A5101705897- Gastric Cancer Management and Outcomes
- Cancer Immunotherapy and Biomarkers
- Neuroendocrine Tumor Research Advances
- Metastasis and carcinoma case studies
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Cerebrovascular and Carotid Artery Diseases
- Gastrointestinal Tumor Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Moyamoya disease diagnosis and treatment
- Immune Cell Function and Interaction
- Immune cells in cancer
- Ginseng Biological Effects and Applications
- Lung Cancer Research Studies
- Acute Myocardial Infarction Research
- Renal cell carcinoma treatment
- Organ Transplantation Techniques and Outcomes
- Folate and B Vitamins Research
- Alzheimer's disease research and treatments
- Peripheral Neuropathies and Disorders
- Pancreatitis Pathology and Treatment
- Traumatic Brain Injury Research
Shanghai Jiao Tong University
2014-2024
Shanghai Sixth People's Hospital
2007-2024
Wuxi Ninth People's Hospital
2024
Soochow University
2024
Ruijin Hospital
2012-2024
State Key Laboratory of Polymer Physics and Chemistry
2024
Chinese Academy of Sciences
2024
Changchun Institute of Applied Chemistry
2024
Chongqing Medical University
2024
XinHua Hospital
2024
<h3>Importance</h3> Uncertainty remains about the efficacy of folic acid therapy for primary prevention stroke because limited and inconsistent data. <h3>Objective</h3> To test hypothesis that with enalapril is more effective in reducing first than alone among Chinese adults hypertension. <h3>Design, Setting, Participants</h3> The China Stroke Primary Prevention Trial, a randomized, double-blind clinical trial conducted from May 19, 2008, to August 24, 2013, 32 communities Jiangsu Anhui...
Advanced gastric cancer (AGC) has high morbidity and mortality in East Asia, it is urgent to explore new treatments improve patient prognosis. Programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors have exhibited remarkable activity clinical trials were approved by the FDA for therapy several types of tumors. Here, we evaluated PD-L1 expression T cell infiltration AGC. Positive tumor was detected 171 AGCs (33.60%) out 509 AGCs. positively correlated with CD8 + infiltration....
<h3>Importance</h3> Gastric neuroendocrine carcinoma and mixed adenoneuroendocrine are rare pathological types of gastric cancer, there is a lack multicenter studies comparing the prognosis recurrence patterns carcinoma, adenocarcinoma. <h3>Objective</h3> To compare differences in long-term survival among <h3>Design, Setting, Participants</h3> This cohort study included patients with resectable at 23 hospitals China from January 2006 to December 2016. In addition, adenocarcinoma were...
Abstract Wound healing and infection remain significant challenges due to the ineffectiveness against multidrug‐resistant (MDR) bacteria complex oxidative wound microenvironments. To address these issues, thymoquinone‐reinforced injectable thermosensitive TQ@PEG‐PAF‐Cur hydrogels with dual functions of microenvironment reshaping photodynamic therapy are developed. The hydrogel comprises natural compound thymoquinone (TQ) poly (ethylene glycol)‐block‐poly (alanine‐co‐phenyl alanine)...
Gastric cancer (GC) remains a refractory worldwide. Currently, exploring the differences of immune status in GC patients with different subgroups might provide promising immunotherapeutic approaches for treatment GC.In this study, total 598 surgically resected FFPE primary gastric samples were assessed FOXP3, CD163, CD3, CD8, and PD-L1 markers. The correlations between markers expression clinicopathological features prognosis investigated retrospectively.In general, PD-L1, CD8 could be...
Smoking remains a strong risk factor for premature death. This study examines the associations of nondaily smoking, daily and smoking cessation with risks mortality from all causes, cardiovascular disease, cancer.This used data National Health Nutrition Examination Survey, population-based, cross-sectional study. Data analysis was conducted in U.S. January to October 2020. Cox proportional hazard regression models were obtain adjusted ratios.During 255,100 person-years follow-up, 2,008...
We aimed to investigate the relationship of time-averaged on-treatment systolic blood pressure (SBP) with risk first stroke in CSPPT (China Stroke Primary Prevention Trial). A post hoc analysis was conducted using data from 17 720 hypertensive adults without cardiovascular disease, diabetes mellitus, and renal function decline CSPPT, a randomized double-blind controlled trial. The primary outcome stroke. Over median follow-up duration 4.5 years, association between averaged SBP for stoke...
Abstract A newly identified novel coronavirus (2019-nCoV) has caused numerous acute respiratory syndrome cases in Wuhan China from December 2019 to Feb 2020. Its fast spreading other provinces and overseas is very likely causing a pandemic. Since the been reported be capable of endangering thousands lives, it extremely important find out how transmitted human organs. Apart fever complications, gastrointestinal symptoms are observed some patients with 2019-nCoV but significance remains...
Acute kidney injury (AKI) is a common serious complication in sepsis patients with high mortality rate. This study aimed to develop and validate predictive model for associated acute (SA-AKI).
Abstract Introduction Accurate assessment of prognosis for patients with unresponsive wakefulness syndrome (UWS; formerly vegetative state) may help clinicians and families guide the type intensity therapy; however, there is no suitable accurate means to predict outcome so far. We aimed develop a simple bedside scoring system likelihood awareness recovery in UWS. Methods prospectively enrolled 56 (age range 10 73 years) UWS 3 12 weeks post-onset. collected demographic data performed...
The dynein axonemal heavy chain (DNAH) family of genes encode the chain, which is involved in cell motility. Genomic variations DNAH members have been frequently reported diverse kinds malignant tumors. In this study, we analyzed genomic database to evaluate mutation status gastric adenocarcinoma and further identified significance mutant as effective molecular biomarkers for predicting chemotherapy response cancer patients. We clinical data patients published Cancer Genome Atlas (TCGA)...
Abstract Hexagonal boron nitride (h‐BN) with low dielectric loss and high temperature resistance opens up new opportunities for the preparation of polymer‐derived SiCN ceramics (PDCs‐SiCN ceramics) excellent mechanical properties. BN‐containing composite (PDCs‐SiCN(BN) different BN content were prepared via a pyrolysis process ball‐milling‐blended Polyvinylsilazane/boron (PVSZ/BN) precursors. is stably embedded in tissue tightly bound it. The appropriate greatly improves properties PDCs‐SiCN...