A5101608587- Migraine and Headache Studies
- Cerebral Venous Sinus Thrombosis
- Acute Ischemic Stroke Management
- Peripheral Neuropathies and Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Syncope and Autonomic Disorders
- Cerebrovascular and Carotid Artery Diseases
- Hereditary Neurological Disorders
- Neurosurgical Procedures and Complications
- Sympathectomy and Hyperhidrosis Treatments
- Systemic Lupus Erythematosus Research
- Otolaryngology and Infectious Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Trigeminal Neuralgia and Treatments
- Neurological Complications and Syndromes
- Ophthalmology and Eye Disorders
- Long-Term Effects of COVID-19
- Lysosomal Storage Disorders Research
- Facial Nerve Paralysis Treatment and Research
- Medicinal plant effects and applications
- Neonatal and Maternal Infections
- Psychosomatic Disorders and Their Treatments
- Cerebrovascular and genetic disorders
- Kruppel-like factors research
- Moyamoya disease diagnosis and treatment
Jilin University
2012-2023
First Hospital of Jilin University
2012-2023
First Bethune Hospital of Jilin University
2012-2019
Second Affiliated Hospital of Jilin University
2017
Ultrasonography of the optic nerve sheath diameter (ONSD) is a non-invasive and rapid method that might be helpful in identification increased intracranial pressure (ICP). The use an ONSD greater than 5 mm on ultrasound as indicator ICP Caucasian population has been studied. However, cut-off point this predictor Chinese patients not established. Thus, we conducted study to identify criterion for detection elevated opening lumbar puncture (LP) investigate influencing factors. This was blind...
The objective of this study was to test the validity, in Chinese population, Lifting Burden diagnostic questionnaire for purpose a population-based survey burden headache China. From all regions China, sample 417 respondents had completed structured door-to-door conducted by neurologists from local hospitals calling unannounced. They were contacted re-interview telephone specialists who unaware diagnoses. A screening question ascertained whether occurred last year. If they had, applied their...
Abstract We aimed to quantitatively assess intracranial pressure (ICP) using optic nerve sheath diameter (ONSD) measurements. recruited 316 neurology patients in whom ultrasonographic ONSD was measured before lumbar puncture. They were randomly divided into a modeling and test group at ratio of 7:3. In the group, we conducted univariate multivariate analyses associations between ICP ONSD, age, sex, BMI, mean arterial blood pressure, diastolic pressure. derived mathematical function “Xing...
The objective of this study is to evaluate the association between body mass index (BMI) and migraine in general population Chinese cohort. This was a cross-sectional secondary analysis from cohort men women reproductive post-reproductive age ranging 18 65 years. Migraine defined utilizing ICHD criteria. Body indices were calculated using measured height weight categorized based on World Health Organizations 1-year period prevalence 9.3 %. No identified those with BMI < 30.0. Compared normal...
Abstract Background In order to know the status quo of health care for primary headache disorders in China, questions about consultation and diagnosis were included a nationwide population-based survey initiated by Lifting The Burden : Global Campaign against Headache. Methods Throughout 5,041 unrelated respondents aged 18–65 years randomly sampled from general population visited unannounced at their homes. After basic sociodemographic diagnostic questions, with answered further health-care...
Background In order to minimize recall bias in burden estimation, questions about headache yesterday were included a population-based survey initiated by Lifting The Burden: Global Campaign against Headache. Methods Throughout China, nonrelated respondents aged 18–65 years randomly sampled from the general population door-to-door survey. A validated structured questionnaire inquiry into occurrence and of on preceding day (“headache yesterday”). Results participation rate was 94.1%. Of 5041...
Background: Dystonia is defined as the presence of sustained involuntary muscle contractions, often leading to abnormal posture and movement. DYT1 caused by a mutation in TOR1A gene, whilst mutations THAP1 gene have been identified responsible for DYT6. The relative frequency phenotype differences between DYT6 amongst Chinese primary dystonia patients not well-characterized. Patients methods: One hundred eleven unrelated with were screened genes, correlate this clinical presentation. Exon 5...
