A5061580592- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Cardiovascular and Diving-Related Complications
- Cardiovascular Health and Disease Prevention
- Neuroscience and Neuropharmacology Research
- Neurosurgical Procedures and Complications
- Optical Imaging and Spectroscopy Techniques
- Cardiac Ischemia and Reperfusion
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Heart Rate Variability and Autonomic Control
- Blood Pressure and Hypertension Studies
- Alzheimer's disease research and treatments
- Neurogenesis and neuroplasticity mechanisms
- Cerebral Venous Sinus Thrombosis
- S100 Proteins and Annexins
First Bethune Hospital of Jilin University
2012-2025
Yangzhou University
2022-2025
Jilin University
2015-2024
First Hospital of Jilin University
2015-2024
Binzhou University
2017-2024
Binzhou Medical University
2017-2024
Army Medical University
2022-2024
Daping Hospital
2024
First Affiliated Hospital of Xinjiang Medical University
2024
Xinjiang Medical University
2024
<h3>Importance</h3> Stroke is the leading cause of death in China. However, recent data about up-to-date stroke burden China are limited. <h3>Objective</h3> To investigate urban-rural disparity Chinese adult population, including prevalence, incidence, and mortality rate, disparities between urban rural populations. <h3>Design, Setting, Participants</h3> This cross-sectional study was based on a nationally representative survey that included 676 394 participants aged 40 years older. It...
In China, stroke is a major cause of mortality, and long-term physical cognitive impairment. To meet this challenge, the Ministry Health China Stroke Prevention Project Committee (CSPPC) was established in April 2011. This committee actively promotes prevention control China. With government financial support 838.4 million CNY, 8.352 people from 536 screening points 31 provinces have received follow-up over last seven years (2012–2018). 2016, CSPPC issued plan to establish centers. shorten...
BackgroundThe stroke burden in China has increased during the past 40 years. The present study aimed to determine recent trends prevalence of from 2013 2019 stratified by sociodemographic characteristics, including sex, age, residence, ethnicity, and province within a population-based screening project China.MethodsWe made use data generated Stroke High-risk Population Screening Program. All living subjects with confirmed at interview were considered have prevalent stroke. analyses weighted...
Abstract The atomically monodispersed dual‐atom nanozyme not only possesses the advantages of homogeneous active centers and high atomic utilization efficiency but also exhibits amazing synergistic effect for higher catalytic activities than single‐atom nanozyme. However, how to construct with multi‐enzyme cascade capacity protecting against brain tissue damage is a great challenge. Herein, coping secondary caused by explosive generation reactive oxygen species(ROS) during cerebral...
The protective effects of remote ischemic conditioning (RIC) on acute stroke have been reported. However, the mechanisms RIC not fully elucidated. This study aimed to investigate whether could reduce oxidative stress and inflammatory responses in middle cerebral artery occlusion (MCAO)-reperfusion mice via nuclear factor-E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway. C57BL/6 were subjected MCAO underwent twice daily at 1, 3, 7 days after MCAO. ML385 was used specifically inhibit...
To date, the benefit of intravenous thrombolysis for acute ischemic stroke (AIS) patients without advanced neuroimaging selection is confined to within 4.5 h onset. Our phase II EXIT-BT (Extending tIme window Thrombolysis by ButylphThalide up 6 after onset) trial suggested safety, feasibility, and potential tenecteplase (TNK) in AIS between The EXIT-BT2 a pivotal study undertaken confirm or refute this signal.
Backgrounds. The prevalence of diabetes has increased with the increase obesity, and finding indicators to predict risk become an urgent need. purpose this study is compare correlation between four anthropometric indices diabetes. Methods. A total 4052 participants aged 40 years above were selected in Dehui City, Jilin Province, using a multistage stratified whole group sampling method. Face-to-face interviews physical examinations conducted. Multivariate logistic analysis was used. values...
Cerebral autoregulation is crucial in patients with intracerebral hemorrhage. Dynamic cerebral probably altered acute hemorrhage; however, the temporal course of dynamic and its correlation clinical factors outcomes are poorly understood.Forty-three supratentorial hemorrhage (53.7±10.0 years old, 30 men) were enrolled for serial measurements performed on days 1 to 2, 4 6, 10 12, after ictus. Noninvasive continuous blood flow velocity arterial pressure recorded simultaneously using...
Cerebral ischemia/reperfusion injury (CIRI) is a major contributor to poor prognosis of ischemic stroke. Flavonoids are broad family plant polyphenols which abundant in traditional Chinese medicine (TCM) and have beneficial effects on several diseases including Accumulating studies indicated that flavonoids derived from herbal TCM effective alleviating CIRI after stroke vitro or vivo , exhibit favourable therapeutical potential. Herein, we systematically review the classification, metabolic...
The advancement of exosome studies has positioned engineered exosomes as crucial biomaterials for the development advanced drug delivery systems. This study focuses on developing a hybrid system by fusing mesenchymal stem cells (MSCs) with folate-targeted liposomes. aim was to improve loading capacity and target modification nanocarriers delivering first-line chemotherapy paclitaxel (PTX) its effectiveness assessed through cellular uptake evaluate ability deliver drugs tumor in vitro....
Alzheimer's disease (AD) is a progressive neurodegenerative associated with senile beta-amyloid (Abeta) plaques and cognitive decline. Neurogenesis in the adult hippocampus implicated regulating learning memory, increased human postmortem brain of AD patients. However, little currently known about changes hippocampal neurogenesis progression AD. As tissues from patients during are generally not available, an amyloid precursor protein (APP)/presenilin1 (PS1) double transgenic mouse model was...
Dyslipidemia is an important independent modifiable risk factor for cardiovascular disease. The aim of this study was to explore the current prevalence, awareness, treatment and control dyslipidemia its associated influence factors in northeast China.In population-based cross-sectional study, we adopted a multi-stage, stratified sampling method obtain representative sample 4052 permanent residents aged 40 years over from different urban rural regions Dehui City Jilin Province. All subjects...
Objectives Epidemiological studies aimed at stroke and its risk factors can help identify persons higher therefore promote prevention strategies. We to explore the current prevalence of associated in northeast China. Design Population based cross sectional study. Setting Data were collected using a structured precoded questionnaire designed by Stroke Screening Prevention Programme National Health Family Planning Commission China, between January March 2016. Participants 4100 permanent...