A5100689732- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- MRI in cancer diagnosis
- Radiation Therapy and Dosimetry
- Moyamoya disease diagnosis and treatment
- Neurological Disease Mechanisms and Treatments
- Advanced MRI Techniques and Applications
- Nuclear Physics and Applications
- Peripheral Artery Disease Management
- Trauma and Emergency Care Studies
- Neuroscience of respiration and sleep
- Cardiac Valve Diseases and Treatments
- Neonatal Health and Biochemistry
- Medical Imaging and Analysis
- Retinal and Optic Conditions
- Neurological Complications and Syndromes
- Aortic aneurysm repair treatments
- Vascular Anomalies and Treatments
- Aortic Thrombus and Embolism
- Aortic Disease and Treatment Approaches
- Catalytic C–H Functionalization Methods
Henan Provincial People's Hospital
2012-2024
Zhengzhou University
2013-2024
National Clinical Research Center for Digestive Diseases
2024
Beijing Tian Tan Hospital
2024
Capital Medical University
2024
Weatherford College
2024
Henan University
2021-2023
China Institute of Atomic Energy
2023
State Key Laboratory of Pollution Control and Resource Reuse
2022
Nanjing University
2022
In acute ischemic stroke, there is uncertainty regarding the benefit and risk of administering intravenous alteplase before endovascular thrombectomy.We conducted a trial at 41 academic tertiary care centers in China to evaluate thrombectomy with or without patients stroke. Patients stroke from large-vessel occlusion anterior circulation were randomly assigned 1:1 ratio undergo alone (thrombectomy-alone group) preceded by alteplase, dose 0.9 mg per kilogram body weight, administered within...
In China, stroke is a major cause of mortality, and long-term physical cognitive impairment. To meet this challenge, the Ministry Health China Stroke Prevention Project Committee (CSPPC) was established in April 2011. This committee actively promotes prevention control China. With government financial support 838.4 million CNY, 8.352 people from 536 screening points 31 provinces have received follow-up over last seven years (2012–2018). 2016, CSPPC issued plan to establish centers. shorten...
Importance Endovascular therapy (EVT) demonstrated better outcomes compared with medical management in recent randomized clinical trials (RCTs) of patients large infarct. Objective To compare EVT vs across different strata the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and infarct core volume Design, Setting, Participants This prespecified secondary analysis subgroups Therapy Acute Anterior Circulation Large Vessel Occlusive Patients With a Infarct Core (ANGEL-ASPECT)...
Futile recanalization-when patients have a successful recanalization but fail to achieve satisfactory functional outcome- is common phenomenon of endovascular treatment acute ischemic stroke (AIS). The present study aimed identify the predictors futile in AIS who received treatment.This post-hoc analysis DIRECT-MT trial. Demographics, clinical characteristics, workflow interval times, biochemical parameters, and imaging characteristics were compared between meaningful groups. Multivariate...
Background Delayed ischemic stroke (DIS) is a rare complication that may occur in patients with cerebral aneurysms treated the Pipeline Embolization device (PED). This study aims to evaluate characteristics of DIS following PED placement and investigate optimal duration dual antiplatelet therapy (DAPT) relation incidence DIS. Methods We conducted multicenter retrospective cohort on consecutive cases intracranial PED. Patients were divided into two groups based timing DAPT switching...
BackgroundEndovascular therapy (EVT) was demonstrated effective in acute large vessel occlusion (LVO) with infarction. Revealing subgroups of patients who would or not benefit from EVT will further inform patient selection for EVT.MethodsThis post-hoc analysis the ANGEL-ASPECT trial, a randomised controlled trial 456 adult anterior-circulation LVO and infarction, defined by ASPECTS 3–5 infarct core volume 70–100 mL, enrolled 46 centres across China, between October 2, 2020 May 18, 2022....
Background The influence of leukoaraiosis in patients with acute ischemic stroke (AIS) given intra-arterial treatment (IAT) or without preceding intravenous thrombolysis (IVT) remains unknown. Objective To assess the clinical and radiological outcomes IAT leukoaraiosis. Methods Patients direct mechanical thrombectomy trial (DIRECT-MT) whose grade could be assessed were included. DIRECT-MT was a randomized performed China to effect compared plus IAT. We employed Age-Related White Matter...