Background Recently, contrast‐enhanced transcranial D oppler ( cTCD ) studies have shown that right‐to‐left shunt RLS may be a risk factor for migraine in W esterners; however, limited data the literature describes prevalence of Chinese patients with migraine. Objective To assess C hina and to evaluate relationship between extent Methods A total 217 consecutive diagnosis 100 volunteers were recruited. c TCD was used all subjects. Results In group, rate positive 44.2% (96/217), 23.5% (51/217)...
To explore the role of rs11053646 polymorphism oxidized low-density lipoprotein receptor 1 (OLR-1) gene in susceptibility and prognosis ischemic stoke (IS).A total 304 IS patients 377 age sex-matched healthy controls were recruited. Patients followed up for 6 months recovery evaluation stroke. Genotyping analyses G > C polymorphisms OLR1 performed.The genotype frequencies alleles at significantly differed between stroke subjects control (both P < 0.001). The presence CC was higher than (38%...
Abstract Facial nerve paralysis is a common complication following cerebellopontine angle (CPA) surgery. This study investigated the prognostic value of facial motor-evoked potentials (FNMEPs) elicited by transcranial electrical stimulation for outcome after CPA tumorectomy. A total 95 patients were enrolled in this between January 2014 and 2016. All these underwent tumorectomy (unilateral, n = 95; bilateral, 1). Intraoperative FNMEP was recorded. The short- long-term postoperative functions...
Myasthenia gravis (MG) is an autoimmune disorder mediated by antibodies against the acetylcholine receptors (AChR) of skeletal muscles. An imbalance in various T helper (Th) cells, including Th1, Th2, Th17, Th22 and follicular (TFH) has been found associated with immunological disturbances.In this study, we aim to investigate role Th cells peripheral blood MG patients.A total 33 patients 34 age matched controls were enrolled study. Peripheral mononuclear (PBMCs) isolated using Ficoll-Paque...
Rationale: Mixed connective tissue disease (MCTD) refers to an overlapping condition of different autoimmune disorders such as systemic lupus erythematosus, cutaneous sclerosis, rheumatoid arthritis, polymyositis, and dermatomyositis. However, MCTD manifesting transverse myelitis is extremely rare. Herein, we report a case with both central peripheral nervous system involvement. Patient concerns: We describe discuss the clinical findings management 36-year-old man presented 2-week history...
Objective . To investigate the efficacy and safety of traditional Chinese medicine Duliang soft capsule (DSC) in prophylactic treatment for patients with chronic daily headache (CDH). Methods A multicenter, double-blind, randomized, placebo-controlled clinical study was conducted at 18 centers. The participants received either DSC or placebo 4 weeks. primary measure headache-free rate (HFR) a 4-week period between pretreatment posttreatment stages. secondary measures were decrease days,...
Both hypertension (HTN) and headache disorders are highly prevalent worldwide. Our purpose, in a nationwide study of the Chinese general population, was to evaluate any association between primary elevated blood pressure (eBP). We could not collect data on antihypertensive therapy, but took view that, whatever such therapy might be taken, eBP sign that it failing meet treatment needs. Therefore, as secondary important from public-health perspective, we would present prevalence (treated or...
Rationale: The ischemic penumbra assessment is essential for the subsequent therapy and prediction of evolution in patients with acute infraction. Although controversial as a perfect equivalence to penumbra, perfusion-weighted imaging (PWI)-diffusion-weighted (DWI) mismatch may predict response thrombolysis. Due reliance PWI on contrast agents, noninvasive alternatives remain an unmet need. Patient concerns: We reported 65-year-old man complained paroxysmal hemiplegia his right limbs anepia...
The aim of this study was to determine the associations between serum folate level and clinical course severity Guillain-Barré syndrome (GBS). We retrospectively enrolled 112 pairs GBS patients age- sex-matched healthy controls with measured levels. On admission, 21 (18.9%) had deficiency, which only two were female patients. Patients normal levels a shorter disease progression than those deficiency (median duration: 6 versus 13 days, p < 0.001). Serum on admission correlated duration...
Posterior reversible encephalopathy syndrome (PRES) is a relatively rare clinical disease, characterized by subcortical vasogenic edema. Here, we present the first reported case of PRES induced anlotinib, multi-target tyrosine kinase inhibitor. A 56-year-old female patient with lung adenocarcinoma and bone metastasis experienced hypertension mental confusion when she received anti-angiogenesis treatment. was diagnosed after magnetic resonance patient's brain revealed hyperintensities...