A5076462534- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular and Diving-Related Complications
- Cardiovascular Health and Disease Prevention
- Cerebral Venous Sinus Thrombosis
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Radiation Dose and Imaging
- Neurological Disorders and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Neurological disorders and treatments
- Optical Imaging and Spectroscopy Techniques
- Cardiac Imaging and Diagnostics
- Obstructive Sleep Apnea Research
- Peripheral Neuropathies and Disorders
- S100 Proteins and Annexins
- Cerebrospinal fluid and hydrocephalus
- Congenital Heart Disease Studies
- Migraine and Headache Studies
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and genetic disorders
- Parkinson's Disease Mechanisms and Treatments
- Heart Rate Variability and Autonomic Control
Capital Medical University
2021-2024
Chinese Institute for Brain Research
2021-2024
Jilin University
2014-2023
First Hospital of Jilin University
2014-2023
Capital University
2022-2023
Xuan Wu Hospital of the Capital Medical University
2022-2023
Peking University
2023
First Bethune Hospital of Jilin University
2012-2018
Changchun University of Chinese Medicine
2017
Shenzhen University
2016
<h3>Importance</h3> The crtierion standard method for monitoring intracranial pressure (ICP) can result in complications and pain. Hence, noninvasive, repeatable methods would be valuable. <h3>Objective</h3> To examine how ultrasonographic optic nerve sheath diameter (ONSD) correlated with noninvasive dynamically monitored ICP changes. <h3>Design, Setting, Participants</h3> ONSD was measured before the lumbar puncture (LP) 60 patients on admission. Patients elevated were divided into group 1...
Cerebral autoregulation is crucial in patients with intracerebral hemorrhage. Dynamic cerebral probably altered acute hemorrhage; however, the temporal course of dynamic and its correlation clinical factors outcomes are poorly understood.Forty-three supratentorial hemorrhage (53.7±10.0 years old, 30 men) were enrolled for serial measurements performed on days 1 to 2, 4 6, 10 12, after ictus. Noninvasive continuous blood flow velocity arterial pressure recorded simultaneously using...
Abstract: PURPOSE: In patients undergoing endovascular thrombectomy (EVT) with acute ischemic stroke (AIS), dynamic cerebral autoregulation (dCA) may minimize neurological injury from blood pressure fluctuations. This study set out to investigate the function of dCA in predicting clinical outcomes following EVT. METHODS: 43 AIS middle or internal carotid artery underwent EVT, and healthy individuals (controls) were enrolled this case control research. The was evaluated using transcranial...
Ultrasonography of the optic nerve sheath diameter (ONSD) is a non-invasive and rapid method that might be helpful in identification increased intracranial pressure (ICP). The use an ONSD greater than 5 mm on ultrasound as indicator ICP Caucasian population has been studied. However, cut-off point this predictor Chinese patients not established. Thus, we conducted study to identify criterion for detection elevated opening lumbar puncture (LP) investigate influencing factors. This was blind...
Dyslipidemia is an important independent modifiable risk factor for cardiovascular disease. The aim of this study was to explore the current prevalence, awareness, treatment and control dyslipidemia its associated influence factors in northeast China.In population-based cross-sectional study, we adopted a multi-stage, stratified sampling method obtain representative sample 4052 permanent residents aged 40 years over from different urban rural regions Dehui City Jilin Province. All subjects...
Objectives Epidemiological studies aimed at stroke and its risk factors can help identify persons higher therefore promote prevention strategies. We to explore the current prevalence of associated in northeast China. Design Population based cross sectional study. Setting Data were collected using a structured precoded questionnaire designed by Stroke Screening Prevention Programme National Health Family Planning Commission China, between January March 2016. Participants 4100 permanent...
To investigate the existence of an association between compensatory remodeling in symptomatic middle cerebral artery atherosclerotic stenosis with high-resolution magnetic resonance imaging (HR MRI) and transcranial color Doppler monitoring microembolic signals (MESs).A total 36 consecutive patients underwent MES by 3-T HR MRI. Proton density-weighted cross-sectional images submillimeter voxel size were obtained. The patterns plaque morphology sites maximal luminal narrowing analyzed terms...
