A5101837056- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Neuroendocrine Tumor Research Advances
- Metastasis and carcinoma case studies
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Diet, Metabolism, and Disease
- Gastrointestinal motility and disorders
- Pancreatic and Hepatic Oncology Research
- Gut microbiota and health
- Liver Disease and Transplantation
- Probiotics and Fermented Foods
- Enhanced Recovery After Surgery
- Gestational Trophoblastic Disease Studies
- Internet Traffic Analysis and Secure E-voting
- Phagocytosis and Immune Regulation
- Pancreatic function and diabetes
- Dysphagia Assessment and Management
- Respiratory and Cough-Related Research
- Neurofibromatosis and Schwannoma Cases
Southern Medical University
2016-2025
Nanfang Hospital
2016-2025
Zhuhai People's Hospital
2024-2025
Jinan University
2024-2025
Fujian Normal University
2024
Southend Hospital
1995
Recurrent bleeding from the small intestine accounts for 5 to 10% of cases gastrointestinal and remains a therapeutic challenge. Thalidomide has been evaluated treatment recurrent due small-intestinal angiodysplasia (SIA), but confirmatory trials are lacking.
Abstract Background and Aim Fexuprazan is a novel potassium‐competitive acid blocker (P‐CAB). This study aimed to explore the noninferior efficacy safety of fexuprazan esomeprazole in treating erosive esophagitis (EE). Methods was phase III, randomized, double‐blind multicenter study. Patients with endoscopically confirmed EE were randomized receive 40 mg or once daily for 4–8 weeks. The healing rates EE, symptom response, GERD‐health‐related quality life (GERD‐HRQL), treatment‐emergent...
Inflammatory bowel disease (IBD) is characterized by disturbance of pro-inflammatory cytokines and anti-inflammatory cytokines. Previous studies have demonstrated the effect cytokines, such as interleukin-10 (IL-10) or IL-4 on IBD, but their data were controversial. This study further investigated (IL-4), IL-10 combination treatment trinitrobenzenesulfonic acid (TNBS)-induced murine colitis.pcDNA3.0 carrying cDNA was encapsulated with LipofectAMINE 2000 intraperitoneally injected into mice...
Abstract Background and Aim Laparoscopic resection (LAP) endoscopic submucosal dissection (ESD) of small gastrointestinal stromal tumors (GISTs) have been reported by large amount literature. However, the management GISTs remains controversial. This study evaluated efficacy ESD LAP for gastric provided long‐term outcomes two methods. Methods A total 126 patients who underwent or between 2009 2016 were retrospectively collected from medical records in our hospital, we made telephone follow‐up...
Although recent guidelines recommend endoscopic resection of rectal neuroendocrine tumors (NET) ≤10 mm, there is no consensus on which modality should be performed. We aimed to compare the safety and efficacy modified cap-assisted mucosal (mEMR-C) submucosal dissection (ESD) methods for treatment NET mm.A randomized noninferiority trial comparing mEMR-C ESD was conducted. The primary outcome histological complete rate; secondary outcomes included en bloc rate, operation time, complications,...
We propose a multi-feature fusion model based on manually extracted features and deep learning from endoscopic images for grading rebleeding risk of peptic ulcers. Based the appearance ulcers, color were to distinguish active bleeding (Forrest I) non-bleeding ulcers II III). The edge texture used describe morphology in different grades. By integrating network with visual features, representation was created predict In dataset consisting 3573 708 patients Forrest classification, proposed...
Previous studies on the association between non-skimmed milk consumption and non-alcoholic fatty liver disease (NAFLD) have reported inconsistent findings, with some suggesting an increased risk others indicating a protective effect. Moreover, as research focus has shifted globally from NAFLD to metabolic dysfunction-associated (MAFLD), there remains limited evidence relationship MAFLD. The objective of this cross-sectional study was investigate using data National Health Nutrition...
Irbesartan has shown significant therapeutic effects in hypertensive patients with non-alcoholic fatty liver disease (NAFLD). To determine the underlying mechanisms of its action, we established an vitro model NAFLD by treating human and mouse hepatocytes free acids (FFAs) angiotensin (Ang) II. significantly reversed AngII/FFA-induced lipid deposition mitochondrial dysfunction restoring ATP production membrane potential (MMP), decreasing levels reactive oxygen species (ROS) inflammatory...
Objectives: Surgery is still the main means for removing retained endoscopic capsules. This study intended to evaluate risk factors surgery in patients with capsule retention.Materials and methods: The data of 5348 consecutive endoscopy examinations were retrospectively analyzed. Cox regression analysis was used factors.Results: Seventy-seven (1.4%) had retention. Spontaneous passage occurred 16 patients, which 14 asymptomatic. Successful retrieval by double-balloon enteroscopy (DBE)...
Aims . The association between Helicobacter pylori ( H. ) infection and diarrhea-predominant irritable bowel syndrome (IBS-D) is still controversial. Here we performed a retrospective study to explore this issue. Methods A total of 502 inpatients with Rome III confirmed IBS-D known status from 8 hospitals were enrolled. pylori- positive patients, hospitalized in the recent year, followed up evaluate effects eradication on clinical course. Results Of 206 -positive, an rate that has no...
Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic diseases. In this prospective study, we aim to explore role angiotensin II (Ang II) and NLRP3 inflammasome in NAFLD patients. We prospectively enrolled 96 patients our hospital from September 2014 February 2016. Patients were divided into two groups (NAFLD group Control group), serum Ang level, IL-1β, IL-18, lipids analyzed. Correlation multivariable analyses used order identify potential risk factors NAFLD....
Peroral endoscopic myotomy (POEM) was initially developed for the treatment of achalasia. This study aimed to investigate feasibility and safety a stepwise approach POEM in management achalasia.A total five ex-vivo porcine esophagus-stomach training models were created performed. Then, 25 patients with achalasia treated similarly. The Eckardt score, barium esophagrams, high-resolution manometry used evaluate its efficacy.POEM procedures completed stomach-esophagus models, perforations...