Background: To investigate the effect of A Direct Aspiration First-Pass Thrombectomy (ADAPT) vs. Solumbra technique in treatment acute intracranial atherosclerosis-related large vessel occlusion (LVO). Methods: Patients with LVO who had undergone endovascular were retrospectively enrolled into two groups: The and ADAPT groups. clinical data analyzed. Results: (104) 48 56 group. mean time from femoral access to recanalization was significantly ( P < 0.05) shorter than at first line...
BACKGROUND: The efficacy of endovascular recanalization for internal carotid artery (ICA) terminus occlusion has not been completely evaluated. OBJECTIVE: To investigate the ICA occlusion. METHODS: Data from Direct-MT, a randomized controlled trial, were applied. occlusions diagnosed with preprocedure computed tomography angiography by core laboratory. We dichotomized into 2 groups (non-T and T) analyzed differences between them. Single-factor analysis multiple logistic regression applied to...
Background and purpose Clinical outcome in patients who received thrombectomy treatment is time-dependent. The of this study was to evaluate the efficacy one-stop stroke management (OSSM) platform reducing in-hospital workflow times receiving compared with traditional model. Methods data through OSSM protocol transshipment pathway were retrospectively analyzed compared. treatment-related time interval clinical two groups also assessed primary endpoint from door groin puncture (DPT). Results...
Objective To evaluate the recanalization efficacy and safety of a novel stent retriever in swine model acute arterial occlusion. Methods The JRecan thrombectomy device, with weaving design, was evaluated 18 occluded cervicocerebral vessels swine. flow restoration effect immediately upon deployment, reperfusion rate after retrieval, thromboembolic events, complications were assessed. histologic structure renal arteries passage measured to further assess JRecan. Results Immediate achieved...
Background Mechanical thrombectomy is the standard treatment for acute ischemic stroke (AIS) with large vessel occlusion (LVO) in anterior circulation. This trial aimed to indicate whether Skyflow, a new device, could achieve same safety and efficacy as Solitaire FR of AIS. Methods study was prospective, multicenter, randomized, single blind, parallel, positive controlled, non-inferiority clinical trial. Patients intracranial circulation LVO within 8 hours from onset were included receive...
The benefit of intravenous alteplase before endovascular thrombectomy is unclear in patients with acute cardioembolic stroke.We collected (CE) stroke patient data from the multicentre randomized clinical trial Direct Intra-arterial Thrombectomy to Revascularize Acute Ischaemic Stroke Patients Large Vessel Occlusion Efficiently Chinese Tertiary Hospitals (DIRECT-MT). primary outcome was 90-day modified Rankin Scale (mRS) score. Five subgroups were analyzed. A multivariable ordinal logistic...
Objective: In-stent restenosis (ISR) after stenting for intracranial stenosis is a significant issue. This study aimed to evaluate the usefulness of 3D T1-SPACE technique in follow-up patients stent implantation. Methods: Fifteen with arterial were prospectively enrolled 6–8 months stenting. Digital subtraction angiography (DSA) and imaging performed degree enhancement vessel wall. Bland–Altman plots used assess agreement between two methods, Pearson correlation coefficient was calculated as...
Purpose: The Tonbridge stent is a novel retriever with several design improvements which aim to achieve promising flow reperfusion in the treatment of acute ischemic stroke (AIS). We conducted randomized controlled, multicenter, non-inferiority trial compare safety and efficacy Solitaire FR. Methods: AIS patients aged 18–85 years large vessel occlusion anterior circulation who could undergo puncture within 6 h symptom onset were included. Randomization was performed on 1:1 ratio thrombectomy...
Huan Liu, Tianxiao Li, Yonghong Ding, Liangfu Zhu, Ferdinand K. Hui, Tengfei Zhou, Juha Antero Hernesniemi, Yanyan He, Yingkun He
There is no consensus on the optimal treatment for non-acute symptomatic intracranial vertebral artery occlusion, and endovascular recanalization a challenging procedure. We report our clinical experience of in patients with occlusion to assess feasibility safety determine candidate this Ninety-two who underwent from January 2019 December 2021 were retrospectively analyzed. we grouped all according imaging examination findings, length, duration, nature, calcification, angulation evaluate...
Abstract Objective. A scintillator is a luminescent material that converts high-energy photons into visible light and widely used in medical imaging. Different scintillators are applied to gamma imaging proton therapy boron neutron capture (BNCT). pixelated suitable for position measurement. The energy resolution, detection efficiency measurement of coupled SiPM were investigated via two kinds detectors. goal this manuscript was accurately measure the source through spectrum analysis...