferator-Activated Receptors
  • Neurological Disorders and Treatments
  • Long-Term Effects of COVID-19
  • Autism Spectrum Disorder Research
  • Liver Disease Diagnosis and Treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Vitamin D Research Studies
  • Healthcare Systems and Reforms
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Atherosclerosis and Cardiovascular Diseases

Beijing Tian Tan Hospital
2018-2025

Capital Medical University
2016-2025

Chinese Institute for Brain Research
2021-2025

China National Nuclear Corporation
2025

Chengdu Medical College
2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2024

Peking Union Medical College Hospital
2017-2024

Ningbo University
2020-2024

Shanghai Jinyuan Senior High School
2024

University of California, San Diego
2024

Abstract Background In December 2019, a series of pneumonia cases unknown cause emerged in Wuhan, Hubei, China. this study, we investigate the clinical and laboratory features short-term outcomes patients with coronavirus disease 2019 (COVID-19). Methods All COVID-19 admitted to Wuhan University Zhongnan Hospital China, between 3 January 1 February 2020 were included. those laboratory-confirmed infections. Epidemiological, clinical, radiological characteristics; underlying diseases; tests;...

10.1093/cid/ciaa243 article EN cc-by Clinical Infectious Diseases 2020-03-13

<h3>Importance</h3> Stroke is the leading cause of death in China. However, recent data about up-to-date stroke burden China are limited. <h3>Objective</h3> To investigate urban-rural disparity Chinese adult population, including prevalence, incidence, and mortality rate, disparities between urban rural populations. <h3>Design, Setting, Participants</h3> This cross-sectional study was based on a nationally representative survey that included 676 394 participants aged 40 years older. It...

10.1001/jamanetworkopen.2023.1455 article EN cc-by-nc-nd JAMA Network Open 2023-03-02

In China, stroke is a major cause of mortality, and long-term physical cognitive impairment. To meet this challenge, the Ministry Health China Stroke Prevention Project Committee (CSPPC) was established in April 2011. This committee actively promotes prevention control China. With government financial support 838.4 million CNY, 8.352 people from 536 screening points 31 provinces have received follow-up over last seven years (2012–2018). 2016, CSPPC issued plan to establish centers. shorten...

10.1177/1747493020913557 article EN International Journal of Stroke 2020-03-29

BackgroundThe stroke burden in China has increased during the past 40 years. The present study aimed to determine recent trends prevalence of from 2013 2019 stratified by sociodemographic characteristics, including sex, age, residence, ethnicity, and province within a population-based screening project China.MethodsWe made use data generated Stroke High-risk Population Screening Program. All living subjects with confirmed at interview were considered have prevalent stroke. analyses weighted...

10.1016/j.lanwpc.2022.100550 article EN cc-by-nc-nd The Lancet Regional Health - Western Pacific 2022-07-30

Inflammation and activation of the neuroendocrine systems comprise important aspects stroke pathophysiology. The present study investigated whether baseline plasma brain natriuretic peptide (BNP), N-terminal pro-brain (NT-proBNP), cortisol copeptin levels on admission can predict short-term outcomes mortality after acute ischaemic stroke. group consisted 189 patients who had their first Plasma BNP, NT-proBNP, were evaluated to determine value with respect predicting functional outcome within...

10.1111/jne.12052 article EN Journal of Neuroendocrinology 2013-05-23

Low vitamin D levels have been reported to contribute the risk of cardiovascular events and mortality, especially stroke. In present study we therefore evaluated short-term prognostic value serum 25(OH)D (25-hydroxyvitamin D) in Chinese patients with AIS (acute ischaemic stroke). From February 2010 September 2012, consecutive stroke admitted emergency department at two hospitals Beijing, China were identified. Clinical information was collected, concentration NIHSS (National Institutes...

10.1042/cs20130284 article EN Clinical Science 2013-09-12

Bacillus subtilis is one of the most popular commercial probiotics used in farm animal production. However, its potential mechanisms are not very clear. The aim this study was to investigate effects dietary on intestinal histomorphology, innate immunity, microbiota composition, transcriptomics, and related metabolomics. Twenty-four 48-week-old Lohman Pink-shell laying hens were randomly divided into two groups: a basic diet supplemented with (0.5 g/kg) for 9-week experiment. At end...

10.1016/j.animal.2022.100474 article EN cc-by-nc-nd animal 2022-02-24

The history of the Newborn Screening Program in Mainland China begins 1981, when a pilot plan was developed that demonstrated feasibility its implementation. It has so far focused on detection congenital hypothyroidism (CH) and phenylketonuria (PKU) to prevent or reduce mental physical developmental retardation children. Throughout this period, total 35,795,550 dried blood samples (DBS) newborns (NB) have been analyzed for PKU, 35,715,988 CH. During 3,082 cases with PKU diagnosed, resulting...

10.1007/8904_2011_119 article EN JIMD Reports 2012-01-01

Background and Purpose— FABP4 (fatty acid–binding protein 4) is an intracellular lipid chaperone involved in coordination of transportation atherogenesis. This study aimed at observing the effect on 3-month outcomes Chinese patients with acute ischemic stroke. Methods— In a prospective multicenter observational study, serum concentrations were admission measured plasma 737 consecutive Serum FABP4, National Institutes Health Stroke Scale score, conventional risk factors evaluated to determine...

10.1161/strokeaha.117.017128 article EN Stroke 2017-05-10

Depression is a frequent mood disorder in stroke patient. Our aim was to determine irisin levels serum and investigate their associations with post-stroke depression (PSD) 6-month follow-up study Chinese patients first-ever acute ischemic (AIS). The subjects were AIS who hospitalized at three centers during the period from January 2015 December 2016. Neurological neuropsychological evaluations conducted follow-up. Serum concentrations measured by enzyme-linked immunosorbent assay (ELISA)....

10.1186/s12974-018-1177-6 article EN cc-by Journal of Neuroinflammation 2018-05-02

10.1016/j.techfore.2023.123136 article EN Technological Forecasting and Social Change 2023-12-26

Autism is a neurodevelopmental disability that usually diagnosed before age 3 years.(1) The need to understand the causes of autism and underlying pathophysiology has become more acute since number cases risen markedly.(2) Several recent research studies lend support hypothesis abnormalities involving plasma Amino Acids profiles have been implicated in etiology autism.(3,4) We designed preliminary prospective cohort study test amino acids profiles blood samples from patients with normal...

10.3164/jcbn.12-45 article EN Journal of Clinical Biochemistry and Nutrition 2012-01-01
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