Stroke of large-artery atherosclerosis and small-artery occlusion are two main subtypes stroke according to TOAST classification. The underlying mechanisms how these affect dynamic cerebral autoregulation (dCA) might be heterogeneous, resulting in varied clinical conditions outcomes. We therefore studied the pattern dCA subtypes.Forty-one patients with acute unilateral middle artery (MCA) territory (15 ipsilateral 26 occlusion) 20 healthy volunteers were enrolled. Non-invasive continuous...
Abstract We aimed to quantitatively assess intracranial pressure (ICP) using optic nerve sheath diameter (ONSD) measurements. recruited 316 neurology patients in whom ultrasonographic ONSD was measured before lumbar puncture. They were randomly divided into a modeling and test group at ratio of 7:3. In the group, we conducted univariate multivariate analyses associations between ICP ONSD, age, sex, BMI, mean arterial blood pressure, diastolic pressure. derived mathematical function “Xing...
Abstract Cerebral small vessel disease is a major cause of stroke and vascular dementia; however, the pathogenesis largely unclear. In this study, we investigated characteristics impairment dynamic cerebral autoregulation (dCA) in lacunar infarction patients. Seventy-one patients were enrolled including 46 unilateral middle artery (MCA) territory 25 posterior (PCA) Each group was randomly divided into two subgroups. Group 1 underwent dCA assessments bilateral MCAs 2 PCAs. All followed up for...
Abstract Introduction: The purpose of this study was to assess the electrophysiological subtypes and prognosis Guillain–Barré syndrome (GBS) in northeastern China. Methods: Ninety‐nine patients with GBS were recruited between 2006 2010 retrospectively reviewed. Results: Sixty‐seven percent had acute inflammatory demyelinating polyneuropathy (AIDP). Patients motor axonal neuropathy (AMAN) more severe symptoms at onset GBS, intravenous immunoglobulin (IVIg) less effective these patients. may...
Carotid plaque echolucency as detected by Color Doppler ultrasonography (CDUS) has been used a potential marker of vulnerability. However, contrast-enhanced ultrasound (CEUS) recently shown to be valuable method evaluate the vulnerability and neovascularization within carotid atherosclerotic plaques. The aim this study was compare CEUS CDUS in assessment using transcranial color (TCD) monitoring microembolic signals (MES) reference technique.A total 46 subjects with arterial stenosis (≥ 50%)...
The aim of this multicenter study was to demonstrate the distribution pattern atherosclerotic stenosis and its trend with aging between extracranial intracranial arteries anterior posterior circulations in Chinese patients hospitalized ischemic stroke. In addition, risk factors for were illustrated. From June 2015 May 2016, 9,346 stroke from 20 hospitals enrolled. Carotid artery ultrasonography transcranial color-coded sonography/transcranial Doppler used evaluate arteries. analyzed....
Background and Purpose The relationship between right-to-left shunts (RLS) migraine cryptogenic stroke is not well understood. In this study, we investigated whether RLS are associated with impairment of dynamic cerebral autoregulation (dCA), which may play a role in stroke. Methods Sixty-six migraineurs were enrolled the including 36 non-RLS patients 30 patients. Non-invasive continuous blood flow velocity arterial pressure recorded simultaneously from each patient by using transcranial...
Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcranial Doppler (TCD) increasingly used as an indirect measure of ICP, quantitative EEG (QEEG) can reflect the coupling CBF We aimed combine TCD QEEG comprehensively assess function ICH provide prognostic diagnosis.We prospectively enrolled patients with severe acute supratentorial (SAS)-ICH...
Background The association between RLS and migraine is still debated. aim of this study to investigate the prevalence grade in Chinese patients with evaluate relationship migraine. Methods A multi-center case-control contrast-enhanced transcranial Doppler was conducted 931 consecutive (240 had aura 691 were without group) 282 healthy adults. Clinical trial no. NCT02425696. Results 63.8% 39.9% group (MA+) (MA−), respectively, significantly higher than that (29.4%, p < 0.001; 0.001)....
Intraplaque neovascularisation (IPN) increases the vulnerability of plaques, which makes them more likely to rupture and risk vascular events. However, it is unclear whether IPN can predict future events (stroke recurrence cardiovascular events). Previous studies on have focused patients with severe stenosis but overlooked mild moderate stenosis. This study aimed investigate assessed by contrast-enhanced ultrasonography (CEUS) in degrees associated events.One hundred twenty-one participated...